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12 similar compounds to monomer 78463

Compile data set for download or QSAR
Wt: 383.8
BDBM34530
Purchase
Wt: 349.3
BDBM55409
Purchase
Wt: 375.7
BDBM78451
Wt: 357.7
BDBM78452
Wt: 341.3
BDBM78454
Wt: 367.3
BDBM78462
Wt: 383.8
BDBM78464
Wt: 401.8
BDBM78465
Wt: 367.3
BDBM78466
Wt: 363.4
BDBM78467
Wt: 397.7
BDBM78475
Wt: 365.7
BDBM78482

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 34530,55409,78451,78452,78454,78462,78464,78465,78466,78467,78475,78482   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ubiquitin-conjugating enzyme E2I


(Homo sapiens (Human))
BDBM34530
PNG
(2-(4-chloranylphenoxy)-N-[5-(5,6,7,8-tetrahydronap...)
Show SMILES Clc1ccc(OCC(=O)Nc2nnc(o2)-c2ccc3CCCCc3c2)cc1
Show InChI InChI=1S/C20H18ClN3O3/c21-16-7-9-17(10-8-16)26-12-18(25)22-20-24-23-19(27-20)15-6-5-13-3-1-2-4-14(13)11-15/h5-11H,1-4,12H2,(H,22,24,25)
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n/an/a 1.00E+5n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2V986G8
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM55409
PNG
(2-phenoxy-N-(5-tetralin-6-yl-1,3,4-oxadiazol-2-yl)...)
Show SMILES O=C(COc1ccccc1)Nc1nnc(o1)-c1ccc2CCCCc2c1
Show InChI InChI=1S/C20H19N3O3/c24-18(13-25-17-8-2-1-3-9-17)21-20-23-22-19(26-20)16-11-10-14-6-4-5-7-15(14)12-16/h1-3,8-12H,4-7,13H2,(H,21,23,24)
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n/an/an/an/a 1.71E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
SUMO1 activating enzyme subunit 1


