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82 similar compounds to monomer 50034342

Compile data set for download or QSAR
Wt: 231.3
BDBM50455999
Wt: 245.3
BDBM50455994
Wt: 243.3
BDBM50455993
Wt: 229.3
BDBM50455996
Wt: 245.3
BDBM50455995
Wt: 229.3
BDBM50455997
Wt: 203.2
BDBM50452344
Wt: 245.3
BDBM50452345
Wt: 245.3
BDBM50452347
Wt: 245.3
BDBM50011246
Wt: 245.3
BDBM50011248
Wt: 245.3
BDBM50011249
Wt: 245.3
BDBM50011251
Wt: 261.4
BDBM50011252
Wt: 245.3
BDBM50011253
Displayed 1 to 15 (of 81 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50455999,50455994,50455993,50455996,50455995,50455997,50452344,50452345,50452347,50011246,50011248,50011249,50011251,50011252,50011253   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 1 (5-HT1) receptor


(Rattus norvegicus (rat))
BDBM50011252
PNG
(7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphth...)
Show SMILES CCCN(CCC)[C@H]1CCc2cccc(O)c2[C@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-11-18(12-5-2)15-10-9-14-7-6-8-16(19)17(14)13(15)3/h6-8,13,15,19H,4-5,9-12H2,1-3H3/t13-,15-/m0/s1
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2.80n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011246
PNG
(4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quin...)
Show SMILES CCCN1CCC[C@@H]2[C@@H]1CCc1cccc(O)c21
Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-14(17)9-8-12-5-3-7-15(18)16(12)13/h3,5,7,13-14,18H,2,4,6,8-11H2,1H3/t13-,14+/m1/s1
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3.90n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50455993
PNG
(CHEMBL273412)
Show SMILES COc1cccc2CCC3C(CCN3CC=C)c12
Show InChI InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3
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4.70n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50455997
PNG
(CHEMBL10048)
Show SMILES Oc1cccc2CCC3C(CCN3CC=C)c12
Show InChI InChI=1S/C15H19NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h2-5,12-13,17H,1,6-10H2
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4.90n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50455993
PNG
(CHEMBL273412)
Show SMILES COc1cccc2CCC3C(CCN3CC=C)c12
Show InChI InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3
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8.5n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for agonistic activity against D2 receptor from cloned CHO cells, used [3H]U-86170 as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50455999
PNG
(CHEMBL2114337)
Show SMILES CCCN1CCC2Cc3c(O)cccc3CC12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3
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11n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for agonistic activity against D2 receptor from cloned CHO cells, used [3H]U-86170 as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50455993
PNG
(CHEMBL273412)
Show SMILES COc1cccc2CCC3C(CCN3CC=C)c12
Show InChI InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3
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13n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50455997
PNG
(CHEMBL10048)
Show SMILES Oc1cccc2CCC3C(CCN3CC=C)c12
Show InChI InChI=1S/C15H19NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h2-5,12-13,17H,1,6-10H2
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25n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011251
PNG
(4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quin...)
Show SMILES CCCN1CCC[C@H]2[C@H]1CCc1cccc(O)c21
Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-14(17)9-8-12-5-3-7-15(18)16(12)13/h3,5,7,13-14,18H,2,4,6,8-11H2,1H3/t13-,14+/m0/s1
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32n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50455996
PNG
(CHEMBL566133)
Show SMILES Oc1cccc2[C@H]3CCN(CC=C)[C@H]3CCc12
Show InChI InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12-,14+/m1/s1
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59n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for agonistic activity against D2 receptor from cloned CHO cells, used [3H]U-86170 as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50455994
PNG
(CHEMBL2051769)
Show SMILES CCCN1CC[C@@H]2[C@@H]1CCc1c(OC)cccc21
Show InChI InChI=1S/C16H23NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m0/s1
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63n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50455994
PNG
(CHEMBL2051769)
Show SMILES CCCN1CC[C@@H]2[C@@H]1CCc1c(OC)cccc21
Show InChI InChI=1S/C16H23NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m0/s1
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66n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011248
PNG
(1-Propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]qui...)
Show SMILES CCCN1CCC[C@H]2Cc3cccc(O)c3C[C@@H]12
Show InChI InChI=1S/C16H23NO/c1-2-8-17-9-4-6-13-10-12-5-3-7-16(18)14(12)11-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m0/s1
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151n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50455996
PNG
(CHEMBL566133)
Show SMILES Oc1cccc2[C@H]3CCN(CC=C)[C@H]3CCc12
Show InChI InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12-,14+/m1/s1
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259n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50455999
PNG
(CHEMBL2114337)
Show SMILES CCCN1CCC2Cc3c(O)cccc3CC12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3
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296n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50455996
PNG
(CHEMBL566133)
Show SMILES Oc1cccc2[C@H]3CCN(CC=C)[C@H]3CCc12
Show InChI InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12-,14+/m1/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50455999
PNG
(CHEMBL2114337)
Show SMILES CCCN1CCC2Cc3c(O)cccc3CC12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3
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>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50455995
PNG
(CHEMBL2051973)
Show SMILES CCCN1CC[C@H]2[C@@H]1CCc1c(OC)cccc21
Show InChI InChI=1S/C16H23NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15+/m1/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50455995
PNG
(CHEMBL2051973)
Show SMILES CCCN1CC[C@H]2[C@@H]1CCc1c(OC)cccc21
Show InChI InChI=1S/C16H23NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15+/m1/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligand


J Med Chem 36: 1301-15 (1993)


Article DOI: 10.1021/jm00062a001
BindingDB Entry DOI: 10.7270/Q2TD9Z06
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011252
PNG
(7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphth...)
Show SMILES CCCN(CCC)[C@H]1CCc2cccc(O)c2[C@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-11-18(12-5-2)15-10-9-14-7-6-8-16(19)17(14)13(15)3/h6-8,13,15,19H,4-5,9-12H2,1-3H3/t13-,15-/m0/s1
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1.04E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011249
PNG
(1-Propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]qui...)
Show SMILES CCCN1CCC[C@@H]2Cc3cccc(O)c3C[C@@H]12
Show InChI InChI=1S/C16H23NO/c1-2-8-17-9-4-6-13-10-12-5-3-7-16(18)14(12)11-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15-/m1/s1
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2.81E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011252
PNG
(7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphth...)
Show SMILES CCCN(CCC)[C@H]1CCc2cccc(O)c2[C@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-11-18(12-5-2)15-10-9-14-7-6-8-16(19)17(14)13(15)3/h6-8,13,15,19H,4-5,9-12H2,1-3H3/t13-,15-/m0/s1
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2.92E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]-8-OH-DPAT as radioligand


J Med Chem 38: 150-60 (1995)


Article DOI: 10.1021/jm00001a020
BindingDB Entry DOI: 10.7270/Q2W09505
More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(Rattus norvegicus (rat))
BDBM50011252
PNG
(7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphth...)
Show SMILES CCCN(CCC)[C@H]1CCc2cccc(O)c2[C@H]1C
Show InChI InChI=1S/C17H27NO/c1-4-11-18(12-5-2)15-10-9-14-7-6-8-16(19)17(14)13(15)3/h6-8,13,15,19H,4-5,9-12H2,1-3H3/t13-,15-/m0/s1
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2.92E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50011253
PNG
(1-Propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]qui...)
Show SMILES CCCN1CCC[C@H]2Cc3cccc(O)c3C[C@H]12
Show InChI InChI=1S/C16H23NO/c1-2-8-17-9-4-6-13-10-12-5-3-7-16(18)14(12)11-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.


J Med Chem 34: 497-510 (1991)


Article DOI: 10.1021/jm00106a004
BindingDB Entry DOI: 10.7270/Q2PK0GRB
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452347
PNG
(CHEMBL306162)
Show SMILES CCCN1CCC[C@@H]2[C@H]1CCc1c(O)cccc21
Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)
BDBM50452347
PNG
(CHEMBL306162)
Show SMILES CCCN1CCC[C@@H]2[C@H]1CCc1c(O)cccc21
Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m0/s1
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n/an/a 197n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452345
PNG
(CHEMBL2114053)
Show SMILES CCCN1CCC[C@H]2[C@@H]1CCc1c(O)cccc21
Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m1/s1
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n/an/a 2.10E+3n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a)


(Rattus norvegicus (rat))
BDBM50452345
PNG
(CHEMBL2114053)
Show SMILES CCCN1CCC[C@H]2[C@@H]1CCc1c(O)cccc21
Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m1/s1
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n/an/a 160n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)
BDBM50452345
PNG
(CHEMBL2114053)
Show SMILES CCCN1CCC[C@H]2[C@@H]1CCc1c(O)cccc21
Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m1/s1
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n/an/a 416n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)
BDBM50452345
PNG
(CHEMBL2114053)
Show SMILES CCCN1CCC[C@H]2[C@@H]1CCc1c(O)cccc21
Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m1/s1
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n/an/a 48n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452344
PNG
(CHEMBL2114055)
Show SMILES Oc1cccc2[C@H]3CCCN[C@@H]3CCc12
Show InChI InChI=1S/C13H17NO/c15-13-5-1-3-9-10-4-2-8-14-12(10)7-6-11(9)13/h1,3,5,10,12,14-15H,2,4,6-8H2/t10-,12-/m1/s1
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n/an/a 1.55E+3n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)
BDBM50452344
PNG
(CHEMBL2114055)
Show SMILES Oc1cccc2[C@H]3CCCN[C@@H]3CCc12
Show InChI InChI=1S/C13H17NO/c15-13-5-1-3-9-10-4-2-8-14-12(10)7-6-11(9)13/h1,3,5,10,12,14-15H,2,4,6-8H2/t10-,12-/m1/s1
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n/an/a 2.37E+3n/an/an/an/an/an/a



University of G£teborg

Curated by ChEMBL


Assay Description
In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand


J Med Chem 30: 2169-74 (1988)


Article DOI: 10.1021/jm00395a002
BindingDB Entry DOI: 10.7270/Q2MW2HQJ
More data for this
Ligand-Target Pair