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32 similar compounds to monomer 50187066

Compile data set for download or QSAR
Wt: 308.3
BDBM40431
Purchase
Wt: 423.6
BDBM59547
Purchase
Wt: 308.2
BDBM72822
Purchase
Wt: 423.6
BDBM88959
Wt: 439.2
BDBM50187572
Wt: 379.1
BDBM50187069
Wt: 333.1
BDBM50278597
Purchase
Wt: 349.1
BDBM50278598
Wt: 367.6
BDBM50278599
Purchase
Wt: 363.1
BDBM50278600
Wt: 363.1
BDBM50278601
Wt: 363.1
BDBM50278602
Wt: 367.6
BDBM50278636
Wt: 379.1
BDBM50278638
Wt: 393.2
BDBM50278639
Displayed 1 to 15 (of 32 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 40431,59547,72822,88959,50187572,50187069,50278597,50278598,50278599,50278600,50278601,50278602,50278636,50278638,50278639   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase ABL1


(Homo sapiens (Human))
BDBM50187572
PNG
(4-(3-(benzyloxy)benzylidene)-1-(3,4-dichlorophenyl...)
Show SMILES Clc1ccc(cc1Cl)N1NC(=O)C(=Cc2cccc(OCc3ccccc3)c2)C1=O
Show InChI InChI=1S/C23H16Cl2N2O3/c24-20-10-9-17(13-21(20)25)27-23(29)19(22(28)26-27)12-16-7-4-8-18(11-16)30-14-15-5-2-1-3-6-15/h1-13H,14H2,(H,26,28)
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PubMed
1.00E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant Abl


J Med Chem 49: 3278-86 (2006)


Article DOI: 10.1021/jm060236z
BindingDB Entry DOI: 10.7270/Q2TH8M9R
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50187572
PNG
(4-(3-(benzyloxy)benzylidene)-1-(3,4-dichlorophenyl...)
Show SMILES Clc1ccc(cc1Cl)N1NC(=O)C(=Cc2cccc(OCc3ccccc3)c2)C1=O
Show InChI InChI=1S/C23H16Cl2N2O3/c24-20-10-9-17(13-21(20)25)27-23(29)19(22(28)26-27)12-16-7-4-8-18(11-16)30-14-15-5-2-1-3-6-15/h1-13H,14H2,(H,26,28)
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5.40E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant Src


J Med Chem 49: 3278-86 (2006)


Article DOI: 10.1021/jm060236z
BindingDB Entry DOI: 10.7270/Q2TH8M9R
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM40431
PNG
((4Z)-4-[(3-methoxyphenyl)methylidene]-1-(4-methylp...)
Show SMILES COc1cccc(\C=C2\C(=O)NN(C2=O)c2ccc(C)cc2)c1
Show InChI InChI=1S/C18H16N2O3/c1-12-6-8-14(9-7-12)20-18(22)16(17(21)19-20)11-13-4-3-5-15(10-13)23-2/h3-11H,1-2H3,(H,19,21)/b16-11-
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>4.03E+4n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q26M3571
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (Human))
BDBM40431
PNG
((4Z)-4-[(3-methoxyphenyl)methylidene]-1-(4-methylp...)
Show SMILES COc1cccc(\C=C2\C(=O)NN(C2=O)c2ccc(C)cc2)c1
Show InChI InChI=1S/C18H16N2O3/c1-12-6-8-14(9-7-12)20-18(22)16(17(21)19-20)11-13-4-3-5-15(10-13)23-2/h3-11H,1-2H3,(H,19,21)/b16-11-
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>4.43E+4n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2Z31X1B
More data for this
Ligand-Target Pair
Tumor necrosis factor


(Homo sapiens (Human))
BDBM59547
PNG
((4Z)-4-(3-bromo-4-hydroxy-5-methoxy-benzylidene)-1...)
Show SMILES COc1cc(\C=C2\C(=O)NN(C2=O)c2cccc(Cl)c2)cc(Br)c1O
Show InChI InChI=1S/C17H12BrClN2O4/c1-25-14-7-9(6-13(18)15(14)22)5-12-16(23)20-21(17(12)24)11-4-2-3-10(19)8-11/h2-8,22H,1H3,(H,20,23)/b12-5-
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n/an/a>2.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2PR7TDC
More data for this
Ligand-Target Pair
Tumor necrosis factor


(Homo sapiens (Human))
BDBM59547
PNG
((4Z)-4-(3-bromo-4-hydroxy-5-methoxy-benzylidene)-1...)
Show SMILES COc1cc(\C=C2\C(=O)NN(C2=O)c2cccc(Cl)c2)cc(Br)c1O
Show InChI InChI=1S/C17H12BrClN2O4/c1-25-14-7-9(6-13(18)15(14)22)5-12-16(23)20-21(17(12)24)11-4-2-3-10(19)8-11/h2-8,22H,1H3,(H,20,23)/b12-5-
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n/an/a 2.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


Article DOI: 10.1002/cbic.201402089
BindingDB Entry DOI: 10.7270/Q25M6443
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM59547
PNG
((4Z)-4-(3-bromo-4-hydroxy-5-methoxy-benzylidene)-1...)
Show SMILES COc1cc(\C=C2\C(=O)NN(C2=O)c2cccc(Cl)c2)cc(Br)c1O
Show InChI InChI=1S/C17H12BrClN2O4/c1-25-14-7-9(6-13(18)15(14)22)5-12-16(23)20-21(17(12)24)11-4-2-3-10(19)8-11/h2-8,22H,1H3,(H,20,23)/b12-5-
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n/an/an/an/a 4.26E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Hsf1 protein


(Mus musculus)
BDBM72822
PNG
((4Z)-1-phenyl-4-piperonylidene-pyrazolidine-3,5-qu...)
Show SMILES O=C1NN(C(=O)\C1=C/c1ccc2OCOc2c1)c1ccccc1
Show InChI InChI=1S/C17H12N2O4/c20-16-13(8-11-6-7-14-15(9-11)23-10-22-14)17(21)19(18-16)12-4-2-1-3-5-12/h1-9H,10H2,(H,18,20)/b13-8-
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n/an/an/an/a>2.60E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2P55KXK
More data for this
Ligand-Target Pair
Thrombin


(Bos taurus (Bovine))
BDBM88959
PNG
((4Z)-4-(3-bromo-4-hydroxy-5-methoxy-benzylidene)-1...)
Show SMILES COc1cc(\C=C2\C(=O)NN(C2=O)c2ccc(Cl)cc2)cc(Br)c1O
Show InChI InChI=1S/C17H12BrClN2O4/c1-25-14-8-9(7-13(18)15(14)22)6-12-16(23)20-21(17(12)24)11-4-2-10(19)3-5-11/h2-8,22H,1H3,(H,20,23)/b12-6-
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n/an/a 6.06E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2JM286J
More data for this
Ligand-Target Pair
26S Proteasome regulatory subunit Rpn11 (Rpn11)


(Homo sapiens (Human))
BDBM88959
PNG
((4Z)-4-(3-bromo-4-hydroxy-5-methoxy-benzylidene)-1...)
Show SMILES COc1cc(\C=C2\C(=O)NN(C2=O)c2ccc(Cl)cc2)cc(Br)c1O
Show InChI InChI=1S/C17H12BrClN2O4/c1-25-14-8-9(7-13(18)15(14)22)6-12-16(23)20-21(17(12)24)11-4-2-10(19)3-5-11/h2-8,22H,1H3,(H,20,23)/b12-6-
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n/an/a 1.45E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2PC30Z9
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Homo sapiens (Human))
BDBM50278598
PNG
(1-(3,4-dichlorophenyl)-4-(4-hydroxybenzylidene)pyr...)
Show SMILES Oc1ccc(C=C2C(=O)NN(C2=O)c2ccc(Cl)c(Cl)c2)cc1
Show InChI InChI=1S/C16H10Cl2N2O3/c17-13-6-3-10(8-14(13)18)20-16(23)12(15(22)19-20)7-9-1-4-11(21)5-2-9/h1-8,21H,(H,19,22)
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n/an/a 2.50E+3n/an/an/an/an/an/a



Inje University

Curated by ChEMBL


Assay Description
Inhibition of Dyrk1 (unknown origin) autophosphorylation


Bioorg Med Chem Lett 19: 2324-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.062
BindingDB Entry DOI: 10.7270/Q2SN08VT
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Homo sapiens (Human))
BDBM50278599
PNG
(4-(4-chlorobenzylidene)-1-(3,4-dichlorophenyl)pyra...)
Show SMILES Clc1ccc(C=C2C(=O)NN(C2=O)c2ccc(Cl)c(Cl)c2)cc1
Show InChI InChI=1S/C16H9Cl3N2O2/c17-10-3-1-9(2-4-10)7-12-15(22)20-21(16(12)23)11-5-6-13(18)14(19)8-11/h1-8H,(H,20,22)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Inje University

Curated by ChEMBL


Assay Description
Inhibition of Dyrk1 (unknown origin) autophosphorylation


Bioorg Med Chem Lett 19: 2324-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.062
BindingDB Entry DOI: 10.7270/Q2SN08VT
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Homo sapiens (Human))
BDBM50278600
PNG
(1-(3,4-dichlorophenyl)-4-(4-methoxybenzylidene)pyr...)
Show SMILES COc1ccc(C=C2C(=O)NN(C2=O)c2ccc(Cl)c(Cl)c2)cc1
Show InChI InChI=1S/C17H12Cl2N2O3/c1-24-12-5-2-10(3-6-12)8-13-16(22)20-21(17(13)23)11-4-7-14(18)15(19)9-11/h2-9H,1H3,(H,20,22)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Inje University

