Compile Data Set for Download or QSAR
maximum 50k data
Found 307 with Last Name = 'whetzel' and Initial = 's'
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063292(CHEMBL349426 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of [3H]- prazosin binding against Alpha-1A adrenergic receptor from rat submaxillary glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343274(7-(4-(4-(5,6,7,8-tetrahydronaphthalen-1-yl)piperaz...)
Affinity DataKi:  0.0900nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343260(7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...)
Affinity DataKi:  0.130nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063279(CHEMBL309623 | Cyclohexanecarboxylic acid {4-[2-(4...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343277(7-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)-3,...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of [3H]- prazosin binding against Alpha-1B adrenergic receptor from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343273(7-(4-(4-(2,3-dihydro-1H-inden-4-yl)piperazin-1-yl)...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343276(7-(4-(4-(chroman-8-yl)piperazin-1-yl)butoxy)-3,4-d...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343283(7-(4-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.280nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343268(7-(4-(4-(2,3-dimethylphenyl)piperazin-1-yl)butoxy)...)
Affinity DataKi:  0.350nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343266(7-(4-(4-(2-chloro-3-methylphenyl)piperazin-1-yl)bu...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063281((4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}...)
Affinity DataKi:  0.5nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343284(7-(4-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.670nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343276(7-(4-(4-(chroman-8-yl)piperazin-1-yl)butoxy)-3,4-d...)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343284(7-(4-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.770nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343275(7-(4-(4-(chroman-5-yl)piperazin-1-yl)butoxy)-3,4-d...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343259(7-(5-(4-(2,3-dichlorophenyl)piperazin-1-yl)pentyl)...)
Affinity DataKi:  0.790nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063291(CHEMBL78791 | Thiophene-2-carboxylic acid {4-[2-(4...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343277(7-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)-3,...)
Affinity DataKi:  0.810nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343278(7-(4-(4-(2-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM85093(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Affinity DataKi:  0.910nMAssay Description:In vitro binding affinity at human dopamine D4 receptor expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM85093(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Affinity DataKi:  0.910nMAssay Description:Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343271(7-(4-(4-(2-chloro-3-(trifluoromethyl)phenyl)pipera...)
Affinity DataKi:  0.950nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343270(7-(4-(4-(3-chloro-2-fluorophenyl)piperazin-1-yl)bu...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343282(7-(4-(4-(6-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343263(2-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343261(7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343275(7-(4-(4-(chroman-5-yl)piperazin-1-yl)butoxy)-3,4-d...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343273(7-(4-(4-(2,3-dihydro-1H-inden-4-yl)piperazin-1-yl)...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343266(7-(4-(4-(2-chloro-3-methylphenyl)piperazin-1-yl)bu...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343271(7-(4-(4-(2-chloro-3-(trifluoromethyl)phenyl)pipera...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343260(7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343283(7-(4-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343276(7-(4-(4-(chroman-8-yl)piperazin-1-yl)butoxy)-3,4-d...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343279(7-(4-(4-(3-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343282(7-(4-(4-(6-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343270(7-(4-(4-(3-chloro-2-fluorophenyl)piperazin-1-yl)bu...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343283(7-(4-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343275(7-(4-(4-(chroman-5-yl)piperazin-1-yl)butoxy)-3,4-d...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343272(7-(4-(4-(3-chloro-2-(trifluoromethyl)phenyl)pipera...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343274(7-(4-(4-(5,6,7,8-tetrahydronaphthalen-1-yl)piperaz...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343269(7-(4-(4-(3-chloro-2-methylphenyl)piperazin-1-yl)bu...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343261(7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343278(7-(4-(4-(2-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343265(7-(4-(4-(2-chloro-3-fluorophenyl)piperazin-1-yl)bu...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343284(7-(4-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50083349(6-[4-(3,4-Dimethyl-phenyl)-piperidin-1-ylmethyl]-4...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of [3H]- pentazocine binding against alpha-1 from guinea pig brainMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Displayed 1 to 50 (of 307 total ) | Next | Last >>
Jump to: