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1 similar compounds to monomer 50368583

Compile data set for download or QSAR
Wt: 396.4
BDBM50001961

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001961   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50001961
PNG
(CHEMBL195756)
Show SMILES CN1CCC23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccccc1)ccc5O
Show InChI InChI=1S/C26H24N2O2/c1-28-10-9-26-19-12-17-11-18(15-5-3-2-4-6-15)14-27-23(17)25(26)30-24-21(29)8-7-16(22(24)26)13-20(19)28/h2-8,11,14,19-20,25,29H,9-10,12-13H2,1H3/t19-,20?,25-,26?/m0/s1
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Article
PubMed
4.90n/an/an/an/an/an/an/an/a



University of Medicine& Dentistry of New Jersey-Robert Wood Johnson Medical School (UMDNJ-RWJMS)

Curated by ChEMBL


Assay Description
Binding affinity against Opioid receptor delta 1 from rat brain membranes using [3H]DADLE


J Med Chem 48: 1620-9 (2005)

Checked by Author
Article DOI: 10.1021/jm049117e
BindingDB Entry DOI: 10.7270/Q2ZP47MP
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001961
PNG
(CHEMBL195756)
Show SMILES CN1CCC23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccccc1)ccc5O
Show InChI InChI=1S/C26H24N2O2/c1-28-10-9-26-19-12-17-11-18(15-5-3-2-4-6-15)14-27-23(17)25(26)30-24-21(29)8-7-16(22(24)26)13-20(19)28/h2-8,11,14,19-20,25,29H,9-10,12-13H2,1H3/t19-,20?,25-,26?/m0/s1
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Article
PubMed
24n/an/an/an/an/an/an/an/a



University of Medicine& Dentistry of New Jersey-Robert Wood Johnson Medical School (UMDNJ-RWJMS)

Curated by ChEMBL


Assay Description
Binding affinity against Opioid receptor mu 1 from rat brain membranes using [3H]DAMGO


J Med Chem 48: 1620-9 (2005)

Checked by Author
Article DOI: 10.1021/jm049117e
BindingDB Entry DOI: 10.7270/Q2ZP47MP
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50001961
PNG
(CHEMBL195756)
Show SMILES CN1CCC23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccccc1)ccc5O
Show InChI InChI=1S/C26H24N2O2/c1-28-10-9-26-19-12-17-11-18(15-5-3-2-4-6-15)14-27-23(17)25(26)30-24-21(29)8-7-16(22(24)26)13-20(19)28/h2-8,11,14,19-20,25,29H,9-10,12-13H2,1H3/t19-,20?,25-,26?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
81n/an/an/an/an/an/an/an/a



University of Medicine& Dentistry of New Jersey-Robert Wood Johnson Medical School (UMDNJ-RWJMS)

Curated by ChEMBL


Assay Description
Binding affinity against Opioid receptor kappa 1 from guinea pig brain membranes using [3H]U-69593


J Med Chem 48: 1620-9 (2005)

Checked by Author
Article DOI: 10.1021/jm049117e
BindingDB Entry DOI: 10.7270/Q2ZP47MP
More data for this
Ligand-Target Pair