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5 similar compounds to monomer 50009989

Compile data set for download or QSAR
Wt: 229.2
BDBM50009982
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Wt: 207.2
BDBM50009987
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Wt: 243.2
BDBM50009991
Wt: 229.2
BDBM50009995
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Wt: 193.1
BDBM50009998
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50009982,50009987,50009991,50009995,50009998   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase


(Rattus norvegicus)
BDBM50009982
PNG
(CHEMBL8798 | [(Naphthalene-2-carbonyl)-amino]-acet...)
Show SMILES OC(=O)CNC(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C13H11NO3/c15-12(16)8-14-13(17)11-6-5-9-3-1-2-4-10(9)7-11/h1-7H,8H2,(H,14,17)(H,15,16)
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Article
PubMed
n/an/a 7.00E+4n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50009987
PNG
(CHEMBL67014 | [Methyl-(4-methyl-benzoyl)-amino]-ac...)
Show SMILES CN(CC(O)=O)C(=O)c1ccc(C)cc1
Show InChI InChI=1S/C11H13NO3/c1-8-3-5-9(6-4-8)11(15)12(2)7-10(13)14/h3-6H,7H2,1-2H3,(H,13,14)
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PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50009982
PNG
(CHEMBL8798 | [(Naphthalene-2-carbonyl)-amino]-acet...)
Show SMILES OC(=O)CNC(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C13H11NO3/c15-12(16)8-14-13(17)11-6-5-9-3-1-2-4-10(9)7-11/h1-7H,8H2,(H,14,17)(H,15,16)
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PubMed
n/an/a 4.00E+4n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibition of aldose reductase from rat lens. Value ranges from 25-64


J Med Chem 32: 1033-8 (1989)


Article DOI: 10.1021/jm00125a017
BindingDB Entry DOI: 10.7270/Q2CV4GQC
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50009995
PNG
(2-(1-naphthamido)acetate | CHEMBL306898 | [(Naphth...)
Show SMILES OC(=O)CNC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C13H11NO3/c15-12(16)8-14-13(17)11-7-3-5-9-4-1-2-6-10(9)11/h1-7H,8H2,(H,14,17)(H,15,16)
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Article
PubMed
n/an/a 2.20E+5n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50009998
PNG
((Benzoyl-methyl-amino)-acetic acid | CHEMBL66391)
Show SMILES CN(CC(O)=O)C(=O)c1ccccc1
Show InChI InChI=1S/C10H11NO3/c1-11(7-9(12)13)10(14)8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,12,13)
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Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50009991
PNG
(CHEMBL67731 | [Methyl-(naphthalene-2-carbonyl)-ami...)
Show SMILES CN(CC(O)=O)C(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C14H13NO3/c1-15(9-13(16)17)14(18)12-7-6-10-4-2-3-5-11(10)8-12/h2-8H,9H2,1H3,(H,16,17)
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Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair