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36 similar compounds to monomer 50180777

Compile data set for download or QSAR
Wt: 1160.1
BDBM50368764
Wt: 813.8
BDBM50368762
Wt: 960.9
BDBM50368745
Wt: 1196.3
BDBM50062162
Wt: 1163.2
BDBM50062163
Wt: 1178.2
BDBM50062164
Wt: 1196.3
BDBM50062170
Wt: 1165.2
BDBM50062171
Wt: 1193.3
BDBM50062174
Wt: 1184.3
BDBM50062176
Wt: 1167.2
BDBM50062183
Wt: 1167.2
BDBM50062185
Wt: 1199.2
BDBM50062189
Wt: 1209.3
BDBM50062193
Wt: 1091.1
BDBM50062194
Displayed 1 to 15 (of 36 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50368764,50368762,50368745,50062162,50062163,50062164,50062170,50062171,50062174,50062176,50062183,50062185,50062189,50062193,50062194   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1


(Homo sapiens (Human))
BDBM50062162
PNG
(CHEMBL264010 | FVPTDVGPFAF)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C60H81N11O15/c1-33(2)48(67-54(79)42(31-47(74)75)65-58(83)50(36(6)72)69-56(81)45-25-17-27-71(45)59(84)49(34(3)4)68-52(77)40(61)28-37-18-10-7-11-19-37)57(82)62-32-46(73)70-26-16-24-44(70)55(80)64-41(29-38-20-12-8-13-21-38)53(78)63-35(5)51(76)66-43(60(85)86)30-39-22-14-9-15-23-39/h7-15,18-23,33-36,40-45,48-50,72H,16-17,24-32,61H2,1-6H3,(H,62,82)(H,63,78)(H,64,80)(H,65,83)(H,66,76)(H,67,79)(H,68,77)(H,69,81)(H,74,75)(H,85,86)/t35-,36+,40-,41-,42-,43-,44-,45-,48-,49-,50-/m0/s1
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0.0200n/an/an/an/an/an/an/an/a



University of Leipzig

Curated by ChEMBL


Assay Description
Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cells


J Med Chem 49: 616-24 (2006)


Article DOI: 10.1021/jm050613s
BindingDB Entry DOI: 10.7270/Q280526H
More data for this
Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1


(Homo sapiens (Human))
BDBM50062162
PNG
(CHEMBL264010 | FVPTDVGPFAF)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C60H81N11O15/c1-33(2)48(67-54(79)42(31-47(74)75)65-58(83)50(36(6)72)69-56(81)45-25-17-27-71(45)59(84)49(34(3)4)68-52(77)40(61)28-37-18-10-7-11-19-37)57(82)62-32-46(73)70-26-16-24-44(70)55(80)64-41(29-38-20-12-8-13-21-38)53(78)63-35(5)51(76)66-43(60(85)86)30-39-22-14-9-15-23-39/h7-15,18-23,33-36,40-45,48-50,72H,16-17,24-32,61H2,1-6H3,(H,62,82)(H,63,78)(H,64,80)(H,65,83)(H,66,76)(H,67,79)(H,68,77)(H,69,81)(H,74,75)(H,85,86)/t35-,36+,40-,41-,42-,43-,44-,45-,48-,49-,50-/m0/s1
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14n/an/an/an/an/an/an/an/a



University of Leipzig

Curated by ChEMBL


Assay Description
Displacement of [125I-Tyr10] from halphaCGRP expressed in human neuroblastoma SK-N-MC cells


J Med Chem 49: 616-24 (2006)


Article DOI: 10.1021/jm050613s
BindingDB Entry DOI: 10.7270/Q280526H
More data for this
Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))
BDBM50062162
PNG
(CHEMBL264010 | FVPTDVGPFAF)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C60H81N11O15/c1-33(2)48(67-54(79)42(31-47(74)75)65-58(83)50(36(6)72)69-56(81)45-25-17-27-71(45)59(84)49(34(3)4)68-52(77)40(61)28-37-18-10-7-11-19-37)57(82)62-32-46(73)70-26-16-24-44(70)55(80)64-41(29-38-20-12-8-13-21-38)53(78)63-35(5)51(76)66-43(60(85)86)30-39-22-14-9-15-23-39/h7-15,18-23,33-36,40-45,48-50,72H,16-17,24-32,61H2,1-6H3,(H,62,82)(H,63,78)(H,64,80)(H,65,83)(H,66,76)(H,67,79)(H,68,77)(H,69,81)(H,74,75)(H,85,86)/t35-,36+,40-,41-,42-,43-,44-,45-,48-,49-,50-/m0/s1
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n/an/a 29n/an/an/an/an/an/a



ETH Zürich

Curated by ChEMBL


Assay Description
CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.


