TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.000540nMAssay Description:Binding affinity of the compound against Opioid receptor mu 1 using [3H]-DAMGO in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.00105nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 using [3H]-DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.00260nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 using [3H]-DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.00680nMAssay Description:Binding affinity was determined towards Opioid receptor mu 1 in rat brain synaptosomes using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.0251nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Binding affinity was determined towards Opioid receptor mu 1 in rat brain synaptosomes using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.0310nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 in rat brain synaptosomes using [3H]-deltorphin II as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nM ΔG°: -58.8kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.0700nM ΔG°: -57.4kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.0920nMAssay Description:Binding affinity of the compound against Opioid receptor mu 1 using [3H]-DAMGO in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.150nM ΔG°: -55.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.158nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 in rat brain synaptosomes using [3H]-deltorphin II as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.230nM ΔG°: -54.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -52.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
TargetOxytocin receptor(Homo sapiens (Human))
Tohoku University And Department Of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University And Department Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.510nMAssay Description:Displacement of [3H]OT from recombinant human OTR expressed in HEK293 cell membranes measured after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
TargetOxytocin receptor(Homo sapiens (Human))
Tohoku University And Department Of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University And Department Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.580nMAssay Description:Displacement of [3H]OT from recombinant human OTR expressed in HEK293 cell membranes measured after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 0.610nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.650nM ΔG°: -51.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.75nM ΔG°: -51.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
TargetOxytocin receptor(Homo sapiens (Human))
Tohoku University And Department Of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University And Department Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]OT from recombinant human OTR expressed in HEK293 cell membranes measured after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
TargetOxytocin receptor(Homo sapiens (Human))
Tohoku University And Department Of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University And Department Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]OT from recombinant human OTR expressed in HEK293 cell membranes measured after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Binding affinity was determined towards Opioid receptor mu 1 in rat brain synaptosomes using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
TargetOxytocin receptor(Homo sapiens (Human))
Tohoku University And Department Of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University And Department Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]OT from recombinant human OTR expressed in HEK293 cell membranes measured after 1 hrMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 in rat brain synaptosomes using [3H]-deltorphin II as radioligand.More data for this Ligand-Target Pair
TargetOxytocin receptor(Homo sapiens (Human))
Tohoku University And Department Of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University And Department Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]OT from recombinant human OTR expressed in HEK293 cell membranes measured after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair