BindingDB logo
myBDB logout

49 similar compounds to monomer 50008029

Compile data set for download or QSAR
Wt: 507.4
BDBM50006269
Wt: 392.4
BDBM50009857
Wt: 414.4
BDBM50009862
Wt: 392.4
BDBM50009863
Wt: 398.4
BDBM50009864
Wt: 434.5
BDBM50009865
Wt: 323.3
BDBM50009866
Wt: 420.5
BDBM50009867
Wt: 364.4
BDBM50009868
Wt: 377.4
BDBM50009869
Wt: 366.4
BDBM50009870
Wt: 408.4
BDBM50032541
Wt: 412.5
BDBM50032544
Wt: 412.5
BDBM50032545
Wt: 396.4
BDBM50032546
Displayed 1 to 15 (of 49 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50006269,50009857,50009862,50009863,50009864,50009865,50009866,50009867,50009868,50009869,50009870,50032541,50032544,50032545,50032546   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50006269
PNG
(CHEMBL3234669)
Show SMILES COc1cccc2c(C(=O)c3ccc(Br)c4ccccc34)c(C)n(CCN3CCOCC3)c12
Show InChI InChI=1S/C27H27BrN2O3/c1-18-25(27(31)21-10-11-23(28)20-7-4-3-6-19(20)21)22-8-5-9-24(32-2)26(22)30(18)13-12-29-14-16-33-17-15-29/h3-11H,12-17H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.80n/an/an/an/an/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to CB2 receptor (unknown origin)


Cell Chem Biol 56: 8224-56 (2013)


Article DOI: 10.1021/jm4005626
BindingDB Entry DOI: 10.7270/Q2B859M5
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50009864
PNG
(CHEMBL274833 | [2-Methyl-1-(2-morpholin-4-yl-ethyl...)
Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2ccccc2n1CCN1CCOCC1
Show InChI InChI=1S/C26H26N2O2/c1-19-25(26(29)22-11-6-8-20-7-2-3-9-21(20)22)23-10-4-5-12-24(23)28(19)14-13-27-15-17-30-18-16-27/h2-12H,13-18H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
14n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Evaluated for binding affinity against recombinant human peripheral cannabinoid receptor 2


Bioorg Med Chem Lett 6: 2263-2268 (1996)


Article DOI: 10.1016/0960-894X(96)00426-X
BindingDB Entry DOI: 10.7270/Q2MS3SRN
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50009864
PNG
(CHEMBL274833 | [2-Methyl-1-(2-morpholin-4-yl-ethyl...)
Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2ccccc2n1CCN1CCOCC1
Show InChI InChI=1S/C26H26N2O2/c1-19-25(26(29)22-11-6-8-20-7-2-3-9-21(20)22)23-10-4-5-12-24(23)28(19)14-13-27-15-17-30-18-16-27/h2-12H,13-18H2,1H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
638n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Evaluated for binding affinity against recombinant human central cannabinoid receptor 1


Bioorg Med Chem Lett 6: 2263-2268 (1996)


Article DOI: 10.1016/0960-894X(96)00426-X
BindingDB Entry DOI: 10.7270/Q2MS3SRN
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50006269
PNG
(CHEMBL3234669)
Show SMILES COc1cccc2c(C(=O)c3ccc(Br)c4ccccc34)c(C)n(CCN3CCOCC3)c12
Show InChI InChI=1S/C27H27BrN2O3/c1-18-25(27(31)21-10-11-23(28)20-7-4-3-6-19(20)21)22-8-5-9-24(32-2)26(22)30(18)13-12-29-14-16-33-17-15-29/h3-11H,12-17H2,1-2H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to CB1 receptor (unknown origin)


Cell Chem Biol 56: 8224-56 (2013)


Article DOI: 10.1021/jm4005626
BindingDB Entry DOI: 10.7270/Q2B859M5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50009868
PNG
((4-Methoxy-phenyl)-[1-(2-morpholin-4-yl-ethyl)-1H-...)
Show SMILES COc1ccc(cc1)C(=O)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C22H24N2O3/c1-26-18-8-6-17(7-9-18)22(25)20-16-24(21-5-3-2-4-19(20)21)11-10-23-12-14-27-15-13-23/h2-9,16H,10-15H2,1H3
PDB

Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 390n/an/an/an/an/an/a



Sanofi Research Division

Curated by ChEMBL


Assay Description
Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.


J Med Chem 38: 3094-105 (1995)


Article DOI: 10.1021/jm00016a013
BindingDB Entry DOI: 10.7270/Q2DN442Z
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50032544
PNG
(CHEMBL79204 | {2-Methyl-1-[2-(2-methyl-morpholin-4...)
Show SMILES CC1CN(CCn2c(C)c(C(=O)c3cccc4ccccc34)c3ccccc23)CCO1
Show InChI InChI=1/C27H28N2O2/c1-19-18-28(16-17-31-19)14-15-29-20(2)26(24-11-5-6-13-25(24)29)27(30)23-12-7-9-21-8-3-4-10-22(21)23/h3-13,19H,14-18H2,1-2H3
PDB

Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 59n/an/an/an/an/an/a



Sanofi Research Division

Curated by ChEMBL


Assay Description
Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.


J Med Chem 38: 3094-105 (1995)


Article DOI: 10.1021/jm00016a013
BindingDB Entry DOI: 10.7270/Q2DN442Z
More data for this
Ligand-Target Pair
Adenylate cyclase type V


(Rattus norvegicus)
BDBM50009864
PNG
(CHEMBL274833 | [2-Methyl-1-(2-morpholin-4-yl-ethyl...)
Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2ccccc2n1CCN1CCOCC1
Show InChI InChI=1S/C26H26N2O2/c1-19-25(26(29)22-11-6-8-20-7-2-3-9-21(20)22)23-10-4-5-12-24(23)28(19)14-13-27-15-17-30-18-16-27/h2-12H,13-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 370n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Compound was evaluated for inhibition of hormone stimulated Adenylate cyclase activity in N18TG2 membranes.


J Med Chem 39: 1967-74 (1996)


Article DOI: 10.1021/jm950932r
BindingDB Entry DOI: 10.7270/Q27M071B
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50009864
PNG
(CHEMBL274833 | [2-Methyl-1-(2-morpholin-4-yl-ethyl...)
Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2ccccc2n1CCN1CCOCC1
Show InChI InChI=1S/C26H26N2O2/c1-19-25(26(29)22-11-6-8-20-7-2-3-9-21(20)22)23-10-4-5-12-24(23)28(19)14-13-27-15-17-30-18-16-27/h2-12H,13-18H2,1H3
PDB

Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 73n/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against brain Cannabinoid receptor 1 using [3H]-CP-55,940 as radioligand at 1.1 nM concentration


J Med Chem 39: 1967-74 (1996)


Article DOI: 10.1021/jm950932r
BindingDB Entry DOI: 10.7270/Q27M071B
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009857
PNG
((4-Methoxy-phenyl)-[2-methyl-1-(1-methyl-2-morphol...)
Show SMILES COc1ccc(cc1)C(=O)c1c(C)n(C(C)CN2CCOCC2)c2ccccc12
Show InChI InChI=1/C24H28N2O3/c1-17(16-25-12-14-29-15-13-25)26-18(2)23(21-6-4-5-7-22(21)26)24(27)19-8-10-20(28-3)11-9-19/h4-11,17H,12-16H2,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 900n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009862
PNG
(CHEMBL12566 | {1-[2-(2-Hydroxy-morpholin-4-yl)-eth...)
Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2ccccc2n1CCN1CCOC(O)C1
Show InChI InChI=1/C26H26N2O3/c1-18-25(26(30)21-11-6-8-19-7-2-3-9-20(19)21)22-10-4-5-12-23(22)28(18)14-13-27-15-16-31-24(29)17-27/h2-12,24,29H,13-17H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 570n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in mouse vas deferens


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009863
PNG
(CHEMBL273372 | [2-Ethyl-1-(2-morpholin-4-yl-ethyl)...)
Show SMILES CCc1c(C(=O)c2ccc(OC)cc2)c2ccccc2n1CCN1CCOCC1
Show InChI InChI=1S/C24H28N2O3/c1-3-21-23(24(27)18-8-10-19(28-2)11-9-18)20-6-4-5-7-22(20)26(21)13-12-25-14-16-29-17-15-25/h4-11H,3,12-17H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009865
PNG
((4-Methoxy-phenyl)-[2-methyl-1-(6-morpholin-4-yl-h...)
Show SMILES COc1ccc(cc1)C(=O)c1c(C)n(CCCCCCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C27H34N2O3/c1-21-26(27(30)22-11-13-23(31-2)14-12-22)24-9-5-6-10-25(24)29(21)16-8-4-3-7-15-28-17-19-32-20-18-28/h5-6,9-14H,3-4,7-8,15-20H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009866
PNG
(CHEMBL275312 | [3-(4-Methoxy-benzoyl)-2-methyl-ind...)
Show SMILES COc1ccc(cc1)C(=O)c1c(C)n(CC(O)=O)c2ccccc12
Show InChI InChI=1S/C19H17NO4/c1-12-18(19(23)13-7-9-14(24-2)10-8-13)15-5-3-4-6-16(15)20(12)11-17(21)22/h3-10H,11H2,1-2H3,(H,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009864
PNG
(CHEMBL274833 | [2-Methyl-1-(2-morpholin-4-yl-ethyl...)
Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2ccccc2n1CCN1CCOCC1
Show InChI InChI=1S/C26H26N2O2/c1-19-25(26(29)22-11-6-8-20-7-2-3-9-21(20)22)23-10-4-5-12-24(23)28(19)14-13-27-15-17-30-18-16-27/h2-12H,13-18H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009867
PNG
((4-Methoxy-phenyl)-[2-methyl-1-(5-morpholin-4-yl-p...)
Show SMILES COc1ccc(cc1)C(=O)c1c(C)n(CCCCCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C26H32N2O3/c1-20-25(26(29)21-10-12-22(30-2)13-11-21)23-8-4-5-9-24(23)28(20)15-7-3-6-14-27-16-18-31-19-17-27/h4-5,8-13H,3,6-7,14-19H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009868
PNG
((4-Methoxy-phenyl)-[1-(2-morpholin-4-yl-ethyl)-1H-...)
Show SMILES COc1ccc(cc1)C(=O)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C22H24N2O3/c1-26-18-8-6-17(7-9-18)22(25)20-16-24(21-5-3-2-4-19(20)21)11-10-23-12-14-27-15-13-23/h2-9,16H,10-15H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in mouse vas deferens


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009869
PNG
((4-Methoxy-phenyl)-[2-methyl-1-(2-piperazin-1-yl-e...)
Show SMILES COc1ccc(cc1)C(=O)c1c(C)n(CCN2CCNCC2)c2ccccc12
Show InChI InChI=1S/C23H27N3O2/c1-17-22(23(27)18-7-9-19(28-2)10-8-18)20-5-3-4-6-21(20)26(17)16-15-25-13-11-24-12-14-25/h3-10,24H,11-16H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009870
PNG
((2-Fluoro-phenyl)-[2-methyl-1-(2-morpholin-4-yl-et...)
Show SMILES Cc1c(C(=O)c2ccccc2F)c2ccccc2n1CCN1CCOCC1
Show InChI InChI=1S/C22H23FN2O2/c1-16-21(22(26)17-6-2-4-8-19(17)23)18-7-3-5-9-20(18)25(16)11-10-24-12-14-27-15-13-24/h2-9H,10-15H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50009864
PNG
(CHEMBL274833 | [2-Methyl-1-(2-morpholin-4-yl-ethyl...)
Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2ccccc2n1CCN1CCOCC1
Show InChI InChI=1S/C26H26N2O2/c1-19-25(26(29)22-11-6-8-20-7-2-3-9-21(20)22)23-10-4-5-12-24(23)28(19)14-13-27-15-17-30-18-16-27/h2-12H,13-18H2,1H3
PDB

Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 19n/an/an/an/an/an/a



Sanofi Research Division

Curated by ChEMBL


Assay Description
Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.


J Med Chem 38: 3094-105 (1995)


Article DOI: 10.1021/jm00016a013
BindingDB Entry DOI: 10.7270/Q2DN442Z
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50032545
PNG
(CHEMBL80984 | {2-Methyl-1-[2-(3-methyl-morpholin-4...)
Show SMILES CC1COCCN1CCn1c(C)c(C(=O)c2cccc3ccccc23)c2ccccc12
Show InChI InChI=1/C27H28N2O2/c1-19-18-31-17-16-28(19)14-15-29-20(2)26(24-11-5-6-13-25(24)29)27(30)23-12-7-9-21-8-3-4-10-22(21)23/h3-13,19H,14-18H2,1-2H3
PDB

Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 384n/an/an/an/an/an/a



Sanofi Research Division

Curated by ChEMBL


Assay Description
Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.


J Med Chem 38: 3094-105 (1995)


Article DOI: 10.1021/jm00016a013
BindingDB Entry DOI: 10.7270/Q2DN442Z
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009868
PNG
((4-Methoxy-phenyl)-[1-(2-morpholin-4-yl-ethyl)-1H-...)
Show SMILES COc1ccc(cc1)C(=O)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C22H24N2O3/c1-26-18-8-6-17(7-9-18)22(25)20-16-24(21-5-3-2-4-19(20)21)11-10-23-12-14-27-15-13-23/h2-9,16H,10-15H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50032541
PNG
(CHEMBL310751 | [6-Methoxy-2-methyl-1-(2-morpholin-...)
Show SMILES COc1ccc(cc1)C(=O)c1c(C)n(CCN2CCOCC2)c2cc(OC)ccc12
Show InChI InChI=1S/C24H28N2O4/c1-17-23(24(27)18-4-6-19(28-2)7-5-18)21-9-8-20(29-3)16-22(21)26(17)11-10-25-12-14-30-15-13-25/h4-9,16H,10-15H2,1-3H3
PDB

Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.45E+3n/an/an/an/an/an/a



Sanofi Research Division

Curated by ChEMBL


Assay Description
Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.


J Med Chem 38: 3094-105 (1995)


Article DOI: 10.1021/jm00016a013
BindingDB Entry DOI: 10.7270/Q2DN442Z
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50032546
PNG
(CHEMBL78701 | [7-Fluoro-2-methyl-1-(2-morpholin-4-...)
Show SMILES COc1ccc(cc1)C(=O)c1c(C)n(CCN2CCOCC2)c2c(F)cccc12
Show InChI InChI=1S/C23H25FN2O3/c1-16-21(23(27)17-6-8-18(28-2)9-7-17)19-4-3-5-20(24)22(19)26(16)11-10-25-12-14-29-15-13-25/h3-9H,10-15H2,1-2H3
PDB

Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 571n/an/an/an/an/an/a



Sanofi Research Division

Curated by ChEMBL


Assay Description
Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.


J Med Chem 38: 3094-105 (1995)


Article DOI: 10.1021/jm00016a013
BindingDB Entry DOI: 10.7270/Q2DN442Z
More data for this
Ligand-Target Pair