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3 similar compounds to monomer 50405736

Compile data set for download or QSAR
Wt: 429.5
BDBM50020302
Wt: 555.4
BDBM50020303
Wt: 513.3
BDBM50087678

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50020302,50020303,50087678   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukotriene B4 receptor


(Homo sapiens (Human))
BDBM50087678
PNG
(CHEMBL168507 | Sodium; {3-[(E)-7-(4-azido-3-iodo-p...)
Show SMILES OC(CCCCc1ccc(N=[N+]=[N-])c(I)c1)\C=C\C1CCCC(O)(CC(O)=O)C1
Show InChI InChI=1S/C21H28IN3O4/c22-18-12-15(8-10-19(18)24-25-23)4-1-2-6-17(26)9-7-16-5-3-11-21(29,13-16)14-20(27)28/h7-10,12,16-17,26,29H,1-6,11,13-14H2,(H,27,28)/b9-7+
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n/an/a>1.00E+4n/an/an/an/an/an/a



UPRESA-CNRS 5074

Curated by ChEMBL


Assay Description
Compound was tested for inhibition against binding of radioligand [3H]-LTB4 to Leukotriene B4 receptor in human neutrophil membranes


Bioorg Med Chem Lett 10: 811-4 (2000)


Article DOI: 10.1016/s0960-894x(00)00103-7
BindingDB Entry DOI: 10.7270/Q2W37VHF
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50020302
PNG
((S-isomer)7-{2-[5-(4-Azido-phenyl)-3-hydroxy-pent-...)
Show SMILES O[C@@H](CCc1ccc(cc1)N=[N+]=[N-])\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C23H31N3O5/c24-26-25-17-10-7-16(8-11-17)9-12-18(27)13-14-20-19(21(28)15-22(20)29)5-3-1-2-4-6-23(30)31/h1,3,7-8,10-11,13-14,18-22,27-29H,2,4-6,9,12,15H2,(H,30,31)/b3-1-,14-13+/t18-,19+,20+,21-,22+/m0/s1
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n/an/a 330n/an/an/an/an/an/a



University of Kentucky

Curated by ChEMBL


Assay Description
Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in ovine luteal cells (OLC)


J Med Chem 32: 256-64 (1989)


Article DOI: 10.1021/jm00121a046
BindingDB Entry DOI: 10.7270/Q23F4Q7C
More data for this
Ligand-Target Pair
PTGFR


(BOVINE)
BDBM50020302
PNG
((S-isomer)7-{2-[5-(4-Azido-phenyl)-3-hydroxy-pent-...)
Show SMILES O[C@@H](CCc1ccc(cc1)N=[N+]=[N-])\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C23H31N3O5/c24-26-25-17-10-7-16(8-11-17)9-12-18(27)13-14-20-19(21(28)15-22(20)29)5-3-1-2-4-6-23(30)31/h1,3,7-8,10-11,13-14,18-22,27-29H,2,4-6,9,12,15H2,(H,30,31)/b3-1-,14-13+/t18-,19+,20+,21-,22+/m0/s1
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n/an/a 7.00E+3n/an/an/an/an/an/a



University of Kentucky

Curated by ChEMBL


Assay Description
Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes...


J Med Chem 32: 256-64 (1989)


Article DOI: 10.1021/jm00121a046
BindingDB Entry DOI: 10.7270/Q23F4Q7C
More data for this
Ligand-Target Pair
PTGFR


(BOVINE)
BDBM50020303
PNG
((R-isomer)7-{2-[5-(4-Azido-3-iodo-phenyl)-3-hydrox...)
Show SMILES O[C@@H](CCc1ccc(N=[N+]=[N-])c(I)c1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C23H30IN3O5/c24-19-13-15(8-12-20(19)26-27-25)7-9-16(28)10-11-18-17(21(29)14-22(18)30)5-3-1-2-4-6-23(31)32/h1,3,8,10-13,16-18,21-22,28-30H,2,4-7,9,14H2,(H,31,32)/b3-1-,11-10+/t16-,17+,18+,21-,22+/m0/s1
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n/an/a 7.00E+3n/an/an/an/an/an/a



University of Kentucky

Curated by ChEMBL


Assay Description
Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes...


J Med Chem 32: 256-64 (1989)


Article DOI: 10.1021/jm00121a046
BindingDB Entry DOI: 10.7270/Q23F4Q7C
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50020303
PNG
((R-isomer)7-{2-[5-(4-Azido-3-iodo-phenyl)-3-hydrox...)
Show SMILES O[C@@H](CCc1ccc(N=[N+]=[N-])c(I)c1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C23H30IN3O5/c24-19-13-15(8-12-20(19)26-27-25)7-9-16(28)10-11-18-17(21(29)14-22(18)30)5-3-1-2-4-6-23(31)32/h1,3,8,10-13,16-18,21-22,28-30H,2,4-7,9,14H2,(H,31,32)/b3-1-,11-10+/t16-,17+,18+,21-,22+/m0/s1
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n/an/a 350n/an/an/an/an/an/a



University of Kentucky

Curated by ChEMBL


Assay Description
Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in ovine luteal cells (OLC)


J Med Chem 32: 256-64 (1989)


Article DOI: 10.1021/jm00121a046
BindingDB Entry DOI: 10.7270/Q23F4Q7C
More data for this
Ligand-Target Pair