Curated by ChEMBL


Assay Description
Inhibition of Dyrk1 (unknown origin) autophosphorylation


Bioorg Med Chem Lett 19: 2324-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.062
BindingDB Entry DOI: 10.7270/Q2SN08VT
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Homo sapiens (Human))
BDBM50278601
PNG
(1-(3,4-dichlorophenyl)-4-(3-methoxybenzylidene)pyr...)
Show SMILES COc1cccc(C=C2C(=O)NN(C2=O)c2ccc(Cl)c(Cl)c2)c1
Show InChI InChI=1S/C17H12Cl2N2O3/c1-24-12-4-2-3-10(7-12)8-13-16(22)20-21(17(13)23)11-5-6-14(18)15(19)9-11/h2-9H,1H3,(H,20,22)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Inje University

Curated by ChEMBL


Assay Description
Inhibition of Dyrk1 (unknown origin) autophosphorylation


Bioorg Med Chem Lett 19: 2324-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.062
BindingDB Entry DOI: 10.7270/Q2SN08VT
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Homo sapiens (Human))
BDBM50278602
PNG
(1-(3,4-dichlorophenyl)-4-(2-methoxybenzylidene)pyr...)
Show SMILES COc1ccccc1C=C1C(=O)NN(C1=O)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C17H12Cl2N2O3/c1-24-15-5-3-2-4-10(15)8-12-16(22)20-21(17(12)23)11-6-7-13(18)14(19)9-11/h2-9H,1H3,(H,20,22)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Inje University

Curated by ChEMBL


Assay Description
Inhibition of Dyrk1 (unknown origin) autophosphorylation


Bioorg Med Chem Lett 19: 2324-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.062
BindingDB Entry DOI: 10.7270/Q2SN08VT
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Homo sapiens (Human))
BDBM50278636
PNG
(4-(2-chlorobenzylidene)-1-(3,4-dichlorophenyl)pyra...)
Show SMILES Clc1ccc(cc1Cl)N1NC(=O)C(=Cc2ccccc2Cl)C1=O
Show InChI InChI=1S/C16H9Cl3N2O2/c17-12-4-2-1-3-9(12)7-11-15(22)20-21(16(11)23)10-5-6-13(18)14(19)8-10/h1-8H,(H,20,22)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Inje University

Curated by ChEMBL


Assay Description
Inhibition of Dyrk1 (unknown origin) autophosphorylation


Bioorg Med Chem Lett 19: 2324-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.062
BindingDB Entry DOI: 10.7270/Q2SN08VT
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Homo sapiens (Human))
BDBM50278638
PNG
(1-(3,4-dichlorophenyl)-4-(3-hydroxy-4-methoxybenzy...)
Show SMILES COc1ccc(C=C2C(=O)NN(C2=O)c2ccc(Cl)c(Cl)c2)cc1O
Show InChI InChI=1S/C17H12Cl2N2O4/c1-25-15-5-2-9(7-14(15)22)6-11-16(23)20-21(17(11)24)10-3-4-12(18)13(19)8-10/h2-8,22H,1H3,(H,20,23)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Inje University

Curated by ChEMBL


Assay Description
Inhibition of Dyrk1 (unknown origin) autophosphorylation


Bioorg Med Chem Lett 19: 2324-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.062
BindingDB Entry DOI: 10.7270/Q2SN08VT
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Homo sapiens (Human))
BDBM50278639
PNG
(1-(3,4-dichlorophenyl)-4-(3,4-dimethoxybenzylidene...)
Show SMILES COc1ccc(C=C2C(=O)NN(C2=O)c2ccc(Cl)c(Cl)c2)cc1OC
Show InChI InChI=1S/C18H14Cl2N2O4/c1-25-15-6-3-10(8-16(15)26-2)7-12-17(23)21-22(18(12)24)11-4-5-13(19)14(20)9-11/h3-9H,1-2H3,(H,21,23)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Inje University

Curated by ChEMBL


Assay Description
Inhibition of Dyrk1 (unknown origin) autophosphorylation


Bioorg Med Chem Lett 19: 2324-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.062
BindingDB Entry DOI: 10.7270/Q2SN08VT
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Homo sapiens (Human))
BDBM50187069
PNG
(1-(3,4-dichlorophenyl)-4-(4-hydroxy-3-methoxybenzy...)
Show SMILES COc1cc(C=C2C(=O)NN(C2=O)c2ccc(Cl)c(Cl)c2)ccc1O
Show InChI InChI=1S/C17H12Cl2N2O4/c1-25-15-7-9(2-5-14(15)22)6-11-16(23)20-21(17(11)24)10-3-4-12(18)13(19)8-10/h2-8,22H,1H3,(H,20,23)
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n/an/a 2.50E+3n/an/an/an/an/an/a



