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3 similar compounds to monomer 50004289

Compile data set for download or QSAR
Wt: 367.4
BDBM50004285
Wt: 353.4
BDBM50004298
Wt: 327.4
BDBM50019521

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50004285,50004298,50019521   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004285
PNG
(2-Butoxy-quinoline-4-carboxylic acid (8-methyl-8-a...)
Show SMILES CCCCOc1cc(C(=O)NC2CC3CCC(C2)N3C)c2ccccc2n1
Show InChI InChI=1S/C22H29N3O2/c1-3-4-11-27-21-14-19(18-7-5-6-8-20(18)24-21)22(26)23-15-12-16-9-10-17(13-15)25(16)2/h5-8,14-17H,3-4,9-13H2,1-2H3,(H,23,26)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
19n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004298
PNG
(2-Isopropoxy-quinoline-4-carboxylic acid (8-methyl...)
Show SMILES CC(C)Oc1cc(C(=O)NC2CC3CCC(C2)N3C)c2ccccc2n1
Show InChI InChI=1S/C21H27N3O2/c1-13(2)26-20-12-18(17-6-4-5-7-19(17)23-20)21(25)22-14-10-15-8-9-16(11-14)24(15)3/h4-7,12-16H,8-11H2,1-3H3,(H,22,25)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
53n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair
HTR4


(GUINEA PIG)
BDBM50019521
PNG
(CHEMBL3291076)
Show SMILES COc1cc(C(=O)NCCCN2CCCCC2)c2ccccc2n1
Show InChI InChI=1S/C19H25N3O2/c1-24-18-14-16(15-8-3-4-9-17(15)21-18)19(23)20-10-7-13-22-11-5-2-6-12-22/h3-4,8-9,14H,2,5-7,10-13H2,1H3,(H,20,23)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 mins


Eur J Med Chem 82: 36-46 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.015
BindingDB Entry DOI: 10.7270/Q21Z45ZQ
More data for this
Ligand-Target Pair