(Homo sapiens (Human))
BDBM34530
PNG
(2-(4-chloranylphenoxy)-N-[5-(5,6,7,8-tetrahydronap...)
Show SMILES Clc1ccc(OCC(=O)Nc2nnc(o2)-c2ccc3CCCCc3c2)cc1
Show InChI InChI=1S/C20H18ClN3O3/c21-16-7-9-17(10-8-16)26-12-18(25)22-20-24-23-19(27-20)15-6-5-13-3-1-2-4-14(13)11-15/h5-11H,1-4,12H2,(H,22,24,25)
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n/an/a 4.83E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2BP0175
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM55409
PNG
(2-phenoxy-N-(5-tetralin-6-yl-1,3,4-oxadiazol-2-yl)...)
Show SMILES O=C(COc1ccccc1)Nc1nnc(o1)-c1ccc2CCCCc2c1
Show InChI InChI=1S/C20H19N3O3/c24-18(13-25-17-8-2-1-3-9-17)21-20-23-22-19(26-20)16-11-10-14-6-4-5-7-15(14)12-16/h1-3,8-12H,4-7,13H2,(H,21,23,24)
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n/an/an/an/a 2.51E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q29885H0
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM78451
PNG
(2-(2-chloranyl-4-fluoranyl-phenoxy)-N-[5-(3,4-dime...)
Show SMILES Cc1ccc(cc1C)-c1nnc(NC(=O)COc2ccc(F)cc2Cl)o1
Show InChI InChI=1S/C18H15ClFN3O3/c1-10-3-4-12(7-11(10)2)17-22-23-18(26-17)21-16(24)9-25-15-6-5-13(20)8-14(15)19/h3-8H,9H2,1-2H3,(H,21,23,24)
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n/an/an/an/a 1.10E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q25M645J
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM78452
PNG
(2-(2-chloranylphenoxy)-N-[5-(3,4-dimethylphenyl)-1...)
Show SMILES Cc1ccc(cc1C)-c1nnc(NC(=O)COc2ccccc2Cl)o1
Show InChI InChI=1S/C18H16ClN3O3/c1-11-7-8-13(9-12(11)2)17-21-22-18(25-17)20-16(23)10-24-15-6-4-3-5-14(15)19/h3-9H,10H2,1-2H3,(H,20,22,23)
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n/an/an/an/a 1.30E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q25M645J
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM78454
PNG
(N-[5-(3,4-dimethylphenyl)-1,3,4-oxadiazol-2-yl]-2-...)
Show SMILES Cc1ccc(cc1C)-c1nnc(NC(=O)COc2ccc(F)cc2)o1
Show InChI InChI=1S/C18H16FN3O3/c1-11-3-4-13(9-12(11)2)17-21-22-18(25-17)20-16(23)10-24-15-7-5-14(19)6-8-15/h3-9H,10H2,1-2H3,(H,20,22,23)
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n/an/an/an/a 1.00E+4n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q25M645J
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM78462
PNG
(2-(2-fluoranylphenoxy)-N-[5-(5,6,7,8-tetrahydronap...)
Show SMILES Fc1ccccc1OCC(=O)Nc1nnc(o1)-c1ccc2CCCCc2c1
Show InChI InChI=1S/C20H18FN3O3/c21-16-7-3-4-8-17(16)26-12-18(25)22-20-24-23-19(27-20)15-10-9-13-5-1-2-6-14(13)11-15/h3-4,7-11H,1-2,5-6,12H2,(H,22,24,25)
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n/an/an/an/a 1.70E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q25M645J
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM78464
PNG
(2-(2-chloranylphenoxy)-N-[5-(5,6,7,8-tetrahydronap...)
Show SMILES Clc1ccccc1OCC(=O)Nc1nnc(o1)-c1ccc2CCCCc2c1
Show InChI InChI=1S/C20H18ClN3O3/c21-16-7-3-4-8-17(16)26-12-18(25)22-20-24-23-19(27-20)15-10-9-13-5-1-2-6-14(13)11-15/h3-4,7-11H,1-2,5-6,12H2,(H,22,24,25)
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n/an/an/an/a 1.00E+4n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q25M645J
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM78465
PNG
(2-(3-chloranyl-4-fluoranyl-phenoxy)-N-[5-(5,6,7,8-...)
Show SMILES Fc1ccc(OCC(=O)Nc2nnc(o2)-c2ccc3CCCCc3c2)cc1Cl
Show InChI InChI=1S/C20H17ClFN3O3/c21-16-10-15(7-8-17(16)22)27-11-18(26)23-20-25-24-19(28-20)14-6-5-12-3-1-2-4-13(12)9-14/h5-10H,1-4,11H2,(H,23,25,26)
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n/an/an/an/a 2.40E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q25M645J
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM78466
PNG
(2-(4-fluoranylphenoxy)-N-[5-(5,6,7,8-tetrahydronap...)
Show SMILES Fc1ccc(OCC(=O)Nc2nnc(o2)-c2ccc3CCCCc3c2)cc1
Show InChI InChI=1S/C20H18FN3O3/c21-16-7-9-17(10-8-16)26-12-18(25)22-20-24-23-19(27-20)15-6-5-13-3-1-2-4-14(13)11-15/h5-11H,1-4,12H2,(H,22,24,25)
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n/an/an/an/a 2.10E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q25M645J
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM78467
PNG
(2-phenoxy-N-(5-tetralin-6-yl-1,3,4-oxadiazol-2-yl)...)
Show SMILES CC(Oc1ccccc1)C(=O)Nc1nnc(o1)-c1ccc2CCCCc2c1
Show InChI InChI=1S/C21H21N3O3/c1-14(26-18-9-3-2-4-10-18)19(25)22-21-24-23-20(27-21)17-12-11-15-7-5-6-8-16(15)13-17/h2-4,9-14H,5-8H2,1H3,(H,22,24,25)
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n/an/an/an/a 1.30E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q25M645J
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM34530
PNG
(2-(4-chloranylphenoxy)-N-[5-(5,6,7,8-tetrahydronap...)
Show SMILES Clc1ccc(OCC(=O)Nc2nnc(o2)-c2ccc3CCCCc3c2)cc1
Show InChI InChI=1S/C20H18ClN3O3/c21-16-7-9-17(10-8-16)26-12-18(25)22-20-24-23-19(27-20)15-6-5-13-3-1-2-4-14(13)11-15/h5-11H,1-4,12H2,(H,22,24,25)
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n/an/an/an/a 2.80E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q25M645J
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM78475
PNG
(2-(2-chloranyl-4-fluoranyl-phenoxy)-N-(5-naphthale...)
Show SMILES Fc1ccc(OCC(=O)Nc2nnc(o2)-c2ccc3ccccc3c2)c(Cl)c1
Show InChI InChI=1S/C20H13ClFN3O3/c21-16-10-15(22)7-8-17(16)27-11-18(26)23-20-25-24-19(28-20)14-6-5-12-3-1-2-4-13(12)9-14/h1-10H,11H2,(H,23,25,26)
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n/an/an/an/a 3.60E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q25M645J
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM78482
PNG
(2-(2-chloranyl-4-fluoranyl-phenoxy)-N-[5-(4-fluoro...)
Show SMILES Fc1ccc(cc1)-c1nnc(NC(=O)COc2ccc(F)cc2Cl)o1
Show InChI InChI=1S/C16H10ClF2N3O3/c17-12-7-11(19)5-6-13(12)24-8-14(23)20-16-22-21-15(25-16)9-1-3-10(18)4-2-9/h1-7H,8H2,(H,20,22,23)
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n/an/an/an/a 1.90E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q25M645J
More data for this
Ligand-Target Pair
neutrophil cytosolic factor 1


(Homo sapiens (Human))
BDBM55409
PNG
(2-phenoxy-N-(5-tetralin-6-yl-1,3,4-oxadiazol-2-yl)...)
Show SMILES O=C(COc1ccccc1)Nc1nnc(o1)-c1ccc2CCCCc2c1
Show InChI InChI=1S/C20H19N3O3/c24-18(13-25-17-8-2-1-3-9-17)21-20-23-22-19(26-20)16-11-10-14-6-4-5-7-15(14)12-16/h1-3,8-12H,4-7,13H2,(H,21,23,24)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Emory University

Curated by PubChem BioAssay


Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2M90723
More data for this
Ligand-Target Pair