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Found 39 with Last Name = 'zeynalzadegan' and Initial = 'a'
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185589((E)-2-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185586((E)-4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihydr...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185592((E)-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihyd...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185601(CHEMBL380059)
Affinity DataIC50:  24nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23400((2Z)-4-(3-benzylphenyl)-2-hydroxy-4-oxobut-2-enoic...)
Affinity DataIC50:  26nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50483196(CHEMBL513189 | GS-9160)
Affinity DataIC50:  28nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetIntegrase(Human immunodeficiency virus 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM25351(N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...)
Affinity DataIC50:  34nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23399(4-{1-[(4-fluorophenyl)methyl]-1H-pyrrol-2-yl}-2,4-...)
Affinity DataIC50:  37nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185589((E)-2-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185592((E)-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihyd...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50478002(CHEMBL408699)
Affinity DataIC50:  40nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23401(6-[(3-chloro-2-fluorophenyl)methyl]-1-[(2R)-1-hydr...)
Affinity DataIC50:  42nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50:  44nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23402(5-(1,1-dioxo-1,2-thiazinan-2-yl)-N-[(4-fluoropheny...)
Affinity DataIC50:  44nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23398((2Z)-1-{5-[(4-fluorophenyl)methyl]furan-2-yl}-3-hy...)
Affinity DataIC50:  46nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23403(7-[(4-fluorophenyl)methyl]-9-hydroxy-5-methoxy-6H,...)
Affinity DataIC50:  60nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185595((E)-2-(N-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-...)
Affinity DataIC50:  68nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185586((E)-4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihydr...)
Affinity DataIC50:  71nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185585((E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihy...)
Affinity DataIC50:  86nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185590((2-{[(2E)-4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)
Affinity DataIC50:  93nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185596((E)-5-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihy...)
Affinity DataIC50:  96nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185604((E)-2-((4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-di...)
Affinity DataIC50:  132nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185603((E)-4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihy...)
Affinity DataIC50:  168nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185599((E)-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  246nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185587(7-hydroxy-5-methoxy-4-methyl-6-(3-methylbut-2-enyl...)
Affinity DataIC50:  254nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185594((E)-7-hydroxy-5-methoxy-6-(4-methoxy-3-methylbut-2...)
Affinity DataIC50:  273nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185588((E)-dimethyl 4-(4-hydroxy-6-methoxy-7-methyl-3-oxo...)
Affinity DataIC50:  289nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185598((2-{[(E)-4-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3...)
Affinity DataIC50:  498nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185602((E)-2-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-d...)
Affinity DataIC50:  499nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185600((1E,3E)-5-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-...)
Affinity DataIC50:  506nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185597((E)-2-(N-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)
Affinity DataIC50:  749nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185583((E)-2-(N-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)
Affinity DataIC50:  785nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185593((E)-diethyl 2-(4-(4-hydroxy-6-methoxy-7-methyl-3-o...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185584((E)-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185591((E)-2-((4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23405(7-[(4-fluorophenyl)methyl]-5-methoxy-6H,7H,8H-pyrr...)
Affinity DataIC50:  2.40E+4nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM23404(7-[(4-fluorophenyl)methyl]-5,9-dimethoxy-6H,7H,8H-...)
Affinity DataIC50: >1.00E+6nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed