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1 similar compounds to monomer 50011875

Compile data set for download or QSAR
Wt: 440.6
BDBM50011628

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011628   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50011628
PNG
(4-(2-Chloro-phenyl)-2-iodo-9-methyl-6H-1-thia-5,7,...)
Show SMILES Cc1nnc2CN=C(c3cc(I)sc3-n12)c1ccccc1Cl
Show InChI InChI=1S/C15H10ClIN4S/c1-8-19-20-13-7-18-14(9-4-2-3-5-11(9)16)10-6-12(17)22-15(10)21(8)13/h2-6H,7H2,1H3
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Similars

Article
PubMed
n/an/a 370n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
PAF-antagonist activity determined in dog platelets by PAF-binding assay


J Med Chem 34: 1209-21 (1991)


Article DOI: 10.1021/jm00107a048
BindingDB Entry DOI: 10.7270/Q23X85M1
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50011628
PNG
(4-(2-Chloro-phenyl)-2-iodo-9-methyl-6H-1-thia-5,7,...)
Show SMILES Cc1nnc2CN=C(c3cc(I)sc3-n12)c1ccccc1Cl
Show InChI InChI=1S/C15H10ClIN4S/c1-8-19-20-13-7-18-14(9-4-2-3-5-11(9)16)10-6-12(17)22-15(10)21(8)13/h2-6H,7H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 370n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.


J Med Chem 34: 1440-6 (1991)


Article DOI: 10.1021/jm00108a031
BindingDB Entry DOI: 10.7270/Q2BG2MZ9
More data for this
Ligand-Target Pair