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3 similar compounds to monomer 50406486

Compile data set for download or QSAR
Wt: 325.3
BDBM50009853
Wt: 311.3
BDBM50009858
Wt: 311.3
BDBM50368232

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009853,50009858,50368232   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009853
PNG
(2-[3-(2-Fluoro-benzoyl)-2-methyl-indol-1-yl]-propi...)
Show SMILES CC(C(O)=O)n1c(C)c(C(=O)c2ccccc2F)c2ccccc12
Show InChI InChI=1/C19H16FNO3/c1-11-17(18(22)13-7-3-5-9-15(13)20)14-8-4-6-10-16(14)21(11)12(2)19(23)24/h3-10,12H,1-2H3,(H,23,24)
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Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50368232
PNG
(CHEMBL1907834)
Show SMILES C[C@@H](C(O)=O)n1cc(C(=O)c2ccccc2F)c2ccccc12
Show InChI InChI=1/C18H14FNO3/c1-11(18(22)23)20-10-14(12-6-3-5-9-16(12)20)17(21)13-7-2-4-8-15(13)19/h2-11H,1H3,(H,22,23)/t11-/s2
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PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009858
PNG
((R) 2-[3-(2-Fluoro-benzoyl)-indol-1-yl]-propionic ...)
Show SMILES CC(C(O)=O)n1cc(C(=O)c2ccccc2F)c2ccccc12
Show InChI InChI=1/C18H14FNO3/c1-11(18(22)23)20-10-14(12-6-3-5-9-16(12)20)17(21)13-7-2-4-8-15(13)19/h2-11H,1H3,(H,22,23)
PDB
MMDB

Reactome pathway
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GoogleScholar
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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 300n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair