Affinity DataKi: 7.10nMAssay Description:Binding affinity of the compound was tested against caspase-3 (Csp-3)More data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Binding affinity of the compound was tested against Murine caspase-1 (mCsp-1)More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Binding affinity of the compound was tested against caspase-3 (Csp-3)More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Binding affinity of the compound was tested against caspase-3 (Csp-3)More data for this Ligand-Target Pair
Affinity DataKi: 2.68E+3nMAssay Description:Binding affinity of the compound was tested against Murine caspase-1 (mCsp-1)More data for this Ligand-Target Pair
Affinity DataKi: 3.17E+3nMAssay Description:Binding affinity of the compound was tested against Murine caspase-1 (mCsp-1)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0240nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0240nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0450nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0510nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0550nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0590nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0760nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:Inhibition of active p38a MAP kinase by inhibitors was determinedusing a p38a cascade activity assay. A 30-lL reaction mixture wasprepared containing...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibitory concentration of compound required against Caspase-3 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibitory concentration of compound required against Caspase-3 compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibitory concentration of compound required against Caspase-3 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibitory concentration of compound required against Caspase-3 compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of Caspase-3More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of unactive p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of active p38alphaMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Binding of inhibitors to unactivated p38a that leads to decreasedphosphorylation of p38alpha by MKK6 was determined by measuringthe activated p38alph...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of unactive p38alphaMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibitory concentration of compound required against Caspase-1 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibitory concentration of compound required against Caspase-1 compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:Binding of inhibitors to unactivated p38a that leads to decreasedphosphorylation of p38alpha by MKK6 was determined by measuringthe activated p38alph...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Binding affinity of the compound towards human Caspase-8More data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of Caspase-8 enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:Binding of inhibitors to unactivated p38a that leads to decreasedphosphorylation of p38alpha by MKK6 was determined by measuringthe activated p38alph...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research
Curated by ChEMBL
Syntex Research
Curated by ChEMBL
Affinity DataIC50: 8.51nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration of compound required against Caspase-7 compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration of compound required against Caspase-7 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair