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5 similar compounds to monomer 50218116

Compile data set for download or QSAR
Wt: 318.4
BDBM50030525
Wt: 382.4
BDBM50218119
Wt: 340.4
BDBM50218120
Wt: 402.4
BDBM50218122
Wt: 354.4
BDBM50218123

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50030525,50218119,50218120,50218122,50218123   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50030525
PNG
(1-Benzyl-4-hexyloxy-naphthalene | CHEMBL56808)
Show SMILES CCCCCCOc1ccc(Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C23H26O/c1-2-3-4-10-17-24-23-16-15-20(18-19-11-6-5-7-12-19)21-13-8-9-14-22(21)23/h5-9,11-16H,2-4,10,17-18H2,1H3
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n/an/a>5.00E+3n/an/an/an/an/an/a



Sanofi Winthrop Inc.

Curated by ChEMBL


Assay Description
Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.


J Med Chem 38: 1877-83 (1995)


Article DOI: 10.1021/jm00011a007
BindingDB Entry DOI: 10.7270/Q2GQ6WSJ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50218119
PNG
((4-hexyloxynaphthalen-1-yl)naphthalen-1-ylmethanon...)
Show SMILES CCCCCCOc1ccc(C(=O)c2cccc3ccccc23)c2ccccc12
Show InChI InChI=1S/C27H26O2/c1-2-3-4-9-19-29-26-18-17-25(22-14-7-8-15-23(22)26)27(28)24-16-10-12-20-11-5-6-13-21(20)24/h5-8,10-18H,2-4,9,19H2,1H3
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n/an/a 160n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cells


J Med Chem 50: 3851-6 (2007)


Article DOI: 10.1021/jm070317a
BindingDB Entry DOI: 10.7270/Q2K64JWR
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50218119
PNG
((4-hexyloxynaphthalen-1-yl)naphthalen-1-ylmethanon...)
Show SMILES CCCCCCOc1ccc(C(=O)c2cccc3ccccc23)c2ccccc12
Show InChI InChI=1S/C27H26O2/c1-2-3-4-9-19-29-26-18-17-25(22-14-7-8-15-23(22)26)27(28)24-16-10-12-20-11-5-6-13-21(20)24/h5-8,10-18H,2-4,9,19H2,1H3
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n/an/a 660n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cells


J Med Chem 50: 3851-6 (2007)


Article DOI: 10.1021/jm070317a
BindingDB Entry DOI: 10.7270/Q2K64JWR
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50218120
PNG
(CHEMBL243334 | naphthalen-1-yl-(4-propoxynaphthale...)
Show SMILES CCCOc1ccc(C(=O)c2cccc3ccccc23)c2ccccc12
Show InChI InChI=1S/C24H20O2/c1-2-16-26-23-15-14-22(19-11-5-6-12-20(19)23)24(25)21-13-7-9-17-8-3-4-10-18(17)21/h3-15H,2,16H2,1H3
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n/an/a 300n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cells


J Med Chem 50: 3851-6 (2007)


Article DOI: 10.1021/jm070317a
BindingDB Entry DOI: 10.7270/Q2K64JWR
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50218123
PNG
(CHEMBL244402 | naphthalen-1-yl-(4-butoxynaphthalen...)
Show SMILES CCCCOc1ccc(C(=O)c2cccc3ccccc23)c2ccccc12
Show InChI InChI=1S/C25H22O2/c1-2-3-17-27-24-16-15-23(20-12-6-7-13-21(20)24)25(26)22-14-8-10-18-9-4-5-11-19(18)22/h4-16H,2-3,17H2,1H3
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n/an/a 48n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cells


J Med Chem 50: 3851-6 (2007)


Article DOI: 10.1021/jm070317a
BindingDB Entry DOI: 10.7270/Q2K64JWR
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50218122
PNG
(CHEMBL244607 | naphthalen-1-yl-(4-phenethyloxynaph...)
Show SMILES O=C(c1cccc2ccccc12)c1ccc(OCCc2ccccc2)c2ccccc12
Show InChI InChI=1S/C29H22O2/c30-29(26-16-8-12-22-11-4-5-13-23(22)26)27-17-18-28(25-15-7-6-14-24(25)27)31-20-19-21-9-2-1-3-10-21/h1-18H,19-20H2
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n/an/a 930n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cells


J Med Chem 50: 3851-6 (2007)


Article DOI: 10.1021/jm070317a
BindingDB Entry DOI: 10.7270/Q2K64JWR
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50218123
PNG
(CHEMBL244402 | naphthalen-1-yl-(4-butoxynaphthalen...)
Show SMILES CCCCOc1ccc(C(=O)c2cccc3ccccc23)c2ccccc12
Show InChI InChI=1S/C25H22O2/c1-2-3-17-27-24-16-15-23(20-12-6-7-13-21(20)24)25(26)22-14-8-10-18-9-4-5-11-19(18)22/h4-16H,2-3,17H2,1H3
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n/an/a 85n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cells


J Med Chem 50: 3851-6 (2007)


Article DOI: 10.1021/jm070317a
BindingDB Entry DOI: 10.7270/Q2K64JWR
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50218122
PNG
(CHEMBL244607 | naphthalen-1-yl-(4-phenethyloxynaph...)
Show SMILES O=C(c1cccc2ccccc12)c1ccc(OCCc2ccccc2)c2ccccc12
Show InChI InChI=1S/C29H22O2/c30-29(26-16-8-12-22-11-4-5-13-23(22)26)27-17-18-28(25-15-7-6-14-24(25)27)31-20-19-21-9-2-1-3-10-21/h1-18H,19-20H2
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n/an/a 2.00E+3n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cells


J Med Chem 50: 3851-6 (2007)


Article DOI: 10.1021/jm070317a
BindingDB Entry DOI: 10.7270/Q2K64JWR
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50218120
PNG
(CHEMBL243334 | naphthalen-1-yl-(4-propoxynaphthale...)
Show SMILES CCCOc1ccc(C(=O)c2cccc3ccccc23)c2ccccc12
Show InChI InChI=1S/C24H20O2/c1-2-16-26-23-15-14-22(19-11-5-6-12-20(19)23)24(25)21-13-7-9-17-8-3-4-10-18(17)21/h3-15H,2,16H2,1H3
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n/an/a 90n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cells


J Med Chem 50: 3851-6 (2007)


Article DOI: 10.1021/jm070317a
BindingDB Entry DOI: 10.7270/Q2K64JWR
More data for this
Ligand-Target Pair