Inje University

Curated by ChEMBL


Assay Description
Inhibition of Dyrk1 (unknown origin) autophosphorylation


Bioorg Med Chem Lett 19: 2324-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.062
BindingDB Entry DOI: 10.7270/Q2SN08VT
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Homo sapiens (Human))
BDBM50278597
PNG
(4-benzylidene-1-(3,4-dichlorophenyl)pyrazolidine-3...)
Show SMILES Clc1ccc(cc1Cl)N1NC(=O)C(=Cc2ccccc2)C1=O
Show InChI InChI=1S/C16H10Cl2N2O2/c17-13-7-6-11(9-14(13)18)20-16(22)12(15(21)19-20)8-10-4-2-1-3-5-10/h1-9H,(H,19,21)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Inje University

Curated by ChEMBL


Assay Description
Inhibition of Dyrk1 (unknown origin) autophosphorylation


Bioorg Med Chem Lett 19: 2324-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.062
BindingDB Entry DOI: 10.7270/Q2SN08VT
More data for this
Ligand-Target Pair
nucleotide-binding oligomerization domain containing 2


(Homo sapiens (Human))
BDBM59547
PNG
((4Z)-4-(3-bromo-4-hydroxy-5-methoxy-benzylidene)-1...)
Show SMILES COc1cc(\C=C2\C(=O)NN(C2=O)c2cccc(Cl)c2)cc(Br)c1O
Show InChI InChI=1S/C17H12BrClN2O4/c1-25-14-7-9(6-13(18)15(14)22)5-12-16(23)20-21(17(12)24)11-4-2-3-10(19)8-11/h2-8,22H,1H3,(H,20,23)/b12-5-
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n/an/a 2.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TH8K43
More data for this
Ligand-Target Pair
nucleotide-binding oligomerization domain containing 1


(Homo sapiens (Human))
BDBM59547
PNG
((4Z)-4-(3-bromo-4-hydroxy-5-methoxy-benzylidene)-1...)
Show SMILES COc1cc(\C=C2\C(=O)NN(C2=O)c2cccc(Cl)c2)cc(Br)c1O
Show InChI InChI=1S/C17H12BrClN2O4/c1-25-14-7-9(6-13(18)15(14)22)5-12-16(23)20-21(17(12)24)11-4-2-3-10(19)8-11/h2-8,22H,1H3,(H,20,23)/b12-5-
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n/an/a 3.49E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2Z899VD
More data for this
Ligand-Target Pair
nucleotide-binding oligomerization domain containing 1


(Homo sapiens (Human))
BDBM59547
PNG
((4Z)-4-(3-bromo-4-hydroxy-5-methoxy-benzylidene)-1...)
Show SMILES COc1cc(\C=C2\C(=O)NN(C2=O)c2cccc(Cl)c2)cc(Br)c1O
Show InChI InChI=1S/C17H12BrClN2O4/c1-25-14-7-9(6-13(18)15(14)22)5-12-16(23)20-21(17(12)24)11-4-2-3-10(19)8-11/h2-8,22H,1H3,(H,20,23)/b12-5-
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n/an/an/an/a 8.57E+3n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


Article DOI: 10.1016/j.bioorg.2013.09.002
BindingDB Entry DOI: 10.7270/Q2CN72C0
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Mus musculus)
BDBM50187069
PNG
(1-(3,4-dichlorophenyl)-4-(4-hydroxy-3-methoxybenzy...)
Show SMILES COc1cc(C=C2C(=O)NN(C2=O)c2ccc(Cl)c(Cl)c2)ccc1O
Show InChI InChI=1S/C17H12Cl2N2O4/c1-25-15-7-9(2-5-14(15)22)6-11-16(23)20-21(17(11)24)10-3-4-12(18)13(19)8-10/h2-8,22H,1H3,(H,20,23)
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n/an/a 2.50E+3n/an/an/an/an/an/a



Research Center IDRTech Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse Dyrk1A autophosphorylation in HEk293 cells


Bioorg Med Chem Lett 16: 3772-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.042
BindingDB Entry DOI: 10.7270/Q2K938BX
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM40431
PNG
((4Z)-4-[(3-methoxyphenyl)methylidene]-1-(4-methylp...)
Show SMILES COc1cccc(\C=C2\C(=O)NN(C2=O)c2ccc(C)cc2)c1
Show InChI InChI=1S/C18H16N2O3/c1-12-6-8-14(9-7-12)20-18(22)16(17(21)19-20)11-13-4-3-5-15(10-13)23-2/h3-11H,1-2H3,(H,19,21)/b16-11-
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n/an/a>6.67E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q22V2DH9
More data for this
Ligand-Target Pair