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13 similar compounds to monomer 50009992

Compile data set for download or QSAR
Wt: 270.2
BDBM50009979
Wt: 305.3
BDBM50009980
Wt: 305.3
BDBM50009981
Wt: 285.2
BDBM50009983
Wt: 273.2
BDBM50009984
Wt: 312.3
BDBM50009990
Wt: 255.2
BDBM50009997
Purchase
Wt: 374.3
BDBM50010002
Wt: 289.7
BDBM50016600
Wt: 285.2
BDBM50016604
Wt: 305.3
BDBM50016615
Wt: 305.3
BDBM50016619
Wt: 269.2
BDBM50016596

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50009979,50009980,50009981,50009983,50009984,50009990,50009997,50010002,50016600,50016604,50016615,50016619,50016596   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase


(Rattus norvegicus)
BDBM50009979
PNG
(CHEMBL67330 | [(4-Amino-benzoyl)-phenyl-amino]-ace...)
Show SMILES Nc1ccc(cc1)C(=O)N(CC(O)=O)c1ccccc1
Show InChI InChI=1S/C15H14N2O3/c16-12-8-6-11(7-9-12)15(20)17(10-14(18)19)13-4-2-1-3-5-13/h1-9H,10,16H2,(H,18,19)
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n/an/a 1.20E+4n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50016619
PNG
((Benzoyl-naphthalen-2-yl-amino)-acetic acid | CHEM...)
Show SMILES OC(=O)CN(C(=O)c1ccccc1)c1ccc2ccccc2c1
Show InChI InChI=1S/C19H15NO3/c21-18(22)13-20(19(23)15-7-2-1-3-8-15)17-11-10-14-6-4-5-9-16(14)12-17/h1-12H,13H2,(H,21,22)
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n/an/a 2.20E+5n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibition of aldose reductase from rat lens. Value ranges from 40 - 680


J Med Chem 32: 1033-8 (1989)


Article DOI: 10.1021/jm00125a017
BindingDB Entry DOI: 10.7270/Q2CV4GQC
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50009981
PNG
(CHEMBL305492 | [(Naphthalene-2-carbonyl)-phenyl-am...)
Show SMILES OC(=O)CN(C(=O)c1ccc2ccccc2c1)c1ccccc1
Show InChI InChI=1S/C19H15NO3/c21-18(22)13-20(17-8-2-1-3-9-17)19(23)16-11-10-14-6-4-5-7-15(14)12-16/h1-12H,13H2,(H,21,22)
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n/an/a 1.90E+4n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50009983
PNG
(CHEMBL308898 | [(4-Methoxy-benzoyl)-phenyl-amino]-...)
Show SMILES COc1ccc(cc1)C(=O)N(CC(O)=O)c1ccccc1
Show InChI InChI=1S/C16H15NO4/c1-21-14-9-7-12(8-10-14)16(20)17(11-15(18)19)13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,18,19)
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n/an/a 3.20E+3n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50009984
PNG
(CHEMBL66216 | [(4-Fluoro-benzoyl)-phenyl-amino]-ac...)
Show SMILES OC(=O)CN(C(=O)c1ccc(F)cc1)c1ccccc1
Show InChI InChI=1S/C15H12FNO3/c16-12-8-6-11(7-9-12)15(20)17(10-14(18)19)13-4-2-1-3-5-13/h1-9H,10H2,(H,18,19)
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n/an/a 8.20E+3n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50009990
PNG
(CHEMBL305251 | [(4-Benzoylamino-benzoyl)-methyl-am...)
Show SMILES CN(CC(O)=O)C(=O)c1ccc(NC(=O)c2ccccc2)cc1
Show InChI InChI=1S/C17H16N2O4/c1-19(11-15(20)21)17(23)13-7-9-14(10-8-13)18-16(22)12-5-3-2-4-6-12/h2-10H,11H2,1H3,(H,18,22)(H,20,21)
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n/an/a 2.80E+3n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50009997
PNG
((Benzoyl-phenyl-amino)-acetic acid | CHEMBL273228)
Show SMILES OC(=O)CN(C(=O)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C15H13NO3/c17-14(18)11-16(13-9-5-2-6-10-13)15(19)12-7-3-1-4-8-12/h1-10H,11H2,(H,17,18)
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n/an/a 6.30E+3n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50010002
PNG
(CHEMBL302057 | [(4-Benzoylamino-benzoyl)-phenyl-am...)
Show SMILES OC(=O)CN(C(=O)c1ccc(NC(=O)c2ccccc2)cc1)c1ccccc1
Show InChI InChI=1S/C22H18N2O4/c25-20(26)15-24(19-9-5-2-6-10-19)22(28)17-11-13-18(14-12-17)23-21(27)16-7-3-1-4-8-16/h1-14H,15H2,(H,23,27)(H,25,26)
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n/an/a 240n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50009997
PNG
((Benzoyl-phenyl-amino)-acetic acid | CHEMBL273228)
Show SMILES OC(=O)CN(C(=O)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C15H13NO3/c17-14(18)11-16(13-9-5-2-6-10-13)15(19)12-7-3-1-4-8-12/h1-10H,11H2,(H,17,18)
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n/an/a 9.50E+3n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibition of aldose reductase from rat lens. Value ranges from 6 - 14


J Med Chem 32: 1033-8 (1989)


Article DOI: 10.1021/jm00125a017
BindingDB Entry DOI: 10.7270/Q2CV4GQC
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50016596
PNG
((Benzoyl-p-tolyl-amino)-acetic acid | CHEMBL275007)
Show SMILES Cc1ccc(cc1)N(CC(O)=O)C(=O)c1ccccc1
Show InChI InChI=1S/C16H15NO3/c1-12-7-9-14(10-8-12)17(11-15(18)19)16(20)13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,18,19)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibition of aldose reductase from rat lens. Value ranges from 0.5 - 16


J Med Chem 32: 1033-8 (1989)


Article DOI: 10.1021/jm00125a017
BindingDB Entry DOI: 10.7270/Q2CV4GQC
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50016604
PNG
(CHEMBL267531 | [Benzoyl-(4-methoxy-phenyl)-amino]-...)
Show SMILES COc1ccc(cc1)N(CC(O)=O)C(=O)c1ccccc1
Show InChI InChI=1S/C16H15NO4/c1-21-14-9-7-13(8-10-14)17(11-15(18)19)16(20)12-5-3-2-4-6-12/h2-10H,11H2,1H3,(H,18,19)
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n/an/a 960n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibition of aldose reductase from rat lens. Value ranges from 0.1 - 7


J Med Chem 32: 1033-8 (1989)


Article DOI: 10.1021/jm00125a017
BindingDB Entry DOI: 10.7270/Q2CV4GQC
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50009980
PNG
(CHEMBL266688 | [(Naphthalene-1-carbonyl)-phenyl-am...)
Show SMILES OC(=O)CN(C(=O)c1cccc2ccccc12)c1ccccc1
Show InChI InChI=1S/C19H15NO3/c21-18(22)13-20(15-9-2-1-3-10-15)19(23)17-12-6-8-14-7-4-5-11-16(14)17/h1-12H,13H2,(H,21,22)
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n/an/a 5.80E+3n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibition of aldose reductase from rat lens. Value ranges from 1.0 - 34


J Med Chem 32: 1033-8 (1989)


Article DOI: 10.1021/jm00125a017
BindingDB Entry DOI: 10.7270/Q2CV4GQC
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50016600
PNG
(CHEMBL274433 | [Benzoyl-(4-chloro-phenyl)-amino]-a...)
Show SMILES OC(=O)CN(C(=O)c1ccccc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C15H12ClNO3/c16-12-6-8-13(9-7-12)17(10-14(18)19)15(20)11-4-2-1-3-5-11/h1-9H,10H2,(H,18,19)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibition of aldose reductase from rat lens. Value ranges from 1.5 - 16


J Med Chem 32: 1033-8 (1989)


Article DOI: 10.1021/jm00125a017
BindingDB Entry DOI: 10.7270/Q2CV4GQC
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50016615
PNG
((Benzoyl-naphthalen-1-yl-amino)-acetic acid | CHEM...)
Show SMILES OC(=O)CN(C(=O)c1ccccc1)c1cccc2ccccc12
Show InChI InChI=1S/C19H15NO3/c21-18(22)13-20(19(23)15-8-2-1-3-9-15)17-12-6-10-14-7-4-5-11-16(14)17/h1-12H,13H2,(H,21,22)
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n/an/a 2.30E+5n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibition of aldose reductase from rat lens. Value ranges from 50 - 650


J Med Chem 32: 1033-8 (1989)


Article DOI: 10.1021/jm00125a017
BindingDB Entry DOI: 10.7270/Q2CV4GQC
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50009980
PNG
(CHEMBL266688 | [(Naphthalene-1-carbonyl)-phenyl-am...)
Show SMILES OC(=O)CN(C(=O)c1cccc2ccccc12)c1ccccc1
Show InChI InChI=1S/C19H15NO3/c21-18(22)13-20(15-9-2-1-3-10-15)19(23)17-12-6-8-14-7-4-5-11-16(14)17/h1-12H,13H2,(H,21,22)
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n/an/a 8.50E+3n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair