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1 similar compounds to monomer 50009777

Compile data set for download or QSAR
Wt: 441.2
BDBM50006478

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006478   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase (AR)


(Homo sapiens (Human))
BDBM50006478
PNG
(CHEMBL67922 | [3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3...)
Show SMILES OC(=O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c2cc3ccccc3cc12
Show InChI InChI=1S/C21H14BrFN2O3/c22-15-6-5-14(18(23)9-15)11-25-21(28)17-8-13-4-2-1-3-12(13)7-16(17)19(24-25)10-20(26)27/h1-9H,10-11H2,(H,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase isolated from human placenta


J Med Chem 35: 2155-62 (1992)


Article DOI: 10.1021/jm00090a002
BindingDB Entry DOI: 10.7270/Q2KK99RR
More data for this
Ligand-Target Pair