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15 similar compounds to monomer 50037272

Compile data set for download or QSAR
Wt: 270.4
BDBM50035307
Wt: 270.4
BDBM50035329
Wt: 270.4
BDBM50035330
Wt: 242.3
BDBM50035340
Wt: 268.3
BDBM50035357
Wt: 240.3
BDBM50035365
Wt: 228.3
BDBM50035348
Wt: 332.4
BDBM50035351
Wt: 282.4
BDBM50035355
Wt: 448.6
BDBM50368633
Wt: 295.4
BDBM50368635
Wt: 313.4
BDBM50368637
Wt: 313.4
BDBM50368639
Wt: 448.6
BDBM50368641
Wt: 284.4
BDBM50369018

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 81 hits for monomerid = 50035307,50035329,50035330,50035340,50035357,50035365,50035348,50035351,50035355,50368633,50368635,50368637,50368639,50368641,50369018   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50368641
PNG
(CHEMBL1744088)
Show SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)[C@@H]1CCc2ccc3[nH]c(cc3c2C1)C#N
Show InChI InChI=1S/C27H36N4O2/c1-4-11-30(12-5-6-13-31-25(32)16-27(2,3)17-26(31)33)21-9-7-19-8-10-24-23(22(19)15-21)14-20(18-28)29-24/h8,10,14,21,29H,4-7,9,11-13,15-17H2,1-3H3/t21-/m1/s1
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0.200n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of bovine hippocampus.


J Med Chem 36: 2066-74 (1993)


Article DOI: 10.1021/jm00067a003
BindingDB Entry DOI: 10.7270/Q2HX1D9Z
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50368635
PNG
(CHEMBL1744035)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]c(cc3c2C1)C#N
Show InChI InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-19-18(17(14)12-16)11-15(13-20)21-19/h6,8,11,16,21H,3-5,7,9-10,12H2,1-2H3/t16-/m0/s1
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0.400n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of bovine hippocampus.


J Med Chem 36: 2066-74 (1993)


Article DOI: 10.1021/jm00067a003
BindingDB Entry DOI: 10.7270/Q2HX1D9Z
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035351
PNG
(CHEMBL72285 | Phenethyl-propyl-(6,7,8,9-tetrahydro...)
Show SMILES CCCN(CCc1ccccc1)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C23H28N2/c1-2-15-25(16-13-18-6-4-3-5-7-18)20-10-8-19-9-11-23-21(12-14-24-23)22(19)17-20/h3-7,9,11-12,14,20,24H,2,8,10,13,15-17H2,1H3
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0.700n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035365
PNG
(8-Pyrrolidin-1-yl-6,7,8,9-tetrahydro-3H-benzo[e]in...)
Show SMILES C1CCN(C1)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C16H20N2/c1-2-10-18(9-1)13-5-3-12-4-6-16-14(7-8-17-16)15(12)11-13/h4,6-8,13,17H,1-3,5,9-11H2
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0.800n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035307
PNG
(CHEMBL302171 | Dipropyl-(S)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1
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1.40n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035307
PNG
(CHEMBL302171 | Dipropyl-(S)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1
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1.40n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor from CHO-K1 cells, using [3H]-8-OH-DPAT as the radioligand.


J Med Chem 38: 2202-16 (1995)


Article DOI: 10.1021/jm00012a021
BindingDB Entry DOI: 10.7270/Q24T6HD0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50368637
PNG
(CHEMBL1744036)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]c(cc3c2C1)C(N)=O
Show InChI InChI=1S/C19H27N3O/c1-3-9-22(10-4-2)14-7-5-13-6-8-17-16(15(13)11-14)12-18(21-17)19(20)23/h6,8,12,14,21H,3-5,7,9-11H2,1-2H3,(H2,20,23)/t14-/m1/s1
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1.60n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of bovine hippocampus.


J Med Chem 36: 2066-74 (1993)


Article DOI: 10.1021/jm00067a003
BindingDB Entry DOI: 10.7270/Q2HX1D9Z
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50368639
PNG
(CHEMBL1788190)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]c(cc3c2C1)C(N)=O
Show InChI InChI=1S/C19H27N3O/c1-3-9-22(10-4-2)14-7-5-13-6-8-17-16(15(13)11-14)12-18(21-17)19(20)23/h6,8,12,14,21H,3-5,7,9-11H2,1-2H3,(H2,20,23)/t14-/m0/s1
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1.90n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of bovine hippocampus.


J Med Chem 36: 2066-74 (1993)


Article DOI: 10.1021/jm00067a003
BindingDB Entry DOI: 10.7270/Q2HX1D9Z
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035355
PNG
(CHEMBL69729 | Cyclopropylmethyl-propyl-(6,7,8,9-te...)
Show SMILES CCCN(CC1CC1)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C19H26N2/c1-2-11-21(13-14-3-4-14)16-7-5-15-6-8-19-17(9-10-20-19)18(15)12-16/h6,8-10,14,16,20H,2-5,7,11-13H2,1H3
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2.5n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50368633
PNG
(CHEMBL1788324)
Show SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)[C@H]1CCc2ccc3[nH]c(cc3c2C1)C#N
Show InChI InChI=1S/C27H36N4O2/c1-4-11-30(12-5-6-13-31-25(32)16-27(2,3)17-26(31)33)21-9-7-19-8-10-24-23(22(19)15-21)14-20(18-28)29-24/h8,10,14,21,29H,4-7,9,11-13,15-17H2,1-3H3/t21-/m0/s1
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2.80n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of bovine hippocampus.


J Med Chem 36: 2066-74 (1993)


Article DOI: 10.1021/jm00067a003
BindingDB Entry DOI: 10.7270/Q2HX1D9Z
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035348
PNG
(CHEMBL305976 | Propyl-(6,7,8,9-tetrahydro-3H-benzo...)
Show SMILES CCCNC1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C15H20N2/c1-2-8-16-12-5-3-11-4-6-15-13(7-9-17-15)14(11)10-12/h4,6-7,9,12,16-17H,2-3,5,8,10H2,1H3
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3.20n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035329
PNG
((+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3
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3.30n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035329
PNG
((+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3
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3.30n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor from CHO-K1 cells, using [3H]-8-OH-DPAT as the radioligand.


J Med Chem 38: 2202-16 (1995)


Article DOI: 10.1021/jm00012a021
BindingDB Entry DOI: 10.7270/Q24T6HD0
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50369018
PNG
(CHEMBL1744041)
Show SMILES CCCN(CC(C)C)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C19H28N2/c1-4-11-21(13-14(2)3)16-7-5-15-6-8-19-17(9-10-20-19)18(15)12-16/h6,8-10,14,16,20H,4-5,7,11-13H2,1-3H3/t16-/m1/s1
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3.60n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035330
PNG
(CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1
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5.20n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035330
PNG
(CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1
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5.20n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor from CHO-K1 cells, using [3H]-8-OH-DPAT as the radioligand.


J Med Chem 38: 2202-16 (1995)


Article DOI: 10.1021/jm00012a021
BindingDB Entry DOI: 10.7270/Q24T6HD0
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50035351
PNG
(CHEMBL72285 | Phenethyl-propyl-(6,7,8,9-tetrahydro...)
Show SMILES CCCN(CCc1ccccc1)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C23H28N2/c1-2-15-25(16-13-18-6-4-3-5-7-18)20-10-8-19-9-11-23-21(12-14-24-23)22(19)17-20/h3-7,9,11-12,14,20,24H,2,8,10,13,15-17H2,1H3
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5.5n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian Dopamine receptor D2 expressed in CHO cells using [3H]U-86170 as radioligand


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50369018
PNG
(CHEMBL1744041)
Show SMILES CCCN(CC(C)C)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C19H28N2/c1-4-11-21(13-14(2)3)16-7-5-15-6-8-19-17(9-10-20-19)18(15)12-16/h6,8-10,14,16,20H,4-5,7,11-13H2,1-3H3/t16-/m1/s1
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5.70n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian Dopamine receptor D2 expressed in CHO cells using [3H]U-86170 as radioligand


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035330
PNG
(CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1
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7n/an/an/an/an/an/an/an/a



University of Göteborg

Curated by ChEMBL


Assay Description
In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT


J Med Chem 36: 2059-65 (1993)


Article DOI: 10.1021/jm00067a002
BindingDB Entry DOI: 10.7270/Q2MP52CR
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035330
PNG
(CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1
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7n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor


J Med Chem 37: 3263-73 (1994)


Article DOI: 10.1021/jm00046a010
BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50035330
PNG
(CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1
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7.40n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity rat Dopamine receptor D2 expressed in CHO-K1 cells by [3H]U-86170 displacement.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50035330
PNG
(CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1
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7.40n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 expressed in CHO-K1 cells, using [3H]-U-86,170 as the radioligand.


J Med Chem 38: 2202-16 (1995)


Article DOI: 10.1021/jm00012a021
BindingDB Entry DOI: 10.7270/Q24T6HD0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))
BDBM50035351
PNG
(CHEMBL72285 | Phenethyl-propyl-(6,7,8,9-tetrahydro...)
Show SMILES CCCN(CCc1ccccc1)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C23H28N2/c1-2-15-25(16-13-18-6-4-3-5-7-18)20-10-8-19-9-11-23-21(12-14-24-23)22(19)17-20/h3-7,9,11-12,14,20,24H,2,8,10,13,15-17H2,1H3
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7.40n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligand


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035329
PNG
((+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3
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12n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor


J Med Chem 37: 3263-73 (1994)


Article DOI: 10.1021/jm00046a010
BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035329
PNG
((+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3
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12n/an/an/an/an/an/an/an/a



University of Göteborg

Curated by ChEMBL


Assay Description
In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT


J Med Chem 36: 2059-65 (1993)


Article DOI: 10.1021/jm00067a002
BindingDB Entry DOI: 10.7270/Q2MP52CR
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035340
PNG
(CHEMBL71409 | Methyl-propyl-(6,7,8,9-tetrahydro-3H...)
Show SMILES CCCN(C)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C16H22N2/c1-3-10-18(2)13-6-4-12-5-7-16-14(8-9-17-16)15(12)11-13/h5,7-9,13,17H,3-4,6,10-11H2,1-2H3
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14n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035307
PNG
(CHEMBL302171 | Dipropyl-(S)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1
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14n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor


J Med Chem 37: 3263-73 (1994)


Article DOI: 10.1021/jm00046a010
BindingDB Entry DOI: 10.7270/Q21R6PJ7
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035307
PNG
(CHEMBL302171 | Dipropyl-(S)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1
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14n/an/an/an/an/an/an/an/a



University of Göteborg

Curated by ChEMBL


Assay Description
In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT


J Med Chem 36: 2059-65 (1993)


Article DOI: 10.1021/jm00067a002
BindingDB Entry DOI: 10.7270/Q2MP52CR
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50035357
PNG
(8-Azepan-1-yl-6,7,8,9-tetrahydro-3H-benzo[e]indole...)
Show SMILES C1Cc2ccc3[nH]ccc3c2CC1N1CCCCCC1
Show InChI InChI=1S/C18H24N2/c1-2-4-12-20(11-3-1)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,1-5,7,11-13H2
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15n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50035329
PNG
((+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3
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15n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity rat Dopamine receptor D2 expressed in CHO-K1 cells by [3H]U-86170 displacement.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50035329
PNG
((+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3
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15n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 expressed in CHO-K1 cells, using [3H]-U-86,170 as the radioligand.


J Med Chem 38: 2202-16 (1995)


Article DOI: 10.1021/jm00012a021
BindingDB Entry DOI: 10.7270/Q24T6HD0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))
BDBM50035330
PNG
(CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1
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16n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1D receptor alpha expressed in CHO-K1 cells, using [3H]-5-HT as the radioligand.


J Med Chem 38: 2202-16 (1995)


Article DOI: 10.1021/jm00012a021
BindingDB Entry DOI: 10.7270/Q24T6HD0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))
BDBM50035330
PNG
(CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1
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16n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligand


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50035307
PNG
(CHEMBL302171 | Dipropyl-(S)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1
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17n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 expressed in CHO-K1 cells, using [3H]-U-86,170 as the radioligand.


J Med Chem 38: 2202-16 (1995)


Article DOI: 10.1021/jm00012a021
BindingDB Entry DOI: 10.7270/Q24T6HD0
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50035307
PNG
(CHEMBL302171 | Dipropyl-(S)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1
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17n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity rat Dopamine receptor D2 expressed in CHO-K1 cells by [3H]U-86170 displacement.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50035351
PNG
(CHEMBL72285 | Phenethyl-propyl-(6,7,8,9-tetrahydro...)
Show SMILES CCCN(CCc1ccccc1)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C23H28N2/c1-2-15-25(16-13-18-6-4-3-5-7-18)20-10-8-19-9-11-23-21(12-14-24-23)22(19)17-20/h3-7,9,11-12,14,20,24H,2,8,10,13,15-17H2,1H3
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18n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian Dopamine receptor D3 expressed in CHO cells by, using [3H]-spiperone as radioligand


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50369018
PNG
(CHEMBL1744041)
Show SMILES CCCN(CC(C)C)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C19H28N2/c1-4-11-21(13-14(2)3)16-7-5-15-6-8-19-17(9-10-20-19)18(15)12-16/h6,8-10,14,16,20H,4-5,7,11-13H2,1-3H3/t16-/m1/s1
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18n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian Dopamine receptor D3 expressed in CHO cells by, using [3H]-spiperone as radioligand


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50035307
PNG
(CHEMBL302171 | Dipropyl-(S)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1
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22n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian Dopamine receptor D3 expressed in CHO cells by, using [3H]-spiperone as radioligand


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50035307
PNG
(CHEMBL302171 | Dipropyl-(S)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1
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22n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D3 expressed in CHO-K1 cells, using [3H]-spiperone as the radioligand.


J Med Chem 38: 2202-16 (1995)


Article DOI: 10.1021/jm00012a021
BindingDB Entry DOI: 10.7270/Q24T6HD0
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50035330
PNG
(CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1
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30n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian Dopamine receptor D3 expressed in CHO cells by, using [3H]-spiperone as radioligand


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50035330
PNG
(CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1
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30n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D3 expressed in CHO-K1 cells, using [3H]-spiperone as the radioligand.


J Med Chem 38: 2202-16 (1995)


Article DOI: 10.1021/jm00012a021
BindingDB Entry DOI: 10.7270/Q24T6HD0
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50035340
PNG
(CHEMBL71409 | Methyl-propyl-(6,7,8,9-tetrahydro-3H...)
Show SMILES CCCN(C)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C16H22N2/c1-3-10-18(2)13-6-4-12-5-7-16-14(8-9-17-16)15(12)11-13/h5,7-9,13,17H,3-4,6,10-11H2,1-2H3
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33n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity rat Dopamine receptor D2 expressed in CHO-K1 cells by [3H]U-86170 displacement.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50035355
PNG
(CHEMBL69729 | Cyclopropylmethyl-propyl-(6,7,8,9-te...)
Show SMILES CCCN(CC1CC1)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C19H26N2/c1-2-11-21(13-14-3-4-14)16-7-5-15-6-8-19-17(9-10-20-19)18(15)12-16/h6,8-10,14,16,20H,2-5,7,11-13H2,1H3
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33n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity rat Dopamine receptor D2 expressed in CHO-K1 cells by [3H]U-86170 displacement.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))
BDBM50369018
PNG
(CHEMBL1744041)
Show SMILES CCCN(CC(C)C)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C19H28N2/c1-4-11-21(13-14(2)3)16-7-5-15-6-8-19-17(9-10-20-19)18(15)12-16/h6,8-10,14,16,20H,4-5,7,11-13H2,1-3H3/t16-/m1/s1
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35n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligand


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50035329
PNG
((+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3
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37n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D3 expressed in CHO-K1 cells, using [3H]-spiperone as the radioligand.


J Med Chem 38: 2202-16 (1995)


Article DOI: 10.1021/jm00012a021
BindingDB Entry DOI: 10.7270/Q24T6HD0
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50035329
PNG
((+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3
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37n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian Dopamine receptor D3 expressed in CHO cells by, using [3H]-spiperone as radioligand


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))
BDBM50035329
PNG
((+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3
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39n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligand


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))
BDBM50035329
PNG
((+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Show SMILES CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3
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40n/an/an/an/an/an/an/an/a



Göteborg University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1D receptor alpha expressed in CHO-K1 cells, using [3H]-5-HT as the radioligand.


J Med Chem 38: 2202-16 (1995)


Article DOI: 10.1021/jm00012a021
BindingDB Entry DOI: 10.7270/Q24T6HD0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50368641
PNG
(CHEMBL1744088)
Show SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)[C@@H]1CCc2ccc3[nH]c(cc3c2C1)C#N
Show InChI InChI=1S/C27H36N4O2/c1-4-11-30(12-5-6-13-31-25(32)16-27(2,3)17-26(31)33)21-9-7-19-8-10-24-23(22(19)15-21)14-20(18-28)29-24/h8,10,14,21,29H,4-7,9,11-13,15-17H2,1-3H3/t21-/m1/s1
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44n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]U-86170 from human D2-dopamine receptor expressed in CHO K1 cells


J Med Chem 36: 2066-74 (1993)


Article DOI: 10.1021/jm00067a003
BindingDB Entry DOI: 10.7270/Q2HX1D9Z
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50035348
PNG
(CHEMBL305976 | Propyl-(6,7,8,9-tetrahydro-3H-benzo...)
Show SMILES CCCNC1CCc2ccc3[nH]ccc3c2C1
Show InChI InChI=1S/C15H20N2/c1-2-8-16-12-5-3-11-4-6-15-13(7-9-17-15)14(11)10-12/h4,6-7,9,12,16-17H,2-3,5,8,10H2,1H3
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48n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity rat Dopamine receptor D2 expressed in CHO-K1 cells by [3H]U-86170 displacement.


J Med Chem 38: 2217-30 (1995)


Article DOI: 10.1021/jm00012a022
BindingDB Entry DOI: 10.7270/Q28G8MBW
More data for this
Ligand-Target Pair
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