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50 similar compounds to monomer 50096600

Compile data set for download or QSAR
Wt: 414.4
BDBM50030962
Wt: 410.3
BDBM50030963
Wt: 414.4
BDBM50030966
Wt: 400.3
BDBM50030947
Wt: 446.4
BDBM50030948
Wt: 404.8
BDBM50030952
Wt: 421.4
BDBM50030960
Wt: 370.3
BDBM50037777
Wt: 490.5
BDBM50068142
Wt: 402.3
BDBM50068143
Wt: 418.3
BDBM50068145
Wt: 504.5
BDBM50068147
Wt: 416.3
BDBM50068148
Wt: 416.3
BDBM50068149
Wt: 386.3
BDBM50068150
Displayed 1 to 15 (of 50 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 41 hits for monomerid = 50030962,50030963,50030966,50030947,50030948,50030952,50030960,50037777,50068142,50068143,50068145,50068147,50068148,50068149,50068150   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030947
PNG
(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)ncnc12
Show InChI InChI=1S/C18H20N6O5/c1-28-10-4-2-3-9(5-10)17(27)23-12-14(26)11(6-25)29-18(12)24-8-22-13-15(19)20-7-21-16(13)24/h2-5,7-8,11-12,14,18,25-26H,6H2,1H3,(H,23,27)(H2,19,20,21)
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n/an/a 300n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Leishmania mexicana


J Med Chem 37: 3605-13 (1994)


Article DOI: 10.1021/jm00047a017
BindingDB Entry DOI: 10.7270/Q26W9BQD
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50068147
PNG
(CHEMBL356360 | N-{4-Hydroxy-5-hydroxymethyl-2-[6-(...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(NCc3ccccc3C)ncnc12
Show InChI InChI=1S/C26H28N6O5/c1-15-6-3-4-7-17(15)11-27-23-21-24(29-13-28-23)32(14-30-21)26-20(22(34)19(12-33)37-26)31-25(35)16-8-5-9-18(10-16)36-2/h3-10,13-14,19-20,22,26,33-34H,11-12H2,1-2H3,(H,31,35)(H,27,28,29)
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n/an/a 3.00E+4n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity was measured for Glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma brucei


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50037777
PNG
(CHEMBL120653 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1NC(=O)c1ccccc1
Show InChI InChI=1S/C17H18N6O4/c18-14-12-15(20-7-19-14)23(8-21-12)17-11(13(25)10(6-24)27-17)22-16(26)9-4-2-1-3-5-9/h1-5,7-8,10-11,13,17,24-25H,6H2,(H,22,26)(H2,18,19,20)
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n/an/a 6.00E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Trypanosoma brucei


J Med Chem 37: 3605-13 (1994)


Article DOI: 10.1021/jm00047a017
BindingDB Entry DOI: 10.7270/Q26W9BQD
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030947
PNG
(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)ncnc12
Show InChI InChI=1S/C18H20N6O5/c1-28-10-4-2-3-9(5-10)17(27)23-12-14(26)11(6-25)29-18(12)24-8-22-13-15(19)20-7-21-16(13)24/h2-5,7-8,11-12,14,18,25-26H,6H2,1H3,(H,23,27)(H2,19,20,21)
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n/an/a 2.20E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Trypanosoma brucei


J Med Chem 37: 3605-13 (1994)


Article DOI: 10.1021/jm00047a017
BindingDB Entry DOI: 10.7270/Q26W9BQD
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030966
PNG
(CHEMBL125025 | N-[2-(6-Amino-2-methyl-purin-9-yl)-...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)nc(C)nc12
Show InChI InChI=1S/C19H22N6O5/c1-9-22-16(20)14-17(23-9)25(8-21-14)19-13(15(27)12(7-26)30-19)24-18(28)10-4-3-5-11(6-10)29-2/h3-6,8,12-13,15,19,26-27H,7H2,1-2H3,(H,24,28)(H2,20,22,23)
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n/an/a>1.00E+7n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
TInhibition of glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicana


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030948
PNG
(Biphenyl-4-carboxylic acid [2-(6-amino-purin-9-yl)...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C23H22N6O4/c24-20-18-21(26-11-25-20)29(12-27-18)23-17(19(31)16(10-30)33-23)28-22(32)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-9,11-12,16-17,19,23,30-31H,10H2,(H,28,32)(H2,24,25,26)
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n/an/a 4.00E+5n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of Glyceraldehyde-3-phosphate dehydrogenase in human erythrocytes.


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030963
PNG
(1H-Benzoimidazole-5-carboxylic acid [2-(6-amino-pu...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1ccc2nc[nH]c2c1
Show InChI InChI=1S/C18H18N8O4/c19-15-13-16(23-6-22-15)26(7-24-13)18-12(14(28)11(4-27)30-18)25-17(29)8-1-2-9-10(3-8)21-5-20-9/h1-3,5-7,11-12,14,18,27-28H,4H2,(H,20,21)(H,25,29)(H2,19,22,23)
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n/an/a 3.00E+6n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma brucei


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030966
PNG
(CHEMBL125025 | N-[2-(6-Amino-2-methyl-purin-9-yl)-...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)nc(C)nc12
Show InChI InChI=1S/C19H22N6O5/c1-9-22-16(20)14-17(23-9)25(8-21-14)19-13(15(27)12(7-26)30-19)24-18(28)10-4-3-5-11(6-10)29-2/h3-6,8,12-13,15,19,26-27H,7H2,1-2H3,(H,24,28)(H2,20,22,23)
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n/an/a>1.00E+7n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of Glyceraldehyde-3-phosphate dehydrogenase in human erythrocytes.


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030963
PNG
(1H-Benzoimidazole-5-carboxylic acid [2-(6-amino-pu...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1ccc2nc[nH]c2c1
Show InChI InChI=1S/C18H18N8O4/c19-15-13-16(23-6-22-15)26(7-24-13)18-12(14(28)11(4-27)30-18)25-17(29)8-1-2-9-10(3-8)21-5-20-9/h1-3,5-7,11-12,14,18,27-28H,4H2,(H,20,21)(H,25,29)(H2,19,22,23)
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n/an/a>1.00E+7n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of Glyceraldehyde-3-phosphate dehydrogenase in human erythrocytes.


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030947
PNG
(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)ncnc12
Show InChI InChI=1S/C18H20N6O5/c1-28-10-4-2-3-9(5-10)17(27)23-12-14(26)11(6-25)29-18(12)24-8-22-13-15(19)20-7-21-16(13)24/h2-5,7-8,11-12,14,18,25-26H,6H2,1H3,(H,23,27)(H2,19,20,21)
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n/an/a 2.20E+6n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma brucei


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030952
PNG
(CHEMBL125844 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C17H17ClN6O4/c18-9-3-1-2-8(4-9)16(27)23-11-13(26)10(5-25)28-17(11)24-7-22-12-14(19)20-6-21-15(12)24/h1-4,6-7,10-11,13,17,25-26H,5H2,(H,23,27)(H2,19,20,21)
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n/an/a 5.00E+5n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma brucei


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030947
PNG
(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)ncnc12
Show InChI InChI=1S/C18H20N6O5/c1-28-10-4-2-3-9(5-10)17(27)23-12-14(26)11(6-25)29-18(12)24-8-22-13-15(19)20-7-21-16(13)24/h2-5,7-8,11-12,14,18,25-26H,6H2,1H3,(H,23,27)(H2,19,20,21)
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n/an/a>1.00E+7n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of Glyceraldehyde-3-phosphate dehydrogenase in human erythrocytes.


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030962
PNG
(CHEMBL125685 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES CCOc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)ncnc12
Show InChI InChI=1S/C19H22N6O5/c1-2-29-11-5-3-4-10(6-11)18(28)24-13-15(27)12(7-26)30-19(13)25-9-23-14-16(20)21-8-22-17(14)25/h3-6,8-9,12-13,15,19,26-27H,2,7H2,1H3,(H,24,28)(H2,20,21,22)
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n/an/a 4.00E+5n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
TInhibition of glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicana


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030960
PNG
(CHEMBL124621 | Quinoline-7-carboxylic acid [2-(6-a...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1ccc2cccnc2c1
Show InChI InChI=1S/C20H19N7O4/c21-17-15-18(24-8-23-17)27(9-25-15)20-14(16(29)13(7-28)31-20)26-19(30)11-4-3-10-2-1-5-22-12(10)6-11/h1-6,8-9,13-14,16,20,28-29H,7H2,(H,26,30)(H2,21,23,24)
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n/an/a 1.00E+6n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma brucei


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030948
PNG
(Biphenyl-4-carboxylic acid [2-(6-amino-purin-9-yl)...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C23H22N6O4/c24-20-18-21(26-11-25-20)29(12-27-18)23-17(19(31)16(10-30)33-23)28-22(32)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-9,11-12,16-17,19,23,30-31H,10H2,(H,28,32)(H2,24,25,26)
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n/an/a 2.00E+5n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
TInhibition of glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicana


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030952
PNG
(CHEMBL125844 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C17H17ClN6O4/c18-9-3-1-2-8(4-9)16(27)23-11-13(26)10(5-25)28-17(11)24-7-22-12-14(19)20-6-21-15(12)24/h1-4,6-7,10-11,13,17,25-26H,5H2,(H,23,27)(H2,19,20,21)
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n/an/a 2.00E+5n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
TInhibition of glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicana


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030960
PNG
(CHEMBL124621 | Quinoline-7-carboxylic acid [2-(6-a...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1ccc2cccnc2c1
Show InChI InChI=1S/C20H19N7O4/c21-17-15-18(24-8-23-17)27(9-25-15)20-14(16(29)13(7-28)31-20)26-19(30)11-4-3-10-2-1-5-22-12(10)6-11/h1-6,8-9,13-14,16,20,28-29H,7H2,(H,26,30)(H2,21,23,24)
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n/an/a 5.00E+5n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
TInhibition of glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicana


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030962
PNG
(CHEMBL125685 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES CCOc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)ncnc12
Show InChI InChI=1S/C19H22N6O5/c1-2-29-11-5-3-4-10(6-11)18(28)24-13-15(27)12(7-26)30-19(13)25-9-23-14-16(20)21-8-22-17(14)25/h3-6,8-9,12-13,15,19,26-27H,2,7H2,1H3,(H,24,28)(H2,20,21,22)
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n/an/a 5.00E+5n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma brucei


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50068142
PNG
(CHEMBL345010 | N-[2-(6-Benzylamino-purin-9-yl)-4-h...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(NCc3ccccc3)ncnc12
Show InChI InChI=1S/C25H26N6O5/c1-35-17-9-5-8-16(10-17)24(34)30-19-21(33)18(12-32)36-25(19)31-14-29-20-22(27-13-28-23(20)31)26-11-15-6-3-2-4-7-15/h2-10,13-14,18-19,21,25,32-33H,11-12H2,1H3,(H,30,34)(H,26,27,28)
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n/an/a 1.60E+4n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity measured for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in Leishmania. mexicana


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50068142
PNG
(CHEMBL345010 | N-[2-(6-Benzylamino-purin-9-yl)-4-h...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(NCc3ccccc3)ncnc12
Show InChI InChI=1S/C25H26N6O5/c1-35-17-9-5-8-16(10-17)24(34)30-19-21(33)18(12-32)36-25(19)31-14-29-20-22(27-13-28-23(20)31)26-11-15-6-3-2-4-7-15/h2-10,13-14,18-19,21,25,32-33H,11-12H2,1H3,(H,30,34)(H,26,27,28)
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n/an/a 1.59E+5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity was measured for Glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma cruzi.


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50068142
PNG
(CHEMBL345010 | N-[2-(6-Benzylamino-purin-9-yl)-4-h...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(NCc3ccccc3)ncnc12
Show InChI InChI=1S/C25H26N6O5/c1-35-17-9-5-8-16(10-17)24(34)30-19-21(33)18(12-32)36-25(19)31-14-29-20-22(27-13-28-23(20)31)26-11-15-6-3-2-4-7-15/h2-10,13-14,18-19,21,25,32-33H,11-12H2,1H3,(H,30,34)(H,26,27,28)
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n/an/a 2.20E+5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity was measured for Glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma brucei


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50068147
PNG
(CHEMBL356360 | N-{4-Hydroxy-5-hydroxymethyl-2-[6-(...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(NCc3ccccc3C)ncnc12
Show InChI InChI=1S/C26H28N6O5/c1-15-6-3-4-7-17(15)11-27-23-21-24(29-13-28-23)32(14-30-21)26-20(22(34)19(12-33)37-26)31-25(35)16-8-5-9-18(10-16)36-2/h3-10,13-14,19-20,22,26,33-34H,11-12H2,1-2H3,(H,31,35)(H,27,28,29)
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n/an/a>2.70E+5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity was measured for Glyceraldehyde-3-phosphate dehydrogenase in human(erythrocytes)


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50068147
PNG
(CHEMBL356360 | N-{4-Hydroxy-5-hydroxymethyl-2-[6-(...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(NCc3ccccc3C)ncnc12
Show InChI InChI=1S/C26H28N6O5/c1-15-6-3-4-7-17(15)11-27-23-21-24(29-13-28-23)32(14-30-21)26-20(22(34)19(12-33)37-26)31-25(35)16-8-5-9-18(10-16)36-2/h3-10,13-14,19-20,22,26,33-34H,11-12H2,1-2H3,(H,31,35)(H,27,28,29)
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n/an/a 4.00E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity measured for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in Leishmania. mexicana


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50068147
PNG
(CHEMBL356360 | N-{4-Hydroxy-5-hydroxymethyl-2-[6-(...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(NCc3ccccc3C)ncnc12
Show InChI InChI=1S/C26H28N6O5/c1-15-6-3-4-7-17(15)11-27-23-21-24(29-13-28-23)32(14-30-21)26-20(22(34)19(12-33)37-26)31-25(35)16-8-5-9-18(10-16)36-2/h3-10,13-14,19-20,22,26,33-34H,11-12H2,1-2H3,(H,31,35)(H,27,28,29)
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n/an/a 3.00E+4n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity was measured for Glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma cruzi.


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030947
PNG
(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)ncnc12
Show InChI InChI=1S/C18H20N6O5/c1-28-10-4-2-3-9(5-10)17(27)23-12-14(26)11(6-25)29-18(12)24-8-22-13-15(19)20-7-21-16(13)24/h2-5,7-8,11-12,14,18,25-26H,6H2,1H3,(H,23,27)(H2,19,20,21)
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n/an/a 3.00E+5n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
TInhibition of glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicana


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030952
PNG
(CHEMBL125844 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C17H17ClN6O4/c18-9-3-1-2-8(4-9)16(27)23-11-13(26)10(5-25)28-17(11)24-7-22-12-14(19)20-6-21-15(12)24/h1-4,6-7,10-11,13,17,25-26H,5H2,(H,23,27)(H2,19,20,21)
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n/an/a>2.00E+6n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of Glyceraldehyde-3-phosphate dehydrogenase in human erythrocytes.


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030960
PNG
(CHEMBL124621 | Quinoline-7-carboxylic acid [2-(6-a...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1ccc2cccnc2c1
Show InChI InChI=1S/C20H19N7O4/c21-17-15-18(24-8-23-17)27(9-25-15)20-14(16(29)13(7-28)31-20)26-19(30)11-4-3-10-2-1-5-22-12(10)6-11/h1-6,8-9,13-14,16,20,28-29H,7H2,(H,26,30)(H2,21,23,24)
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n/an/a>2.00E+6n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of Glyceraldehyde-3-phosphate dehydrogenase in human erythrocytes.


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030962
PNG
(CHEMBL125685 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES CCOc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)ncnc12
Show InChI InChI=1S/C19H22N6O5/c1-2-29-11-5-3-4-10(6-11)18(28)24-13-15(27)12(7-26)30-19(13)25-9-23-14-16(20)21-8-22-17(14)25/h3-6,8-9,12-13,15,19,26-27H,2,7H2,1H3,(H,24,28)(H2,20,21,22)
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n/an/a 6.00E+5n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of Glyceraldehyde-3-phosphate dehydrogenase in human erythrocytes.


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030963
PNG
(1H-Benzoimidazole-5-carboxylic acid [2-(6-amino-pu...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1ccc2nc[nH]c2c1
Show InChI InChI=1S/C18H18N8O4/c19-15-13-16(23-6-22-15)26(7-24-13)18-12(14(28)11(4-27)30-18)25-17(29)8-1-2-9-10(3-8)21-5-20-9/h1-3,5-7,11-12,14,18,27-28H,4H2,(H,20,21)(H,25,29)(H2,19,22,23)
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n/an/a 3.00E+6n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
TInhibition of glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicana


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030948
PNG
(Biphenyl-4-carboxylic acid [2-(6-amino-purin-9-yl)...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C23H22N6O4/c24-20-18-21(26-11-25-20)29(12-27-18)23-17(19(31)16(10-30)33-23)28-22(32)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-9,11-12,16-17,19,23,30-31H,10H2,(H,28,32)(H2,24,25,26)
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n/an/a 2.00E+5n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma brucei


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030966
PNG
(CHEMBL125025 | N-[2-(6-Amino-2-methyl-purin-9-yl)-...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)nc(C)nc12
Show InChI InChI=1S/C19H22N6O5/c1-9-22-16(20)14-17(23-9)25(8-21-14)19-13(15(27)12(7-26)30-19)24-18(28)10-4-3-5-11(6-10)29-2/h3-6,8,12-13,15,19,26-27H,7H2,1-2H3,(H,24,28)(H2,20,22,23)
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n/an/a>1.00E+7n/an/an/an/an/an/a



University of Ghent

Curated by ChEMBL


Assay Description
Inhibition of glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma brucei


J Med Chem 38: 3838-49 (1995)


Article DOI: 10.1021/jm00019a014
BindingDB Entry DOI: 10.7270/Q2HT2PZ4
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50037777
PNG
(CHEMBL120653 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1NC(=O)c1ccccc1
Show InChI InChI=1S/C17H18N6O4/c18-14-12-15(20-7-19-14)23(8-21-12)17-11(13(25)10(6-24)27-17)22-16(26)9-4-2-1-3-5-9/h1-5,7-8,10-11,13,17,24-25H,6H2,(H,22,26)(H2,18,19,20)
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n/an/a 3.30E+3n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Leishmania mexicana


J Med Chem 37: 3605-13 (1994)


Article DOI: 10.1021/jm00047a017
BindingDB Entry DOI: 10.7270/Q26W9BQD
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030947
PNG
(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)ncnc12
Show InChI InChI=1S/C18H20N6O5/c1-28-10-4-2-3-9(5-10)17(27)23-12-14(26)11(6-25)29-18(12)24-8-22-13-15(19)20-7-21-16(13)24/h2-5,7-8,11-12,14,18,25-26H,6H2,1H3,(H,23,27)(H2,19,20,21)
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyte


J Med Chem 37: 3605-13 (1994)


Article DOI: 10.1021/jm00047a017
BindingDB Entry DOI: 10.7270/Q26W9BQD
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50068143
PNG
(CHEMBL145324 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H18N6O6/c18-14-12-15(20-5-19-14)23(6-21-12)17-11(13(27)10(4-24)29-17)22-16(28)7-1-8(25)3-9(26)2-7/h1-3,5-6,10-11,13,17,24-27H,4H2,(H,22,28)(H2,18,19,20)
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n/an/a 6.50E+5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity measured for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in Leishmania. mexicana


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50030947
PNG
(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)ncnc12
Show InChI InChI=1S/C18H20N6O5/c1-28-10-4-2-3-9(5-10)17(27)23-12-14(26)11(6-25)29-18(12)24-8-22-13-15(19)20-7-21-16(13)24/h2-5,7-8,11-12,14,18,25-26H,6H2,1H3,(H,23,27)(H2,19,20,21)
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n/an/a 8.00E+5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity measured for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in Leishmania. mexicana


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50068145
PNG
(CHEMBL358760 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1cc(O)c(O)c(O)c1
Show InChI InChI=1S/C17H18N6O7/c18-14-11-15(20-4-19-14)23(5-21-11)17-10(13(28)9(3-24)30-17)22-16(29)6-1-7(25)12(27)8(26)2-6/h1-2,4-5,9-10,13,17,24-28H,3H2,(H,22,29)(H2,18,19,20)
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n/an/a 2.50E+5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity measured for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in Leishmania. mexicana


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50068148
PNG
(CHEMBL145415 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES COc1cccc(C(=O)NC2C(O)C(CO)OC2n2cnc3c(N)ncnc23)c1O
Show InChI InChI=1S/C18H20N6O6/c1-29-9-4-2-3-8(13(9)26)17(28)23-11-14(27)10(5-25)30-18(11)24-7-22-12-15(19)20-6-21-16(12)24/h2-4,6-7,10-11,14,18,25-27H,5H2,1H3,(H,23,28)(H2,19,20,21)
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n/an/a 6.00E+5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity measured for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in Leishmania. mexicana


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50068149
PNG
(CHEMBL344302 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES COc1cc(ccc1O)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)ncnc12
Show InChI InChI=1S/C18H20N6O6/c1-29-10-4-8(2-3-9(10)26)17(28)23-12-14(27)11(5-25)30-18(12)24-7-22-13-15(19)20-6-21-16(13)24/h2-4,6-7,11-12,14,18,25-27H,5H2,1H3,(H,23,28)(H2,19,20,21)
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n/an/a 5.00E+5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity measured for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in Leishmania. mexicana


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50068150
PNG
(CHEMBL145212 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1cccc(O)c1
Show InChI InChI=1S/C17H18N6O5/c18-14-12-15(20-6-19-14)23(7-21-12)17-11(13(26)10(5-24)28-17)22-16(27)8-2-1-3-9(25)4-8/h1-4,6-7,10-11,13,17,24-26H,5H2,(H,22,27)(H2,18,19,20)
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n/an/a 8.50E+5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity measured for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in Leishmania. mexicana


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50068142
PNG
(CHEMBL345010 | N-[2-(6-Benzylamino-purin-9-yl)-4-h...)
Show SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(NCc3ccccc3)ncnc12
Show InChI InChI=1S/C25H26N6O5/c1-35-17-9-5-8-16(10-17)24(34)30-19-21(33)18(12-32)36-25(19)31-14-29-20-22(27-13-28-23(20)31)26-11-15-6-3-2-4-7-15/h2-10,13-14,18-19,21,25,32-33H,11-12H2,1H3,(H,30,34)(H,26,27,28)
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n/an/a>5.30E+5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibitory activity was measured for Glyceraldehyde-3-phosphate dehydrogenase in human(erythrocytes)


J Med Chem 41: 4790-9 (1998)


Article DOI: 10.1021/jm9802620
BindingDB Entry DOI: 10.7270/Q2Q240ZW
More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens (Human))
BDBM50037777
PNG
(CHEMBL120653 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1NC(=O)c1ccccc1
Show InChI InChI=1S/C17H18N6O4/c18-14-12-15(20-7-19-14)23(8-21-12)17-11(13(25)10(6-24)27-17)22-16(26)9-4-2-1-3-5-9/h1-5,7-8,10-11,13,17,24-25H,6H2,(H,22,26)(H2,18,19,20)
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyte


J Med Chem 37: 3605-13 (1994)


Article DOI: 10.1021/jm00047a017
BindingDB Entry DOI: 10.7270/Q26W9BQD
More data for this
Ligand-Target Pair