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80 similar compounds to monomer 144086

Compile data set for download or QSAR
Wt: 485.4
BDBM144010
Wt: 419.3
BDBM144012
Wt: 437.3
BDBM144013
Wt: 401.4
BDBM144014
Wt: 419.3
BDBM144015
Wt: 435.8
BDBM144016
Wt: 433.4
BDBM144017
Wt: 383.4
BDBM144018
Wt: 337.3
BDBM144019
Wt: 383.4
BDBM144020
Wt: 411.4
BDBM144021
Wt: 393.4
BDBM144022
Wt: 461.4
BDBM144023
Wt: 469.4
BDBM144119
Wt: 427.9
BDBM144024
Displayed 1 to 15 (of 80 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 144010,144012,144013,144014,144015,144016,144017,144018,144019,144020,144021,144022,144023,144119,144024   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144010
PNG
(US8969325, 211)
Show SMILES FCC1(CF)C[C@@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2ccc(OC(F)(F)F)cc2O1
Show InChI InChI=1S/C22H20F5N3O4/c23-10-21(11-24)9-17(15-5-4-14(8-18(15)34-21)33-22(25,26)27)30-20(32)28-13-3-1-12-2-6-19(31)29-16(12)7-13/h1,3-5,7-8,17H,2,6,9-11H2,(H,29,31)(H2,28,30,32)/t17-/m1/s1
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AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144024
PNG
(US8969325, 225)
Show SMILES CCC1(CC)C[C@@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2ccc(Cl)cc2O1
Show InChI InChI=1S/C23H26ClN3O3/c1-3-23(4-2)13-19(17-9-7-15(24)11-20(17)30-23)27-22(29)25-16-8-5-14-6-10-21(28)26-18(14)12-16/h5,7-9,11-12,19H,3-4,6,10,13H2,1-2H3,(H,26,28)(H2,25,27,29)/t19-/m1/s1
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AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144013
PNG
(US8969325, 214)
Show SMILES FCC1(CF)C[C@@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2cc(F)cc(F)c2O1
Show InChI InChI=1S/C21H19F4N3O3/c22-9-21(10-23)8-17(14-5-12(24)6-15(25)19(14)31-21)28-20(30)26-13-3-1-11-2-4-18(29)27-16(11)7-13/h1,3,5-7,17H,2,4,8-10H2,(H,27,29)(H2,26,28,30)/t17-/m1/s1
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n/an/a 180n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144014
PNG
(US8969325, 215)
Show SMILES FCC1(CF)C[C@@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2ccccc2O1
Show InChI InChI=1S/C21H21F2N3O3/c22-11-21(12-23)10-17(15-3-1-2-4-18(15)29-21)26-20(28)24-14-7-5-13-6-8-19(27)25-16(13)9-14/h1-5,7,9,17H,6,8,10-12H2,(H,25,27)(H2,24,26,28)/t17-/m1/s1
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n/an/a 60n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144015
PNG
(US8969325, 216)
Show SMILES FCC1(CF)C[C@@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2cccc(F)c2O1
Show InChI InChI=1S/C21H20F3N3O3/c22-10-21(11-23)9-17(14-2-1-3-15(24)19(14)30-21)27-20(29)25-13-6-4-12-5-7-18(28)26-16(12)8-13/h1-4,6,8,17H,5,7,9-11H2,(H,26,28)(H2,25,27,29)/t17-/m1/s1
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n/an/a 220n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144016
PNG
(US8969325, 217)
Show SMILES FCC1(CF)C[C@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2ccc(Cl)cc2O1
Show InChI InChI=1S/C21H20ClF2N3O3/c22-13-3-5-15-17(9-21(10-23,11-24)30-18(15)7-13)27-20(29)25-14-4-1-12-2-6-19(28)26-16(12)8-14/h1,3-5,7-8,17H,2,6,9-11H2,(H,26,28)(H2,25,27,29)/t17-/m0/s1
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n/an/a 430n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144017
PNG
(US8969325, 218)
Show SMILES CC1(C)C[C@@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2cccc(c2O1)C(F)(F)F
Show InChI InChI=1S/C22H22F3N3O3/c1-21(2)11-17(14-4-3-5-15(19(14)31-21)22(23,24)25)28-20(30)26-13-8-6-12-7-9-18(29)27-16(12)10-13/h3-6,8,10,17H,7,9,11H2,1-2H3,(H,27,29)(H2,26,28,30)/t17-/m1/s1
