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1 similar compounds to monomer 50001672

Compile data set for download or QSAR
Wt: 385.4
BDBM50001649

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001649   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
LTB4R


(Homo sapiens (Human))
BDBM50001649
PNG
(2,4-Diphenyl-6-(5-tetrazol-1-yl-pentyloxy)-pyridin...)
Show SMILES C(CCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1)CCn1cnnn1
Show InChI InChI=1S/C23H23N5O/c1-4-10-19(11-5-1)21-16-22(20-12-6-2-7-13-20)25-23(17-21)29-15-9-3-8-14-28-18-24-26-27-28/h1-2,4-7,10-13,16-18H,3,8-9,14-15H2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 50n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.


J Med Chem 35: 4315-24 (1992)


Article DOI: 10.1021/jm00101a008
BindingDB Entry DOI: 10.7270/Q2QR4W2W
More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(Homo sapiens (Human))
BDBM50001649
PNG
(2,4-Diphenyl-6-(5-tetrazol-1-yl-pentyloxy)-pyridin...)
Show SMILES C(CCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1)CCn1cnnn1
Show InChI InChI=1S/C23H23N5O/c1-4-10-19(11-5-1)21-16-22(20-12-6-2-7-13-20)25-23(17-21)29-15-9-3-8-14-28-18-24-26-27-28/h1-2,4-7,10-13,16-18H,3,8-9,14-15H2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.


J Med Chem 35: 4315-24 (1992)


Article DOI: 10.1021/jm00101a008
BindingDB Entry DOI: 10.7270/Q2QR4W2W
More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(Homo sapiens (Human))
BDBM50001649
PNG
(2,4-Diphenyl-6-(5-tetrazol-1-yl-pentyloxy)-pyridin...)
Show SMILES C(CCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1)CCn1cnnn1
Show InChI InChI=1S/C23H23N5O/c1-4-10-19(11-5-1)21-16-22(20-12-6-2-7-13-20)25-23(17-21)29-15-9-3-8-14-28-18-24-26-27-28/h1-2,4-7,10-13,16-18H,3,8-9,14-15H2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes


J Med Chem 35: 4315-24 (1992)


Article DOI: 10.1021/jm00101a008
BindingDB Entry DOI: 10.7270/Q2QR4W2W
More data for this
Ligand-Target Pair