BindingDB logo
myBDB logout

55 similar compounds to monomer 50025935

Compile data set for download or QSAR
Wt: 829.0
BDBM50023050
Wt: 771.9
BDBM50016026
Wt: 600.7
BDBM50009619
Wt: 602.7
BDBM50009621
Wt: 602.7
BDBM50009624
Wt: 680.8
BDBM50016035
Wt: 681.8
BDBM50016036
Wt: 735.9
BDBM50016037
Wt: 666.8
BDBM50016041
Wt: 758.0
BDBM50016058
Wt: 774.0
BDBM50016063
Wt: 475.6
BDBM50022627
Wt: 465.5
BDBM50022612
Wt: 505.6
BDBM50022626
Wt: 545.7
BDBM50022609
Displayed 1 to 15 (of 52 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50023050,50016026,50009619,50009621,50009624,50016035,50016036,50016037,50016041,50016058,50016063,50022627,50022612,50022626,50022609   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Renin


(Homo sapiens (Human))
BDBM50023050
PNG
(CHEMBL40928 | {1-[1-(1-{2-[1-(1-Carbamoyl-2-phenyl...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C46H64N6O8/c1-29(2)23-34(39(53)28-40(54)48-36(24-30(3)4)42(56)50-35(41(47)55)25-31-17-11-8-12-18-31)49-43(57)37(26-32-19-13-9-14-20-32)51-44(58)38(27-33-21-15-10-16-22-33)52-45(59)60-46(5,6)7/h8-22,29-30,34-39,53H,23-28H2,1-7H3,(H2,47,55)(H,48,54)(H,49,57)(H,50,56)(H,51,58)(H,52,59)/t34-,35-,36-,37-,38-,39-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.80n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of human kidney renin


J Med Chem 28: 1755-6 (1986)


Article DOI: 10.1021/jm00150a001
BindingDB Entry DOI: 10.7270/Q2P26X56
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50016026
PNG
(CHEMBL424543 | [1-(1-{1-[2-(1-Benzylcarbamoyl-3-me...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(O)CC(=O)N[C@@H](CC(C)C)C(=O)NCc1ccccc1
Show InChI InChI=1S/C44H61N5O7/c1-29(2)23-34(38(50)27-39(51)46-35(24-30(3)4)40(52)45-28-33-21-15-10-16-22-33)47-41(53)36(25-31-17-11-8-12-18-31)48-42(54)37(26-32-19-13-9-14-20-32)49-43(55)56-44(5,6)7/h8-22,29-30,34-38,50H,23-28H2,1-7H3,(H,45,52)(H,46,51)(H,47,53)(H,48,54)(H,49,55)/t34-,35-,36-,37-,38?/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
43n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of human kidney renin


J Med Chem 28: 1755-6 (1986)


Article DOI: 10.1021/jm00150a001
BindingDB Entry DOI: 10.7270/Q2P26X56
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50023050
PNG
(CHEMBL40928 | {1-[1-(1-{2-[1-(1-Carbamoyl-2-phenyl...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C46H64N6O8/c1-29(2)23-34(39(53)28-40(54)48-36(24-30(3)4)42(56)50-35(41(47)55)25-31-17-11-8-12-18-31)49-43(57)37(26-32-19-13-9-14-20-32)51-44(58)38(27-33-21-15-10-16-22-33)52-45(59)60-46(5,6)7/h8-22,29-30,34-39,53H,23-28H2,1-7H3,(H2,47,55)(H,48,54)(H,49,57)(H,50,56)(H,51,58)(H,52,59)/t34-,35-,36-,37-,38-,39-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
52n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for inhibitory activity against human kidney renin


J Med Chem 30: 1617-22 (1987)


Article DOI: 10.1021/jm00392a016
BindingDB Entry DOI: 10.7270/Q2RB73KD
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50016041
PNG
((1-Benzyl-4-{1-[2-(1-benzylcarbamoyl-3-methyl-buty...)
Show SMILES CC(C)C[C@H](NC(=O)CCC[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(O)CC(=O)N[C@@H](CC(C)C)C(=O)NCc1ccccc1
Show InChI InChI=1S/C38H58N4O6/c1-26(2)21-31(33(43)24-35(45)42-32(22-27(3)4)36(46)39-25-29-17-12-9-13-18-29)41-34(44)20-14-19-30(23-28-15-10-8-11-16-28)40-37(47)48-38(5,6)7/h8-13,15-18,26-27,30-33,43H,14,19-25H2,1-7H3,(H,39,46)(H,40,47)(H,41,44)(H,42,45)/t30-,31+,32+,33?/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibitory activity against human renin


J Med Chem 33: 838-45 (1990)


Article DOI: 10.1021/jm00164a058
BindingDB Entry DOI: 10.7270/Q2T152M6
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50016063
PNG
(CHEMBL169023 | {1-Benzyl-2-[(1-{1-[2-(1-benzylcarb...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)N(O)C[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(O)CC(=O)N[C@@H](CC(C)C)C(=O)NCc1ccccc1
Show InChI InChI=1S/C44H63N5O7/c1-30(2)23-36(39(50)27-40(51)47-37(24-31(3)4)41(52)45-28-34-21-15-10-16-22-34)48-42(53)38(26-33-19-13-9-14-20-33)49(55)29-35(25-32-17-11-8-12-18-32)46-43(54)56-44(5,6)7/h8-22,30-31,35-39,50,55H,23-29H2,1-7H3,(H,45,52)(H,46,54)(H,47,51)(H,48,53)/t35-,36-,37-,38-,39?/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibitory activity against human renin


J Med Chem 33: 838-45 (1990)


Article DOI: 10.1021/jm00164a058
BindingDB Entry DOI: 10.7270/Q2T152M6
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50016058
PNG
(CHEMBL168712 | [1-Benzyl-2-(1-{1-[2-(1-benzylcarba...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(O)CC(=O)N[C@@H](CC(C)C)C(=O)NCc1ccccc1
Show InChI InChI=1S/C44H63N5O6/c1-30(2)23-36(39(50)27-40(51)48-38(24-31(3)4)41(52)46-28-34-21-15-10-16-22-34)49-42(53)37(26-33-19-13-9-14-20-33)45-29-35(25-32-17-11-8-12-18-32)47-43(54)55-44(5,6)7/h8-22,30-31,35-39,45,50H,23-29H2,1-7H3,(H,46,52)(H,47,54)(H,48,51)(H,49,53)/t35-,36-,37-,38-,39?/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.20E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibitory activity against human renin


J Med Chem 33: 838-45 (1990)


Article DOI: 10.1021/jm00164a058
BindingDB Entry DOI: 10.7270/Q2T152M6
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50009619
PNG
(CHEMBL91847 | [1-(13-Cyclohexylmethyl-12-hydroxy-2...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCC(=O)NCCCC(=O)[C@H](O)[C@H](CC2CCCCC2)NC1=O
Show InChI InChI=1S/C32H48N4O7/c1-32(2,3)43-31(42)36-25(20-22-13-8-5-9-14-22)30(41)34-23-16-17-27(38)33-18-10-15-26(37)28(39)24(35-29(23)40)19-21-11-6-4-7-12-21/h5,8-9,13-14,21,23-25,28,39H,4,6-7,10-12,15-20H2,1-3H3,(H,33,38)(H,34,41)(H,35,40)(H,36,42)/t23-,24-,25-,28+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40E+4n/an/an/an/a7.4n/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
The compound was evaluated in vitro for inhibition of human plasma renin at pH 7.4.


J Med Chem 34: 2692-701 (1991)


Article DOI: 10.1021/jm00113a005
BindingDB Entry DOI: 10.7270/Q2P26X4R
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50009621
PNG
(CHEMBL90266 | [1-(13-Cyclohexylmethyl-11,12-dihydr...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCC(=O)NCCC[C@H](O)[C@H](O)[C@H](CC2CCCCC2)NC1=O
Show InChI InChI=1S/C32H50N4O7/c1-32(2,3)43-31(42)36-25(20-22-13-8-5-9-14-22)30(41)34-23-16-17-27(38)33-18-10-15-26(37)28(39)24(35-29(23)40)19-21-11-6-4-7-12-21/h5,8-9,13-14,21,23-26,28,37,39H,4,6-7,10-12,15-20H2,1-3H3,(H,33,38)(H,34,41)(H,35,40)(H,36,42)/t23-,24-,25-,26-,28+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 650n/an/an/an/a7.4n/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
The compound was evaluated in vitro for inhibition of human plasma renin at pH 7.4.


J Med Chem 34: 2692-701 (1991)


Article DOI: 10.1021/jm00113a005
BindingDB Entry DOI: 10.7270/Q2P26X4R
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50009624
PNG
(CHEMBL327811 | [1-(13-Cyclohexylmethyl-11,12-dihyd...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCC(=O)NCCC[C@@H](O)[C@H](O)[C@H](CC2CCCCC2)NC1=O
Show InChI InChI=1S/C32H50N4O7/c1-32(2,3)43-31(42)36-25(20-22-13-8-5-9-14-22)30(41)34-23-16-17-27(38)33-18-10-15-26(37)28(39)24(35-29(23)40)19-21-11-6-4-7-12-21/h5,8-9,13-14,21,23-26,28,37,39H,4,6-7,10-12,15-20H2,1-3H3,(H,33,38)(H,34,41)(H,35,40)(H,36,42)/t23-,24-,25-,26+,28+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+4n/an/an/an/a7.4n/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
The compound was evaluated in vitro for inhibition of human plasma renin at pH 7.4.


J Med Chem 34: 2692-701 (1991)


Article DOI: 10.1021/jm00113a005
BindingDB Entry DOI: 10.7270/Q2P26X4R
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50022609
PNG
(CHEMBL3142282 | CHEMBL73743 | {1-[1-(1-Cyclohexylm...)
Show SMILES CC(C)CC[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C31H51N3O5/c1-21(2)17-18-27(35)25(19-23-13-9-7-10-14-23)33-28(36)22(3)32-29(37)26(20-24-15-11-8-12-16-24)34-30(38)39-31(4,5)6/h8,11-12,15-16,21-23,25-27,35H,7,9-10,13-14,17-20H2,1-6H3,(H,32,37)(H,33,36)(H,34,38)/t22-,25-,26-,27-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against renin


J Med Chem 31: 2264-76 (1989)


Article DOI: 10.1021/jm00120a005
BindingDB Entry DOI: 10.7270/Q2T72GDD
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50022612
PNG
((1-{1-[1-(1,2-Dihydroxy-ethyl)-3-methyl-butylcarba...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)[C@@H](O)CO
Show InChI InChI=1S/C24H39N3O6/c1-15(2)12-18(20(29)14-28)26-21(30)16(3)25-22(31)19(13-17-10-8-7-9-11-17)27-23(32)33-24(4,5)6/h7-11,15-16,18-20,28-29H,12-14H2,1-6H3,(H,25,31)(H,26,30)(H,27,32)/t16-,18-,19-,20-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against renin


J Med Chem 31: 2264-76 (1989)


Article DOI: 10.1021/jm00120a005
BindingDB Entry DOI: 10.7270/Q2T72GDD
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50022626
PNG
(CHEMBL3142287 | CHEMBL72373 | {1-[1-(1-Cyclohexylm...)
Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CO
Show InChI InChI=1S/C27H43N3O6/c1-18(24(33)29-21(23(32)17-31)15-19-11-7-5-8-12-19)28-25(34)22(16-20-13-9-6-10-14-20)30-26(35)36-27(2,3)4/h6,9-10,13-14,18-19,21-23,31-32H,5,7-8,11-12,15-17H2,1-4H3,(H,28,34)(H,29,33)(H,30,35)/t18-,21-,22-,23-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 350n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against renin


J Med Chem 31: 2264-76 (1989)


Article DOI: 10.1021/jm00120a005
BindingDB Entry DOI: 10.7270/Q2T72GDD
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50022627
PNG
(CHEMBL3142272 | CHEMBL422590 | {1-[1-(2-Cyclohexyl...)
Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@H](CO)CC1CCCCC1
Show InChI InChI=1/C26H41N3O5/c1-18(23(31)28-21(17-30)15-19-11-7-5-8-12-19)27-24(32)22(16-20-13-9-6-10-14-20)29-25(33)34-26(2,3)4/h6,9-10,13-14,18-19,21-22,30H,5,7-8,11-12,15-17H2,1-4H3,(H,27,32)(H,28,31)(H,29,33)/t18-,21-,22-/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against renin


J Med Chem 31: 2264-76 (1989)


Article DOI: 10.1021/jm00120a005
BindingDB Entry DOI: 10.7270/Q2T72GDD
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50016037
PNG
((4-{3-[1-(3-Aminomethyl-benzylcarbamoyl)-3-methyl-...)
Show SMILES CC(C)C[C@H](NC(=O)C[C@@H](O)C(CC1CCCCC1)NC(=O)CCC[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NCc1cccc(CN)c1
Show InChI InChI=1S/C42H65N5O6/c1-29(2)22-36(40(51)44-28-33-19-12-18-32(23-33)27-43)47-39(50)26-37(48)35(25-31-16-10-7-11-17-31)46-38(49)21-13-20-34(24-30-14-8-6-9-15-30)45-41(52)53-42(3,4)5/h6,8-9,12,14-15,18-19,23,29,31,34-37,48H,7,10-11,13,16-17,20-22,24-28,43H2,1-5H3,(H,44,51)(H,45,52)(H,46,49)(H,47,50)/t34-,35?,36+,37-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 630n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibitory activity against human renin


J Med Chem 33: 838-45 (1990)


Article DOI: 10.1021/jm00164a058
BindingDB Entry DOI: 10.7270/Q2T152M6
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50016036
PNG
(CHEMBL167930 | {1-[({1-[2-(1-Benzylcarbamoyl-3-met...)
Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(O)CC(=O)N[C@@H](CC(C)C)C(=O)NCc1ccccc1
Show InChI InChI=1S/C37H55N5O7/c1-24(2)18-28(31(43)21-32(44)41-29(19-25(3)4)34(46)38-22-27-16-12-9-13-17-27)40-33(45)23-39-35(47)30(20-26-14-10-8-11-15-26)42-36(48)49-37(5,6)7/h8-17,24-25,28-31,43H,18-23H2,1-7H3,(H,38,46)(H,39,47)(H,40,45)(H,41,44)(H,42,48)/t28-,29-,30-,31?/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
The compound was tested in vitro for inhibitory activity against Renin in monkey plasma


J Med Chem 33: 838-45 (1990)


Article DOI: 10.1021/jm00164a058
BindingDB Entry DOI: 10.7270/Q2T152M6
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50016026
PNG
(CHEMBL424543 | [1-(1-{1-[2-(1-Benzylcarbamoyl-3-me...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(O)CC(=O)N[C@@H](CC(C)C)C(=O)NCc1ccccc1
Show InChI InChI=1S/C44H61N5O7/c1-29(2)23-34(38(50)27-39(51)46-35(24-30(3)4)40(52)45-28-33-21-15-10-16-22-33)47-41(53)36(25-31-17-11-8-12-18-31)48-42(54)37(26-32-19-13-9-14-20-32)49-43(55)56-44(5,6)7/h8-22,29-30,34-38,50H,23-28H2,1-7H3,(H,45,52)(H,46,51)(H,47,53)(H,48,54)(H,49,55)/t34-,35-,36-,37-,38?/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibitory activity against human renin


J Med Chem 33: 838-45 (1990)


Article DOI: 10.1021/jm00164a058
BindingDB Entry DOI: 10.7270/Q2T152M6
More data for this
Ligand-Target Pair
Renin


(Homo sapiens (Human))
BDBM50016035
PNG
((1-Benzyl-4-{1-[2-(1-benzylcarbamoyl-3-methyl-buty...)
Show SMILES CC(C)C[C@H](NC(=O)CCC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(O)CC(=O)N[C@@H](CC(C)C)C(=O)NCc1ccccc1
Show InChI InChI=1S/C38H56N4O7/c1-25(2)20-29(33(44)23-35(46)41-31(21-26(3)4)36(47)39-24-28-16-12-9-13-17-28)40-34(45)19-18-32(43)30(22-27-14-10-8-11-15-27)42-37(48)49-38(5,6)7/h8-17,25-26,29-31,33,44H,18-24H2,1-7H3,(H,39,47)(H,40,45)(H,41,46)(H,42,48)/t29-,30-,31-,33?/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.10E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibitory activity against human renin


J Med Chem 33: 838-45 (1990)


Article DOI: 10.1021/jm00164a058
BindingDB Entry DOI: 10.7270/Q2T152M6
More data for this
Ligand-Target Pair