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10 similar compounds to monomer 190372

Compile data set for download or QSAR
Wt: 233.2
BDBM190366
Wt: 267.7
BDBM190367
Wt: 247.3
BDBM190368
Wt: 247.3
BDBM190369
Wt: 267.7
BDBM190370
Wt: 247.3
BDBM190371
Wt: 247.3
BDBM190374
Wt: 251.2
BDBM190376
Wt: 261.3
BDBM190377
Wt: 263.3
BDBM190386

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 190366,190367,190368,190369,190370,190371,190374,190376,190377,190386   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM190366
PNG
(US9180122, 1)
Show SMILES Oc1cc(SCc2ccccc2)c[nH]c1=O
Show InChI InChI=1S/C12H11NO2S/c14-11-6-10(7-13-12(11)15)16-8-9-4-2-1-3-5-9/h1-7,14H,8H2,(H,13,15)
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US Patent
n/an/a 190n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US9180122 (2015)


BindingDB Entry DOI: 10.7270/Q2FT8JTB
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM190367
PNG
(US9180122, 2)
Show SMILES Oc1cc(SCc2ccc(Cl)cc2)c[nH]c1=O
Show InChI InChI=1S/C12H10ClNO2S/c13-9-3-1-8(2-4-9)7-17-10-5-11(15)12(16)14-6-10/h1-6,15H,7H2,(H,14,16)
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US Patent
n/an/a 35n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US9180122 (2015)


BindingDB Entry DOI: 10.7270/Q2FT8JTB
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM190368
PNG
(US9180122, 3)
Show SMILES Cc1ccc(CSc2c[nH]c(=O)c(O)c2)cc1
Show InChI InChI=1S/C13H13NO2S/c1-9-2-4-10(5-3-9)8-17-11-6-12(15)13(16)14-7-11/h2-7,15H,8H2,1H3,(H,14,16)
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US Patent
n/an/a 29n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US9180122 (2015)


BindingDB Entry DOI: 10.7270/Q2FT8JTB
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM190369
PNG
(US9180122, 4)
Show SMILES Cc1cccc(CSc2c[nH]c(=O)c(O)c2)c1
Show InChI InChI=1S/C13H13NO2S/c1-9-3-2-4-10(5-9)8-17-11-6-12(15)13(16)14-7-11/h2-7,15H,8H2,1H3,(H,14,16)
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US Patent
n/an/a 240n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US9180122 (2015)


BindingDB Entry DOI: 10.7270/Q2FT8JTB
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM190386
PNG
(US9180122, 21)
Show SMILES COc1ccc(CSc2c[nH]c(=O)c(O)c2)cc1
Show InChI InChI=1S/C13H13NO3S/c1-17-10-4-2-9(3-5-10)8-18-11-6-12(15)13(16)14-7-11/h2-7,15H,8H2,1H3,(H,14,16)
PDB
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US Patent
n/an/a 130n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US9180122 (2015)


BindingDB Entry DOI: 10.7270/Q2FT8JTB
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM190371
PNG
(US9180122, 6)
Show SMILES CC(Sc1c[nH]c(=O)c(O)c1)c1ccccc1
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n/an/a 1.30E+3n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US9180122 (2015)


BindingDB Entry DOI: 10.7270/Q2FT8JTB
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM190374
PNG
(US9180122, 9)
Show SMILES Cc1ccccc1CSc1c[nH]c(=O)c(O)c1
Show InChI InChI=1S/C13H13NO2S/c1-9-4-2-3-5-10(9)8-17-11-6-12(15)13(16)14-7-11/h2-7,15H,8H2,1H3,(H,14,16)
PDB
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US Patent
n/an/a 390n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US9180122 (2015)


BindingDB Entry DOI: 10.7270/Q2FT8JTB
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM190376
PNG
(US9180122, 11)
Show SMILES Oc1cc(SCc2ccc(F)cc2)c[nH]c1=O
Show InChI InChI=1S/C12H10FNO2S/c13-9-3-1-8(2-4-9)7-17-10-5-11(15)12(16)14-6-10/h1-6,15H,7H2,(H,14,16)
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US Patent
n/an/a 47n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US9180122 (2015)


BindingDB Entry DOI: 10.7270/Q2FT8JTB
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM190377
PNG
(US9180122, 12)
Show SMILES CCc1ccc(CSc2c[nH]c(=O)c(O)c2)cc1
Show InChI InChI=1S/C14H15NO2S/c1-2-10-3-5-11(6-4-10)9-18-12-7-13(16)14(17)15-8-12/h3-8,16H,2,9H2,1H3,(H,15,17)
PDB
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US Patent
n/an/a 79n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US9180122 (2015)


BindingDB Entry DOI: 10.7270/Q2FT8JTB
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM190370
PNG
(US9180122, 5)
Show SMILES Oc1cc(SCc2cccc(Cl)c2)c[nH]c1=O
Show InChI InChI=1S/C12H10ClNO2S/c13-9-3-1-2-8(4-9)7-17-10-5-11(15)12(16)14-6-10/h1-6,15H,7H2,(H,14,16)
PDB
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US Patent
n/an/a 55n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US9180122 (2015)


BindingDB Entry DOI: 10.7270/Q2FT8JTB
More data for this
Ligand-Target Pair