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3 similar compounds to monomer 50004281

Compile data set for download or QSAR
Wt: 353.4
BDBM50004267
Wt: 325.4
BDBM50004270
Wt: 311.3
BDBM50004277

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50004267,50004270,50004277   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004267
PNG
(2-Oxo-1-propyl-1,2-dihydro-quinoline-4-carboxylic ...)
Show SMILES CCCn1c2ccccc2c(cc1=O)C(=O)NC1CC2CCC(C1)N2C
Show InChI InChI=1S/C21H27N3O2/c1-3-10-24-19-7-5-4-6-17(19)18(13-20(24)25)21(26)22-14-11-15-8-9-16(12-14)23(15)2/h4-7,13-16H,3,8-12H2,1-2H3,(H,22,26)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
67n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004277
PNG
(2-Oxo-1,2-dihydro-quinoline-4-carboxylic acid (8-m...)
Show SMILES CN1C2CCC1CC(C2)NC(=O)c1cc(=O)[nH]c2ccccc12
Show InChI InChI=1S/C18H21N3O2/c1-21-12-6-7-13(21)9-11(8-12)19-18(23)15-10-17(22)20-16-5-3-2-4-14(15)16/h2-5,10-13H,6-9H2,1H3,(H,19,23)(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>100n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004270
PNG
(1-Methyl-2-oxo-1,2-dihydro-quinoline-4-carboxylic ...)
Show SMILES CN1C2CCC1CC(C2)NC(=O)c1cc(=O)n(C)c2ccccc12
Show InChI InChI=1S/C19H23N3O2/c1-21-13-7-8-14(21)10-12(9-13)20-19(24)16-11-18(23)22(2)17-6-4-3-5-15(16)17/h3-6,11-14H,7-10H2,1-2H3,(H,20,24)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>100n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair