TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 240nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 690nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 2.40E+4nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 5.20E+4nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 6.10E+4nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 8.10E+4nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]- DCKA binding to NMDA receptor of rat brain membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2B NMDA receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1/2B.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Antagonist activity against rat 1A/2B subtype of N-methyl-D-aspartate(NMDA) receptor in xenopus oocytes.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]- DCKA binding to NMDA receptor of rat brain membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2B NMDA receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist activity against rat 1A/2B subtype of N-methyl-D-aspartate(NMDA) receptor in xenopus oocytes.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon
Curated by ChEMBL
University Of Oregon
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of [3H]- DCKA binding to NMDA receptor of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of [3H]- DCKA binding to NMDA receptor of rat brain membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Antagonistic activity against NR1A/2B receptor in frog oocytesMore data for this Ligand-Target Pair