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12 similar compounds to monomer 50010156

Compile data set for download or QSAR
Wt: 474.4
BDBM50003326
Wt: 490.4
BDBM50006330
Purchase
Wt: 502.5
BDBM50010158
Wt: 474.4
BDBM50010160
Wt: 474.4
BDBM50010163
Wt: 514.5
BDBM50010165
Wt: 446.4
BDBM50010169
Wt: 488.4
BDBM50010180
Wt: 488.4
BDBM50010186
Wt: 656.6
BDBM50054478
Wt: 656.6
BDBM50054479
Wt: 474.4
BDBM50421885

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50003326,50006330,50010158,50010160,50010163,50010165,50010169,50010180,50010186,50054478,50054479,50421885   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50003326
PNG
(3-[2-(2-Acetylamino-5-guanidino-pentanoylamino)-ac...)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(N)=O
Show InChI InChI=1S/C17H30N8O8/c1-8(27)23-9(3-2-4-21-17(19)20)15(32)22-6-12(28)24-10(5-13(29)30)16(33)25-11(7-26)14(18)31/h9-11,26H,2-7H2,1H3,(H2,18,31)(H,22,32)(H,23,27)(H,24,28)(H,25,33)(H,29,30)(H4,19,20,21)/t9-,10-,11-/m0/s1
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4.20E+3n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of 125[I] Fibrinogen binding to isolated purified human fibrinogen receptor


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50003326
PNG
(3-[2-(2-Acetylamino-5-guanidino-pentanoylamino)-ac...)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(N)=O
Show InChI InChI=1S/C17H30N8O8/c1-8(27)23-9(3-2-4-21-17(19)20)15(32)22-6-12(28)24-10(5-13(29)30)16(33)25-11(7-26)14(18)31/h9-11,26H,2-7H2,1H3,(H2,18,31)(H,22,32)(H,23,27)(H,24,28)(H,25,33)(H,29,30)(H4,19,20,21)/t9-,10-,11-/m0/s1
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3.70E+4n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma


J Med Chem 35: 3970-2 (1992)


Article DOI: 10.1021/jm00099a027
BindingDB Entry DOI: 10.7270/Q2V9871V
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50003326
PNG
(3-[2-(2-Acetylamino-5-guanidino-pentanoylamino)-ac...)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(N)=O
Show InChI InChI=1S/C17H30N8O8/c1-8(27)23-9(3-2-4-21-17(19)20)15(32)22-6-12(28)24-10(5-13(29)30)16(33)25-11(7-26)14(18)31/h9-11,26H,2-7H2,1H3,(H2,18,31)(H,22,32)(H,23,27)(H,24,28)(H,25,33)(H,29,30)(H4,19,20,21)/t9-,10-,11-/m0/s1
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6.20E+4n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50054478
PNG
(CHEMBL343123 | [(2S,5R,11S,14S)-11-Carboxymethyl-5...)
Show SMILES NC(=N)NCCC[C@H]1NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC1=O
Show InChI InChI=1S/C24H40N12O10/c25-23(26)29-5-1-3-11-19(43)31-9-15(37)34-14(8-18(41)42)22(46)36-12(4-2-6-30-24(27)28)20(44)32-10-16(38)33-13(7-17(39)40)21(45)35-11/h11-14H,1-10H2,(H,31,43)(H,32,44)(H,33,38)(H,34,37)(H,35,45)(H,36,46)(H,39,40)(H,41,42)(H4,25,26,29)(H4,27,28,30)/t11-,12+,13-,14-/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Texas A& M University

Curated by ChEMBL


Assay Description
Inhibition of human platelet aggregation mediated by alpha llb/beta3 interaction with fibrinogen


J Med Chem 39: 4520-6 (1996)


Article DOI: 10.1021/jm960276a
BindingDB Entry DOI: 10.7270/Q2X06885
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50006330
PNG
(3-{2-[2-(2-Amino-acetylamino)-5-guanidino-pentanoy...)
Show SMILES NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(O)=O
Show InChI InChI=1S/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1
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n/an/a 120n/an/an/an/an/an/a



Universite Catholique de Louvain

Curated by ChEMBL


Assay Description
Inhibition of human integrin alpha2b beta3 receptor by fibrinogen competitive binding assay


J Med Chem 52: 7029-43 (2009)


Article DOI: 10.1021/jm901133z
BindingDB Entry DOI: 10.7270/Q2GB2507
More data for this
Ligand-Target Pair
ITGAV/ITGB3


(Homo sapiens (Human))
BDBM50054478
PNG
(CHEMBL343123 | [(2S,5R,11S,14S)-11-Carboxymethyl-5...)
Show SMILES NC(=N)NCCC[C@H]1NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC1=O
Show InChI InChI=1S/C24H40N12O10/c25-23(26)29-5-1-3-11-19(43)31-9-15(37)34-14(8-18(41)42)22(46)36-12(4-2-6-30-24(27)28)20(44)32-10-16(38)33-13(7-17(39)40)21(45)35-11/h11-14H,1-10H2,(H,31,43)(H,32,44)(H,33,38)(H,34,37)(H,35,45)(H,36,46)(H,39,40)(H,41,42)(H4,25,26,29)(H4,27,28,30)/t11-,12+,13-,14-/m0/s1
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n/an/a 320n/an/an/an/an/an/a



Texas A& M University

Curated by ChEMBL


Assay Description
Inhibition of alphaV-beta3 interaction with vitronectin


J Med Chem 39: 4520-6 (1996)


Article DOI: 10.1021/jm960276a
BindingDB Entry DOI: 10.7270/Q2X06885
More data for this
Ligand-Target Pair
ITGAV/ITGB3


(Homo sapiens (Human))
BDBM50054479
PNG
(CHEMBL343122 | [(2S,5R,11R,14S)-11-Carboxymethyl-5...)
Show SMILES NC(=N)NCCC[C@H]1NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CC(O)=O)NC(=O)CNC1=O
Show InChI InChI=1S/C24H40N12O10/c25-23(26)29-5-1-3-11-19(43)31-9-15(37)34-14(8-18(41)42)22(46)36-12(4-2-6-30-24(27)28)20(44)32-10-16(38)33-13(7-17(39)40)21(45)35-11/h11-14H,1-10H2,(H,31,43)(H,32,44)(H,33,38)(H,34,37)(H,35,45)(H,36,46)(H,39,40)(H,41,42)(H4,25,26,29)(H4,27,28,30)/t11-,12+,13+,14-
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n/an/a 140n/an/an/an/an/an/a



Texas A& M University

Curated by ChEMBL


Assay Description
Inhibition of alphaV-beta3 interaction with vitronectin


J Med Chem 39: 4520-6 (1996)


Article DOI: 10.1021/jm960276a
BindingDB Entry DOI: 10.7270/Q2X06885
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50003326
PNG
(3-[2-(2-Acetylamino-5-guanidino-pentanoylamino)-ac...)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(N)=O
Show InChI InChI=1S/C17H30N8O8/c1-8(27)23-9(3-2-4-21-17(19)20)15(32)22-6-12(28)24-10(5-13(29)30)16(33)25-11(7-26)14(18)31/h9-11,26H,2-7H2,1H3,(H2,18,31)(H,22,32)(H,23,27)(H,24,28)(H,25,33)(H,29,30)(H4,19,20,21)/t9-,10-,11-/m0/s1
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n/an/a 9.13E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma


J Med Chem 35: 3970-2 (1992)


Article DOI: 10.1021/jm00099a027
BindingDB Entry DOI: 10.7270/Q2V9871V
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010158
PNG
(3-[4-amino(imino)methylamino-1-methylcarboxamido-(...)
Show SMILES CCNC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(C)=O
Show InChI InChI=1S/C19H34N8O8/c1-3-22-17(34)13(9-28)27-18(35)12(7-15(31)32)26-14(30)8-24-16(33)11(25-10(2)29)5-4-6-23-19(20)21/h11-13,28H,3-9H2,1-2H3,(H,22,34)(H,24,33)(H,25,29)(H,26,30)(H,27,35)(H,31,32)(H4,20,21,23)/t11-,12-,13-/m0/s1
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n/an/a>2.00E+5n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010186
PNG
(3-[4-amino(imino)methylamino-1-methylcarboxamido-(...)
Show SMILES CN(CC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(N)=O)C(=O)[C@H](CCCNC(N)=N)NC(C)=O
Show InChI InChI=1S/C18H32N8O8/c1-9(28)23-10(4-3-5-22-18(20)21)17(34)26(2)7-13(29)24-11(6-14(30)31)16(33)25-12(8-27)15(19)32/h10-12,27H,3-8H2,1-2H3,(H2,19,32)(H,23,28)(H,24,29)(H,25,33)(H,30,31)(H4,20,21,22)/t10-,11-,12-/m0/s1
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n/an/a>2.00E+5n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010165
PNG
(3-[1-[5-amino(imino)methylamino-2-methylcarboxamid...)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(N)=O
Show InChI InChI=1S/C20H34N8O8/c1-10(30)25-11(4-2-6-24-20(22)23)19(36)28-7-3-5-14(28)18(35)26-12(8-15(31)32)17(34)27-13(9-29)16(21)33/h11-14,29H,2-9H2,1H3,(H2,21,33)(H,25,30)(H,26,35)(H,27,34)(H,31,32)(H4,22,23,24)/t11-,12-,13-,14-/m0/s1
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n/an/a>2.00E+5n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010180
PNG
(3-[1-[4-amino(imino)methylamino-1-methylcarboxamid...)
Show SMILES C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(N)=O
Show InChI InChI=1S/C18H32N8O8/c1-8(23-16(33)10(24-9(2)28)4-3-5-22-18(20)21)15(32)25-11(6-13(29)30)17(34)26-12(7-27)14(19)31/h8,10-12,27H,3-7H2,1-2H3,(H2,19,31)(H,23,33)(H,24,28)(H,25,32)(H,26,34)(H,29,30)(H4,20,21,22)/t8-,10-,11-,12-/m0/s1
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n/an/a>2.00E+5n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010163
PNG
(3-[4-amino(imino)methylamino-1-methylcarboxamido-(...)
Show SMILES CC(=O)N[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(N)=O
Show InChI InChI=1S/C17H30N8O8/c1-8(27)23-9(3-2-4-21-17(19)20)15(32)22-6-12(28)24-10(5-13(29)30)16(33)25-11(7-26)14(18)31/h9-11,26H,2-7H2,1H3,(H2,18,31)(H,22,32)(H,23,27)(H,24,28)(H,25,33)(H,29,30)(H4,19,20,21)/t9-,10+,11+/m1/s1
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n/an/a>2.00E+5n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of 125[I] Fibrinogen binding to isolated purified human fibrinogen receptor


