BindingDB logo
myBDB logout

7 similar compounds to monomer 50016529

Compile data set for download or QSAR
Wt: 226.2
BDBM50010079
Purchase
Wt: 256.2
BDBM50010084
Wt: 460.9
BDBM50016530
Wt: 460.9
BDBM50016531
Wt: 460.9
BDBM50016532
Wt: 460.9
BDBM50016536
Wt: 460.9
BDBM50016537

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50010079,50010084,50016530,50016531,50016532,50016536,50016537   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acrosin


(Sus scrofa)
BDBM50010084
PNG
(CHEMBL2418047)
Show SMILES COc1ccc(OCc2ccc(cc2)C(N)=N)cc1
Show InChI InChI=1S/C15H16N2O2/c1-18-13-6-8-14(9-7-13)19-10-11-2-4-12(5-3-11)15(16)17/h2-9H,10H2,1H3,(H3,16,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.60E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Reversible competitive inhibition of boar spermatozoa acrosin using BzArgOEt as substrate by Dixon plot analysis


J Med Chem 21: 1132-6 (1979)


Article DOI: 10.1021/jm00209a008
BindingDB Entry DOI: 10.7270/Q2TT4SGN
More data for this
Ligand-Target Pair
Glandular kallikrein


(Sus scrofa)
BDBM50016530
PNG
(CHEMBL3277927)
Show SMILES NC(=N)c1cccc(COc2cccc3c(OCc4cccc(c4)C(N)=N)cccc23)c1
Show InChI InChI=1S/C26H24N4O2.ClH/c27-25(28)19-7-1-5-17(13-19)15-31-23-11-3-10-22-21(23)9-4-12-24(22)32-16-18-6-2-8-20(14-18)26(29)30;/h1-14H,15-16H2,(H3,27,28)(H3,29,30);1H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.20E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of porcine pancreatic kallikrein using BANA as substrate after 15 to 180 mins


J Med Chem 19: 634-9 (1976)


Article DOI: 10.1021/jm00227a011
BindingDB Entry DOI: 10.7270/Q2KD20FM
More data for this
Ligand-Target Pair
Thrombin


(Bos taurus (Bovine))
BDBM50016532
PNG
(CHEMBL3277929)
Show SMILES NC(=N)c1cccc(COc2ccc3cc(OCc4cccc(c4)C(N)=N)ccc3c2)c1
Show InChI InChI=1S/C26H24N4O2.ClH/c27-25(28)21-5-1-3-17(11-21)15-31-23-9-7-20-14-24(10-8-19(20)13-23)32-16-18-4-2-6-22(12-18)26(29)30;/h1-14H,15-16H2,(H3,27,28)(H3,29,30);1H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.40E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of amidase activity of bovine thrombin using BANA as substrate after 15 to 40 mins


J Med Chem 19: 634-9 (1976)


Article DOI: 10.1021/jm00227a011
BindingDB Entry DOI: 10.7270/Q2KD20FM
More data for this
Ligand-Target Pair
Glandular kallikrein


(Sus scrofa)
BDBM50016537
PNG
(CHEMBL3277932)
Show SMILES NC(=N)c1ccc(OCc2ccc(COc3ccc(cc3)C(N)=N)c3ccccc23)cc1
Show InChI InChI=1S/C26H24N4O2.ClH/c27-25(28)17-7-11-21(12-8-17)31-15-19-5-6-20(24-4-2-1-3-23(19)24)16-32-22-13-9-18(10-14-22)26(29)30;/h1-14H,15-16H2,(H3,27,28)(H3,29,30);1H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.50E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of porcine pancreatic kallikrein using BANA as substrate after 15 to 180 mins


J Med Chem 19: 634-9 (1976)


Article DOI: 10.1021/jm00227a011
BindingDB Entry DOI: 10.7270/Q2KD20FM
More data for this
Ligand-Target Pair
Acrosin


(Sus scrofa)
BDBM50010079
PNG
(CHEMBL2418043)
Show SMILES NC(=N)c1ccc(COc2ccccc2)cc1
Show InChI InChI=1S/C14H14N2O/c15-14(16)12-8-6-11(7-9-12)10-17-13-4-2-1-3-5-13/h1-9H,10H2,(H3,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
2.60E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Reversible competitive inhibition of boar spermatozoa acrosin using BzArgOEt as substrate by Dixon plot analysis


J Med Chem 21: 1132-6 (1979)


Article DOI: 10.1021/jm00209a008
BindingDB Entry DOI: 10.7270/Q2TT4SGN
More data for this
Ligand-Target Pair
Glandular kallikrein


(Sus scrofa)
BDBM50016536
PNG
(CHEMBL3277931)
Show SMILES NC(=N)c1ccc(COc2ccc3ccc(OCc4ccc(cc4)C(N)=N)cc3c2)cc1
Show InChI InChI=1S/C26H24N4O2.ClH/c27-25(28)20-5-1-17(2-6-20)15-31-23-11-9-19-10-12-24(14-22(19)13-23)32-16-18-3-7-21(8-4-18)26(29)30;/h1-14H,15-16H2,(H3,27,28)(H3,29,30);1H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.80E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of porcine pancreatic kallikrein using BANA as substrate after 15 to 180 mins


J Med Chem 19: 634-9 (1976)


Article DOI: 10.1021/jm00227a011
BindingDB Entry DOI: 10.7270/Q2KD20FM
More data for this
Ligand-Target Pair
Thrombin


(Bos taurus (Bovine))
BDBM50016530
PNG
(CHEMBL3277927)
Show SMILES NC(=N)c1cccc(COc2cccc3c(OCc4cccc(c4)C(N)=N)cccc23)c1
Show InChI InChI=1S/C26H24N4O2.ClH/c27-25(28)19-7-1-5-17(13-19)15-31-23-11-3-10-22-21(23)9-4-12-24(22)32-16-18-6-2-8-20(14-18)26(29)30;/h1-14H,15-16H2,(H3,27,28)(H3,29,30);1H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.90E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of amidase activity of bovine thrombin using BANA as substrate after 15 to 40 mins


J Med Chem 19: 634-9 (1976)


Article DOI: 10.1021/jm00227a011
BindingDB Entry DOI: 10.7270/Q2KD20FM
More data for this
Ligand-Target Pair
Thrombin


(Bos taurus (Bovine))
BDBM50016536
PNG
(CHEMBL3277931)
Show SMILES NC(=N)c1ccc(COc2ccc3ccc(OCc4ccc(cc4)C(N)=N)cc3c2)cc1
Show InChI InChI=1S/C26H24N4O2.ClH/c27-25(28)20-5-1-17(2-6-20)15-31-23-11-9-19-10-12-24(14-22(19)13-23)32-16-18-3-7-21(8-4-18)26(29)30;/h1-14H,15-16H2,(H3,27,28)(H3,29,30);1H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.90E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of amidase activity of bovine thrombin using BANA as substrate after 15 to 40 mins


J Med Chem 19: 634-9 (1976)


Article DOI: 10.1021/jm00227a011
BindingDB Entry DOI: 10.7270/Q2KD20FM
More data for this
Ligand-Target Pair
Glandular kallikrein


(Sus scrofa)
BDBM50016532
PNG
(CHEMBL3277929)
Show SMILES NC(=N)c1cccc(COc2ccc3cc(OCc4cccc(c4)C(N)=N)ccc3c2)c1
Show InChI InChI=1S/C26H24N4O2.ClH/c27-25(28)21-5-1-3-17(11-21)15-31-23-9-7-20-14-24(10-8-19(20)13-23)32-16-18-4-2-6-22(12-18)26(29)30;/h1-14H,15-16H2,(H3,27,28)(H3,29,30);1H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.50E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of porcine pancreatic kallikrein using BANA as substrate after 15 to 180 mins


J Med Chem 19: 634-9 (1976)


Article DOI: 10.1021/jm00227a011
BindingDB Entry DOI: 10.7270/Q2KD20FM
More data for this
Ligand-Target Pair
Thrombin


(Bos taurus (Bovine))
BDBM50016531
PNG
(CHEMBL3277928)
Show SMILES NC(=N)c1ccc(COc2ccc3cc(OCc4ccc(cc4)C(N)=N)ccc3c2)cc1
Show InChI InChI=1S/C26H24N4O2.ClH/c27-25(28)19-5-1-17(2-6-19)15-31-23-11-9-22-14-24(12-10-21(22)13-23)32-16-18-3-7-20(8-4-18)26(29)30;/h1-14H,15-16H2,(H3,27,28)(H3,29,30);1H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.00E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of amidase activity of bovine thrombin using BANA as substrate after 15 to 40 mins


J Med Chem 19: 634-9 (1976)


Article DOI: 10.1021/jm00227a011
BindingDB Entry DOI: 10.7270/Q2KD20FM
More data for this
Ligand-Target Pair
Thrombin


(Bos taurus (Bovine))
BDBM50016537
PNG
(CHEMBL3277932)
Show SMILES NC(=N)c1ccc(OCc2ccc(COc3ccc(cc3)C(N)=N)c3ccccc23)cc1
Show InChI InChI=1S/C26H24N4O2.ClH/c27-25(28)17-7-11-21(12-8-17)31-15-19-5-6-20(24-4-2-1-3-23(19)24)16-32-22-13-9-18(10-14-22)26(29)30;/h1-14H,15-16H2,(H3,27,28)(H3,29,30);1H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.60E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of amidase activity of bovine thrombin using BANA as substrate after 15 to 40 mins


J Med Chem 19: 634-9 (1976)


Article DOI: 10.1021/jm00227a011
BindingDB Entry DOI: 10.7270/Q2KD20FM
More data for this
Ligand-Target Pair
Glandular kallikrein


(Sus scrofa)
BDBM50016531
PNG
(CHEMBL3277928)
Show SMILES NC(=N)c1ccc(COc2ccc3cc(OCc4ccc(cc4)C(N)=N)ccc3c2)cc1
Show InChI InChI=1S/C26H24N4O2.ClH/c27-25(28)19-5-1-17(2-6-19)15-31-23-11-9-22-14-24(12-10-21(22)13-23)32-16-18-3-7-20(8-4-18)26(29)30;/h1-14H,15-16H2,(H3,27,28)(H3,29,30);1H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
9.70E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of porcine pancreatic kallikrein using BANA as substrate after 15 to 180 mins


J Med Chem 19: 634-9 (1976)


Article DOI: 10.1021/jm00227a011
BindingDB Entry DOI: 10.7270/Q2KD20FM
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50016530
PNG
(CHEMBL3277927)
Show SMILES NC(=N)c1cccc(COc2cccc3c(OCc4cccc(c4)C(N)=N)cccc23)c1
Show InChI InChI=1S/C26H24N4O2.ClH/c27-25(28)19-7-1-5-17(13-19)15-31-23-11-3-10-22-21(23)9-4-12-24(22)32-16-18-6-2-8-20(14-18)26(29)30;/h1-14H,15-16H2,(H3,27,28)(H3,29,30);1H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human thrombin-mediated blood clotting formation in presence of human fibrinogen


J Med Chem 19: 634-9 (1976)


Article DOI: 10.1021/jm00227a011
BindingDB Entry DOI: 10.7270/Q2KD20FM
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50016532
PNG
(CHEMBL3277929)
Show SMILES NC(=N)c1cccc(COc2ccc3cc(OCc4cccc(c4)C(N)=N)ccc3c2)c1
Show InChI InChI=1S/C26H24N4O2.ClH/c27-25(28)21-5-1-3-17(11-21)15-31-23-9-7-20-14-24(10-8-19(20)13-23)32-16-18-4-2-6-22(12-18)26(29)30;/h1-14H,15-16H2,(H3,27,28)(H3,29,30);1H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human thrombin-mediated blood clotting formation in presence of human fibrinogen


J Med Chem 19: 634-9 (1976)


Article DOI: 10.1021/jm00227a011
BindingDB Entry DOI: 10.7270/Q2KD20FM
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50016536
PNG
(CHEMBL3277931)
Show SMILES NC(=N)c1ccc(COc2ccc3ccc(OCc4ccc(cc4)C(N)=N)cc3c2)cc1
Show InChI InChI=1S/C26H24N4O2.ClH/c27-25(28)20-5-1-17(2-6-20)15-31-23-11-9-19-10-12-24(14-22(19)13-23)32-16-18-3-7-21(8-4-18)26(29)30;/h1-14H,15-16H2,(H3,27,28)(H3,29,30);1H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human thrombin-mediated blood clotting formation in presence of human fibrinogen


J Med Chem 19: 634-9 (1976)


Article DOI: 10.1021/jm00227a011
BindingDB Entry DOI: 10.7270/Q2KD20FM
More data for this
Ligand-Target Pair