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n/an/a 3.60E+3n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144018
PNG
(US8969325, 219)
Show SMILES CC1(C)C[C@@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2cccc(F)c2O1
Show InChI InChI=1S/C21H22FN3O3/c1-21(2)11-17(14-4-3-5-15(22)19(14)28-21)25-20(27)23-13-8-6-12-7-9-18(26)24-16(12)10-13/h3-6,8,10,17H,7,9,11H2,1-2H3,(H,24,26)(H2,23,25,27)/t17-/m1/s1
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n/an/a 56n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144019
PNG
(US8969325, 220)
Show SMILES O=C(N[C@@H]1CCOc2ccccc12)Nc1ccc2CCC(=O)Nc2c1
Show InChI InChI=1S/C19H19N3O3/c23-18-8-6-12-5-7-13(11-16(12)21-18)20-19(24)22-15-9-10-25-17-4-2-1-3-14(15)17/h1-5,7,11,15H,6,8-10H2,(H,21,23)(H2,20,22,24)/t15-/m1/s1
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n/an/a 190n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144020
PNG
(US8969325, 221)
Show SMILES CC1(C)C[C@@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2ccc(F)cc2O1
Show InChI InChI=1S/C21H22FN3O3/c1-21(2)11-17(15-7-5-13(22)9-18(15)28-21)25-20(27)23-14-6-3-12-4-8-19(26)24-16(12)10-14/h3,5-7,9-10,17H,4,8,11H2,1-2H3,(H,24,26)(H2,23,25,27)/t17-/m1/s1
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n/an/a 1.60E+3n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144021
PNG
(US8969325, 222)
Show SMILES CCC1(CC)C[C@@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2cccc(F)c2O1
Show InChI InChI=1S/C23H26FN3O3/c1-3-23(4-2)13-19(16-6-5-7-17(24)21(16)30-23)27-22(29)25-15-10-8-14-9-11-20(28)26-18(14)12-15/h5-8,10,12,19H,3-4,9,11,13H2,1-2H3,(H,26,28)(H2,25,27,29)/t19-/m1/s1
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n/an/a 32n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144022
PNG
(US8969325, 223)
Show SMILES CCC1(CC)C[C@@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2ccccc2O1
Show InChI InChI=1S/C23H27N3O3/c1-3-23(4-2)14-19(17-7-5-6-8-20(17)29-23)26-22(28)24-16-11-9-15-10-12-21(27)25-18(15)13-16/h5-9,11,13,19H,3-4,10,12,14H2,1-2H3,(H,25,27)(H2,24,26,28)/t19-/m1/s1
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n/an/a 37n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144023
PNG
(US8969325, 224)
Show SMILES CCC1(CC)C[C@@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2ccc(cc2O1)C(F)(F)F
Show InChI InChI=1S/C24H26F3N3O3/c1-3-23(4-2)13-19(17-9-7-15(24(25,26)27)11-20(17)33-23)30-22(32)28-16-8-5-14-6-10-21(31)29-18(14)12-16/h5,7-9,11-12,19H,3-4,6,10,13H2,1-2H3,(H,29,31)(H2,28,30,32)/t19-/m1/s1
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n/an/a 35n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144119
PNG
(US8969325, 320)
Show SMILES FCC1(CF)C[C@@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2ccc(cc2O1)C(F)(F)F
Show InChI InChI=1S/C22H20F5N3O3/c23-10-21(11-24)9-17(15-5-3-13(22(25,26)27)7-18(15)33-21)30-20(32)28-14-4-1-12-2-6-19(31)29-16(12)8-14/h1,3-5,7-8,17H,2,6,9-11H2,(H,29,31)(H2,28,30,32)/t17-/m1/s1
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n/an/a 12n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM144012
PNG
(US8969325, 213)
Show SMILES FCC1(CF)C[C@@H](NC(=O)Nc2ccc3CCC(=O)Nc3c2)c2cc(F)ccc2O1
Show InChI InChI=1S/C21H20F3N3O3/c22-10-21(11-23)9-17(15-7-13(24)3-5-18(15)30-21)27-20(29)25-14-4-1-12-2-6-19(28)26-16(12)8-14/h1,3-5,7-8,17H,2,6,9-11H2,(H,26,28)(H2,25,27,29)/t17-/m1/s1
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n/an/a 170n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair