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1 similar compounds to monomer 50002151

Compile data set for download or QSAR
Wt: 217.2
BDBM50002153

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50002153   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
adrenergic Alpha2


(BOVINE)
BDBM50002153
PNG
(8-(4-Methyl-piperazin-1-yl)-imidazo[1,2-a]pyrazine...)
Show SMILES CN1CCN(CC1)c1nccn2ccnc12
Show InChI InChI=1S/C11H15N5/c1-14-6-8-16(9-7-14)11-10-12-2-4-15(10)5-3-13-11/h2-5H,6-9H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.02E+3n/an/an/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at Alpha-2 adrenergic receptor in calf cerebral cortex homogenates by [3H]clonidine displacement.


J Med Chem 35: 3845-57 (1992)


Article DOI: 10.1021/jm00099a012
BindingDB Entry DOI: 10.7270/Q2PZ59FX
More data for this
Ligand-Target Pair