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010169
PNG
(3-[5-amino-1-methylcarboxamido-(1S)-pentylcarboxam...)
Show SMILES CC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(N)=O
Show InChI InChI=1S/C17H30N6O8/c1-9(25)21-10(4-2-3-5-18)16(30)20-7-13(26)22-11(6-14(27)28)17(31)23-12(8-24)15(19)29/h10-12,24H,2-8,18H2,1H3,(H2,19,29)(H,20,30)(H,21,25)(H,22,26)(H,23,31)(H,27,28)/t10-,11-,12-/m0/s1
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n/an/a>2.00E+5n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50421885
PNG
(CHEMBL2111672)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CO)C(N)=O
Show InChI InChI=1S/C17H30N8O8/c1-8(27)23-9(3-2-4-21-17(19)20)15(32)22-6-12(28)24-10(5-13(29)30)16(33)25-11(7-26)14(18)31/h9-11,26H,2-7H2,1H3,(H2,18,31)(H,22,32)(H,23,27)(H,24,28)(H,25,33)(H,29,30)(H4,19,20,21)/t9-,10+,11-/m0/s1
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n/an/a>2.00E+5n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50003326
PNG
(3-[2-(2-Acetylamino-5-guanidino-pentanoylamino)-ac...)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(N)=O
Show InChI InChI=1S/C17H30N8O8/c1-8(27)23-9(3-2-4-21-17(19)20)15(32)22-6-12(28)24-10(5-13(29)30)16(33)25-11(7-26)14(18)31/h9-11,26H,2-7H2,1H3,(H2,18,31)(H,22,32)(H,23,27)(H,24,28)(H,25,33)(H,29,30)(H4,19,20,21)/t9-,10-,11-/m0/s1
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n/an/a 6.72E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010160
PNG
(3-[4-amino(imino)methylamino-1-methylcarboxamido-(...)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CO)C(N)=O
Show InChI InChI=1S/C17H30N8O8/c1-8(27)23-9(3-2-4-21-17(19)20)15(32)22-6-12(28)24-10(5-13(29)30)16(33)25-11(7-26)14(18)31/h9-11,26H,2-7H2,1H3,(H2,18,31)(H,22,32)(H,23,27)(H,24,28)(H,25,33)(H,29,30)(H4,19,20,21)/t9-,10-,11+/m0/s1
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PubMed
n/an/a 1.38E+5n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50054479
PNG
(CHEMBL343122 | [(2S,5R,11R,14S)-11-Carboxymethyl-5...)
Show SMILES NC(=N)NCCC[C@H]1NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CC(O)=O)NC(=O)CNC1=O
Show InChI InChI=1S/C24H40N12O10/c25-23(26)29-5-1-3-11-19(43)31-9-15(37)34-14(8-18(41)42)22(46)36-12(4-2-6-30-24(27)28)20(44)32-10-16(38)33-13(7-17(39)40)21(45)35-11/h11-14H,1-10H2,(H,31,43)(H,32,44)(H,33,38)(H,34,37)(H,35,45)(H,36,46)(H,39,40)(H,41,42)(H4,25,26,29)(H4,27,28,30)/t11-,12+,13+,14-
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n/an/a>1.00E+5n/an/an/an/an/an/a



Texas A& M University

Curated by ChEMBL


Assay Description
Inhibition of human platelet aggregation mediated by alpha llb/beta3 interaction with fibrinogen


J Med Chem 39: 4520-6 (1996)


Article DOI: 10.1021/jm960276a
BindingDB Entry DOI: 10.7270/Q2X06885
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50003326
PNG
(3-[2-(2-Acetylamino-5-guanidino-pentanoylamino)-ac...)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(N)=O
Show InChI InChI=1S/C17H30N8O8/c1-8(27)23-9(3-2-4-21-17(19)20)15(32)22-6-12(28)24-10(5-13(29)30)16(33)25-11(7-26)14(18)31/h9-11,26H,2-7H2,1H3,(H2,18,31)(H,22,32)(H,23,27)(H,24,28)(H,25,33)(H,29,30)(H4,19,20,21)/t9-,10-,11-/m0/s1
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n/an/a 9.13E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50006330
PNG
(3-{2-[2-(2-Amino-acetylamino)-5-guanidino-pentanoy...)
Show SMILES NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(O)=O
Show InChI InChI=1S/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1
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n/an/a 1.60E+5n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma


J Med Chem 35: 2040-8 (1992)


Article DOI: 10.1021/jm00089a014
BindingDB Entry DOI: 10.7270/Q2S1833Q
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50006330
PNG
(3-{2-[2-(2-Amino-acetylamino)-5-guanidino-pentanoy...)
Show SMILES NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(O)=O
Show InChI InChI=1S/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1
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n/an/a 133n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
The compound was tested for the inhibition of fibrinogen receptor


J Med Chem 35: 2040-8 (1992)


Article DOI: 10.1021/jm00089a014
BindingDB Entry DOI: 10.7270/Q2S1833Q
More data for this
Ligand-Target Pair