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11 similar compounds to monomer 50045797

Compile data set for download or QSAR
Wt: 476.6
BDBM50008637
Wt: 497.0
BDBM50008672
Wt: 476.6
BDBM50008645
Wt: 476.6
BDBM50008650
Wt: 476.6
BDBM50008651
Wt: 497.0
BDBM50008654
Wt: 490.5
BDBM50045820
Wt: 578.5
BDBM50071734
Wt: 544.0
BDBM50071740
Wt: 807.3
BDBM50152247
Wt: 524.6
BDBM50288242

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50008637,50008672,50008645,50008650,50008651,50008654,50045820,50071734,50071740,50152247,50288242   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NMBR


(Homo sapiens (Human))
BDBM50071734
PNG
((S)-2-[3-(3,4-Dichloro-phenyl)-ureido]-3-(1H-indol...)
Show SMILES C[C@@](Cc1c[nH]c2ccccc12)(NC(=O)Nc1ccc(Cl)c(Cl)c1)C(=O)NCC1(CCCCC1)c1ccccn1
Show InChI InChI=1S/C31H33Cl2N5O2/c1-30(18-21-19-35-26-10-4-3-9-23(21)26,38-29(40)37-22-12-13-24(32)25(33)17-22)28(39)36-20-31(14-6-2-7-15-31)27-11-5-8-16-34-27/h3-5,8-13,16-17,19,35H,2,6-7,14-15,18,20H2,1H3,(H,36,39)(H2,37,38,40)/t30-/m0/s1
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2.10n/an/an/an/an/an/an/an/a



Cambridge University Forvie Site

Curated by ChEMBL


Assay Description
Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells


Bioorg Med Chem Lett 8: 2589-94 (1999)


Article DOI: 10.1016/s0960-894x(98)00462-4
BindingDB Entry DOI: 10.7270/Q2DB82B4
More data for this
Ligand-Target Pair
NMBR


(Homo sapiens (Human))
BDBM50071740
PNG
((S)-2-[3-(4-Chloro-phenyl)-ureido]-3-(1H-indol-3-y...)
Show SMILES C[C@@](Cc1c[nH]c2ccccc12)(NC(=O)Nc1ccc(Cl)cc1)C(=O)NCC1(CCCCC1)c1ccccn1
Show InChI InChI=1S/C31H34ClN5O2/c1-30(19-22-20-34-26-10-4-3-9-25(22)26,37-29(39)36-24-14-12-23(32)13-15-24)28(38)35-21-31(16-6-2-7-17-31)27-11-5-8-18-33-27/h3-5,8-15,18,20,34H,2,6-7,16-17,19,21H2,1H3,(H,35,38)(H2,36,37,39)/t30-/m0/s1
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2.80n/an/an/an/an/an/an/an/a



Cambridge University Forvie Site

Curated by ChEMBL


Assay Description
Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells


Bioorg Med Chem Lett 8: 2589-94 (1999)


Article DOI: 10.1016/s0960-894x(98)00462-4
BindingDB Entry DOI: 10.7270/Q2DB82B4
More data for this
Ligand-Target Pair
GRPR


(Homo sapiens (Human))
BDBM50071734
PNG
((S)-2-[3-(3,4-Dichloro-phenyl)-ureido]-3-(1H-indol...)
Show SMILES C[C@@](Cc1c[nH]c2ccccc12)(NC(=O)Nc1ccc(Cl)c(Cl)c1)C(=O)NCC1(CCCCC1)c1ccccn1
Show InChI InChI=1S/C31H33Cl2N5O2/c1-30(18-21-19-35-26-10-4-3-9-23(21)26,38-29(40)37-22-12-13-24(32)25(33)17-22)28(39)36-20-31(14-6-2-7-15-31)27-11-5-8-16-34-27/h3-5,8-13,16-17,19,35H,2,6-7,14-15,18,20H2,1H3,(H,36,39)(H2,37,38,40)/t30-/m0/s1
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85n/an/an/an/an/an/an/an/a



Cambridge University Forvie Site

Curated by ChEMBL


Assay Description
In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.


Bioorg Med Chem Lett 8: 2589-94 (1999)


Article DOI: 10.1016/s0960-894x(98)00462-4
BindingDB Entry DOI: 10.7270/Q2DB82B4
More data for this
Ligand-Target Pair
GRPR


(Homo sapiens (Human))
BDBM50071740
PNG
((S)-2-[3-(4-Chloro-phenyl)-ureido]-3-(1H-indol-3-y...)
Show SMILES C[C@@](Cc1c[nH]c2ccccc12)(NC(=O)Nc1ccc(Cl)cc1)C(=O)NCC1(CCCCC1)c1ccccn1
Show InChI InChI=1S/C31H34ClN5O2/c1-30(19-22-20-34-26-10-4-3-9-25(22)26,37-29(39)36-24-14-12-23(32)13-15-24)28(38)35-21-31(16-6-2-7-17-31)27-11-5-8-18-33-27/h3-5,8-15,18,20,34H,2,6-7,16-17,19,21H2,1H3,(H,35,38)(H2,36,37,39)/t30-/m0/s1
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149n/an/an/an/an/an/an/an/a



Cambridge University Forvie Site

Curated by ChEMBL


Assay Description
In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.


Bioorg Med Chem Lett 8: 2589-94 (1999)


Article DOI: 10.1016/s0960-894x(98)00462-4
BindingDB Entry DOI: 10.7270/Q2DB82B4
More data for this
Ligand-Target Pair
NMBR


(Homo sapiens (Human))
BDBM50288242
PNG
(2-[3-(2,6-Diisopropyl-phenyl)-ureido]-3-(1H-indol-...)
Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NC(C)(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1
Show InChI InChI=1S/C33H40N4O2/c1-22(2)26-15-11-16-27(23(3)4)30(26)36-32(39)37-33(5,20-25-21-35-29-17-10-9-14-28(25)29)31(38)34-19-18-24-12-7-6-8-13-24/h6-17,21-23,35H,18-20H2,1-5H3,(H,34,38)(H2,36,37,39)
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450n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against [125 I][4Tyr]-bombesin labeled cloned human NMB receptor stably expressed in CHO cells


Bioorg Med Chem Lett 6: 2617-2622 (1996)


Article DOI: 10.1016/0960-894X(96)00481-7
BindingDB Entry DOI: 10.7270/Q2NC61QD
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50045820
PNG
(3-(1H-Indol-3-yl)-2-methyl-2-(3-naphthalen-2-yl-ur...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)Nc1ccc2ccccc2c1)C(=O)NCCc1ccccc1
Show InChI InChI=1S/C31H30N4O2/c1-31(20-25-21-33-28-14-8-7-13-27(25)28,29(36)32-18-17-22-9-3-2-4-10-22)35-30(37)34-26-16-15-23-11-5-6-12-24(23)19-26/h2-16,19,21,33H,17-18,20H2,1H3,(H,32,36)(H2,34,35,37)
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769n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Tested for inhibition of [3H]-pCCK-8 specific binding to cholecystokinin type A receptor in guinea pig pancreatic membranes


J Med Chem 36: 2868-77 (1993)


Article DOI: 10.1021/jm00072a005
BindingDB Entry DOI: 10.7270/Q2MG7NK5
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50045820
PNG
(3-(1H-Indol-3-yl)-2-methyl-2-(3-naphthalen-2-yl-ur...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)Nc1ccc2ccccc2c1)C(=O)NCCc1ccccc1
Show InChI InChI=1S/C31H30N4O2/c1-31(20-25-21-33-28-14-8-7-13-27(25)28,29(36)32-18-17-22-9-3-2-4-10-22)35-30(37)34-26-16-15-23-11-5-6-12-24(23)19-26/h2-16,19,21,33H,17-18,20H2,1H3,(H,32,36)(H2,34,35,37)
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3.48E+3n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Tested for inhibition of [3H]-pCCK-8 specific binding to cholecystokinin type B receptor in guinea pig brain cortex


J Med Chem 36: 2868-77 (1993)


Article DOI: 10.1021/jm00072a005
BindingDB Entry DOI: 10.7270/Q2MG7NK5
More data for this
Ligand-Target Pair
GRPR


(Homo sapiens (Human))
BDBM50288242
PNG
(2-[3-(2,6-Diisopropyl-phenyl)-ureido]-3-(1H-indol-...)
Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NC(C)(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1
Show InChI InChI=1S/C33H40N4O2/c1-22(2)26-15-11-16-27(23(3)4)30(26)36-32(39)37-33(5,20-25-21-35-29-17-10-9-14-28(25)29)31(38)34-19-18-24-12-7-6-8-13-24/h6-17,21-23,35H,18-20H2,1-5H3,(H,34,38)(H2,36,37,39)
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>1.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against [125 I][4Tyr]-bombesin labeled cloned human GRP(gastrin releasing peptide) receptors stably expressed in CHO cells


Bioorg Med Chem Lett 6: 2617-2622 (1996)


Article DOI: 10.1016/0960-894X(96)00481-7
BindingDB Entry DOI: 10.7270/Q2NC61QD
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50008672
PNG
((S)-2-[3-(4-Chloro-phenyl)-ureido]-3-(1H-indol-3-y...)
Show SMILES CCCCCN(CCCCC)C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C28H37ClN4O2/c1-3-5-9-17-33(18-10-6-4-2)27(34)26(19-21-20-30-25-12-8-7-11-24(21)25)32-28(35)31-23-15-13-22(29)14-16-23/h7-8,11-16,20,26,30H,3-6,9-10,17-19H2,1-2H3,(H2,31,32,35)/t26-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Bolton-Hunter CCK-8 binding to cholecystokinin type B receptor in guinea pig cerebral cortical.


J Med Chem 34: 3350-9 (1992)


Article DOI: 10.1021/jm00116a002
BindingDB Entry DOI: 10.7270/Q2M907M8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50008650
PNG
((S)-3-(1H-Indol-3-yl)-N,N-dipentyl-2-(3-m-tolyl-ur...)
Show SMILES CCCCCN(CCCCC)C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C29H40N4O2/c1-4-6-10-17-33(18-11-7-5-2)28(34)27(20-23-21-30-26-16-9-8-15-25(23)26)32-29(35)31-24-14-12-13-22(3)19-24/h8-9,12-16,19,21,27,30H,4-7,10-11,17-18,20H2,1-3H3,(H2,31,32,35)/t27-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Bolton-Hunter CCK-8 binding to cholecystokinin type B receptor in guinea pig cerebral cortical.


J Med Chem 34: 3350-9 (1992)


Article DOI: 10.1021/jm00116a002
BindingDB Entry DOI: 10.7270/Q2M907M8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50008645
PNG
((S)-3-(1H-Indol-3-yl)-N,N-dipentyl-2-(3-p-tolyl-ur...)
Show SMILES CCCCCN(CCCCC)C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Nc1ccc(C)cc1
Show InChI InChI=1S/C29H40N4O2/c1-4-6-10-18-33(19-11-7-5-2)28(34)27(20-23-21-30-26-13-9-8-12-25(23)26)32-29(35)31-24-16-14-22(3)15-17-24/h8-9,12-17,21,27,30H,4-7,10-11,18-20H2,1-3H3,(H2,31,32,35)/t27-/m0/s1
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n/an/a 9.25E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Bolton-Hunter CCK-8 binding to cholecystokinin type B receptor in guinea pig cerebral cortical.


J Med Chem 34: 3350-9 (1992)


Article DOI: 10.1021/jm00116a002
BindingDB Entry DOI: 10.7270/Q2M907M8
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50152247
PNG
(2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-1-oxo-2-(3-pheny...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)Nc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C42H47ClN10O5/c43-29-19-17-27(18-20-29)23-36(53-42(58)49-30-12-5-2-6-13-30)40(57)52-35(22-26-10-3-1-4-11-26)39(56)50-33(16-9-21-47-41(45)46)38(55)51-34(37(44)54)24-28-25-48-32-15-8-7-14-31(28)32/h1-8,10-15,17-20,25,33-36,48H,9,16,21-24H2,(H2,44,54)(H,50,56)(H,51,55)(H,52,57)(H4,45,46,47)(H2,49,53,58)/t33-,34-,35-,36-/m0/s1
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n/an/an/an/a 93n/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Agonistic activity against against human Melanocortin 3 receptor


Bioorg Med Chem Lett 14: 4839-42 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.046
BindingDB Entry DOI: 10.7270/Q2445KX8
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50152247
PNG
(2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-1-oxo-2-(3-pheny...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)Nc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C42H47ClN10O5/c43-29-19-17-27(18-20-29)23-36(53-42(58)49-30-12-5-2-6-13-30)40(57)52-35(22-26-10-3-1-4-11-26)39(56)50-33(16-9-21-47-41(45)46)38(55)51-34(37(44)54)24-28-25-48-32-15-8-7-14-31(28)32/h1-8,10-15,17-20,25,33-36,48H,9,16,21-24H2,(H2,44,54)(H,50,56)(H,51,55)(H,52,57)(H4,45,46,47)(H2,49,53,58)/t33-,34-,35-,36-/m0/s1
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n/an/an/an/a 985n/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Agonistic activity against against human Melanocortin 1 receptor


Bioorg Med Chem Lett 14: 4839-42 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.046
BindingDB Entry DOI: 10.7270/Q2445KX8
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50152247
PNG
(2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-1-oxo-2-(3-pheny...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)Nc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C42H47ClN10O5/c43-29-19-17-27(18-20-29)23-36(53-42(58)49-30-12-5-2-6-13-30)40(57)52-35(22-26-10-3-1-4-11-26)39(56)50-33(16-9-21-47-41(45)46)38(55)51-34(37(44)54)24-28-25-48-32-15-8-7-14-31(28)32/h1-8,10-15,17-20,25,33-36,48H,9,16,21-24H2,(H2,44,54)(H,50,56)(H,51,55)(H,52,57)(H4,45,46,47)(H2,49,53,58)/t33-,34-,35-,36-/m0/s1
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n/an/an/an/a 146n/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Agonistic activity against against human Melanocortin 4 receptor


Bioorg Med Chem Lett 14: 4839-42 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.046
BindingDB Entry DOI: 10.7270/Q2445KX8
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50008637
PNG
((R)-3-(1H-Indol-3-yl)-N,N-dipentyl-2-(3-p-tolyl-ur...)
Show SMILES CCCCCN(CCCCC)C(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)Nc1ccc(C)cc1
Show InChI InChI=1S/C29H40N4O2/c1-4-6-10-18-33(19-11-7-5-2)28(34)27(20-23-21-30-26-13-9-8-12-25(23)26)32-29(35)31-24-16-14-22(3)15-17-24/h8-9,12-17,21,27,30H,4-7,10-11,18-20H2,1-3H3,(H2,31,32,35)/t27-/m1/s1
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n/an/a 2.50E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreatic membranes.


J Med Chem 34: 3350-9 (1992)


Article DOI: 10.1021/jm00116a002
BindingDB Entry DOI: 10.7270/Q2M907M8
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50008651
PNG
((R)-3-(1H-Indol-3-yl)-N,N-dipentyl-2-(3-m-tolyl-ur...)
Show SMILES CCCCCN(CCCCC)C(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C29H40N4O2/c1-4-6-10-17-33(18-11-7-5-2)28(34)27(20-23-21-30-26-16-9-8-15-25(23)26)32-29(35)31-24-14-12-13-22(3)19-24/h8-9,12-16,19,21,27,30H,4-7,10-11,17-18,20H2,1-3H3,(H2,31,32,35)/t27-/m1/s1
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n/an/a 1.10E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreatic membranes.


J Med Chem 34: 3350-9 (1992)


Article DOI: 10.1021/jm00116a002
BindingDB Entry DOI: 10.7270/Q2M907M8
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50008650
PNG
((S)-3-(1H-Indol-3-yl)-N,N-dipentyl-2-(3-m-tolyl-ur...)
Show SMILES CCCCCN(CCCCC)C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C29H40N4O2/c1-4-6-10-17-33(18-11-7-5-2)28(34)27(20-23-21-30-26-16-9-8-15-25(23)26)32-29(35)31-24-14-12-13-22(3)19-24/h8-9,12-16,19,21,27,30H,4-7,10-11,17-18,20H2,1-3H3,(H2,31,32,35)/t27-/m0/s1
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n/an/a 1.50E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreatic membranes.


J Med Chem 34: 3350-9 (1992)


Article DOI: 10.1021/jm00116a002
BindingDB Entry DOI: 10.7270/Q2M907M8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50008654
PNG
((R)-2-[3-(4-Chloro-phenyl)-ureido]-3-(1H-indol-3-y...)
Show SMILES CCCCCN(CCCCC)C(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C28H37ClN4O2/c1-3-5-9-17-33(18-10-6-4-2)27(34)26(19-21-20-30-25-12-8-7-11-24(21)25)32-28(35)31-23-15-13-22(29)14-16-23/h7-8,11-16,20,26,30H,3-6,9-10,17-19H2,1-2H3,(H2,31,32,35)/t26-/m1/s1
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n/an/a 5.60E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Bolton-Hunter CCK-8 binding to cholecystokinin type B receptor in guinea pig cerebral cortical.


J Med Chem 34: 3350-9 (1992)


Article DOI: 10.1021/jm00116a002
BindingDB Entry DOI: 10.7270/Q2M907M8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50008651
PNG
((R)-3-(1H-Indol-3-yl)-N,N-dipentyl-2-(3-m-tolyl-ur...)
Show SMILES CCCCCN(CCCCC)C(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C29H40N4O2/c1-4-6-10-17-33(18-11-7-5-2)28(34)27(20-23-21-30-26-16-9-8-15-25(23)26)32-29(35)31-24-14-12-13-22(3)19-24/h8-9,12-16,19,21,27,30H,4-7,10-11,17-18,20H2,1-3H3,(H2,31,32,35)/t27-/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Bolton-Hunter CCK-8 binding to cholecystokinin type B receptor in guinea pig cerebral cortical.


J Med Chem 34: 3350-9 (1992)


Article DOI: 10.1021/jm00116a002
BindingDB Entry DOI: 10.7270/Q2M907M8
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50008654
PNG
((R)-2-[3-(4-Chloro-phenyl)-ureido]-3-(1H-indol-3-y...)
Show SMILES CCCCCN(CCCCC)C(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C28H37ClN4O2/c1-3-5-9-17-33(18-10-6-4-2)27(34)26(19-21-20-30-25-12-8-7-11-24(21)25)32-28(35)31-23-15-13-22(29)14-16-23/h7-8,11-16,20,26,30H,3-6,9-10,17-19H2,1-2H3,(H2,31,32,35)/t26-/m1/s1
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n/an/a 4.20E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreatic membranes.


J Med Chem 34: 3350-9 (1992)


Article DOI: 10.1021/jm00116a002
BindingDB Entry DOI: 10.7270/Q2M907M8
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50008645
PNG
((S)-3-(1H-Indol-3-yl)-N,N-dipentyl-2-(3-p-tolyl-ur...)
Show SMILES CCCCCN(CCCCC)C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Nc1ccc(C)cc1
Show InChI InChI=1S/C29H40N4O2/c1-4-6-10-18-33(19-11-7-5-2)28(34)27(20-23-21-30-26-13-9-8-12-25(23)26)32-29(35)31-24-16-14-22(3)15-17-24/h8-9,12-17,21,27,30H,4-7,10-11,18-20H2,1-3H3,(H2,31,32,35)/t27-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreatic membranes.


J Med Chem 34: 3350-9 (1992)


Article DOI: 10.1021/jm00116a002
BindingDB Entry DOI: 10.7270/Q2M907M8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50008637
PNG
((R)-3-(1H-Indol-3-yl)-N,N-dipentyl-2-(3-p-tolyl-ur...)
Show SMILES CCCCCN(CCCCC)C(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)Nc1ccc(C)cc1
Show InChI InChI=1S/C29H40N4O2/c1-4-6-10-18-33(19-11-7-5-2)28(34)27(20-23-21-30-26-13-9-8-12-25(23)26)32-29(35)31-24-16-14-22(3)15-17-24/h8-9,12-17,21,27,30H,4-7,10-11,18-20H2,1-3H3,(H2,31,32,35)/t27-/m1/s1
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n/an/a 1.90E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Bolton-Hunter CCK-8 binding to cholecystokinin type B receptor in guinea pig cerebral cortical.


J Med Chem 34: 3350-9 (1992)


Article DOI: 10.1021/jm00116a002
BindingDB Entry DOI: 10.7270/Q2M907M8
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50008672
PNG
((S)-2-[3-(4-Chloro-phenyl)-ureido]-3-(1H-indol-3-y...)
Show SMILES CCCCCN(CCCCC)C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C28H37ClN4O2/c1-3-5-9-17-33(18-10-6-4-2)27(34)26(19-21-20-30-25-12-8-7-11-24(21)25)32-28(35)31-23-15-13-22(29)14-16-23/h7-8,11-16,20,26,30H,3-6,9-10,17-19H2,1-2H3,(H2,31,32,35)/t26-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreatic membranes.


J Med Chem 34: 3350-9 (1992)


Article DOI: 10.1021/jm00116a002
BindingDB Entry DOI: 10.7270/Q2M907M8
More data for this
Ligand-Target Pair