J Med Chem 41: 117-23 (1998)


Article DOI: 10.1021/jm970533r
BindingDB Entry DOI: 10.7270/Q2736Q0S
More data for this
Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))
BDBM50062193
PNG
(Ac-FVPTNVGSEAF | CHEMBL262749)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(C)C)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C56H80N12O18/c1-28(2)44(53(82)58-26-42(73)61-39(27-69)51(80)62-35(20-21-43(74)75)48(77)59-30(5)47(76)64-38(56(85)86)24-34-17-12-9-13-18-34)65-50(79)37(25-41(57)72)63-54(83)46(31(6)70)67-52(81)40-19-14-22-68(40)55(84)45(29(3)4)66-49(78)36(60-32(7)71)23-33-15-10-8-11-16-33/h8-13,15-18,28-31,35-40,44-46,69-70H,14,19-27H2,1-7H3,(H2,57,72)(H,58,82)(H,59,77)(H,60,71)(H,61,73)(H,62,80)(H,63,83)(H,64,76)(H,65,79)(H,66,78)(H,67,81)(H,74,75)(H,85,86)/t30-,31+,35-,36-,37-,38-,39-,40-,44-,45-,46-/m0/s1
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n/an/a 4.50E+3n/an/an/an/an/an/a



ETH Zürich

Curated by ChEMBL


Assay Description
CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.


J Med Chem 41: 117-23 (1998)


Article DOI: 10.1021/jm970533r
BindingDB Entry DOI: 10.7270/Q2736Q0S
More data for this
Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))
BDBM50062164
PNG
(CHEMBL274851 | FVPTDVGPEAF)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C56H79N11O17/c1-29(2)44(53(80)58-28-41(69)66-23-13-19-39(66)51(78)60-36(21-22-42(70)71)49(76)59-31(5)47(74)62-38(56(83)84)26-34-17-11-8-12-18-34)63-50(77)37(27-43(72)73)61-54(81)46(32(6)68)65-52(79)40-20-14-24-67(40)55(82)45(30(3)4)64-48(75)35(57)25-33-15-9-7-10-16-33/h7-12,15-18,29-32,35-40,44-46,68H,13-14,19-28,57H2,1-6H3,(H,58,80)(H,59,76)(H,60,78)(H,61,81)(H,62,74)(H,63,77)(H,64,75)(H,65,79)(H,70,71)(H,72,73)(H,83,84)/t31-,32+,35-,36-,37-,38-,39-,40-,44-,45-,46-/m0/s1
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n/an/a 470n/an/an/an/an/an/a



ETH Zürich

Curated by ChEMBL


Assay Description
CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.


J Med Chem 41: 117-23 (1998)


Article DOI: 10.1021/jm970533r
BindingDB Entry DOI: 10.7270/Q2736Q0S
More data for this
Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))
BDBM50062174
PNG
(CHEMBL384703 | FVPTNVGSEPF)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C56H80N12O17/c1-29(2)44(52(80)59-27-42(72)60-38(28-69)49(77)61-35(20-21-43(73)74)54(82)67-22-12-18-39(67)50(78)63-37(56(84)85)25-33-16-10-7-11-17-33)64-48(76)36(26-41(58)71)62-53(81)46(31(5)70)66-51(79)40-19-13-23-68(40)55(83)45(30(3)4)65-47(75)34(57)24-32-14-8-6-9-15-32/h6-11,14-17,29-31,34-40,44-46,69-70H,12-13,18-28,57H2,1-5H3,(H2,58,71)(H,59,80)(H,60,72)(H,61,77)(H,62,81)(H,63,78)(H,64,76)(H,65,75)(H,66,79)(H,73,74)(H,84,85)/t31-,34+,35+,36+,37+,38+,39+,40+,44+,45+,46+/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



ETH Zürich

Curated by ChEMBL


Assay Description
CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.


J Med Chem 41: 117-23 (1998)


Article DOI: 10.1021/jm970533r
BindingDB Entry DOI: 10.7270/Q2736Q0S
More data for this
Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))
BDBM50062176
PNG
(CHEMBL411804 | FVPTDVG-Aib-FAF)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)[C@@H](C)O)C(=O)NCC(=O)NC(C)(C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C59H81N11O15/c1-32(2)46(54(80)61-31-44(72)69-59(7,8)58(85)65-40(28-37-21-14-10-15-22-37)51(77)62-34(5)49(75)64-42(57(83)84)29-38-23-16-11-17-24-38)66-52(78)41(30-45(73)74)63-55(81)48(35(6)71)68-53(79)43-25-18-26-70(43)56(82)47(33(3)4)67-50(76)39(60)27-36-19-12-9-13-20-36/h9-17,19-24,32-35,39-43,46-48,71H,18,25-31,60H2,1-8H3,(H,61,80)(H,62,77)(H,63,81)(H,64,75)(H,65,85)(H,66,78)(H,67,76)(H,68,79)(H,69,72)(H,73,74)(H,83,84)/t34-,35+,39-,40-,41-,42-,43-,46-,47-,48-/m0/s1
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n/an/a 170n/an/an/an/an/an/a



ETH Zürich

Curated by ChEMBL


Assay Description
CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.


J Med Chem 41: 117-23 (1998)


Article DOI: 10.1021/jm970533r
BindingDB Entry DOI: 10.7270/Q2736Q0S
More data for this
Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))
BDBM50062163
PNG
(CHEMBL414069 | FVPPNVGSEAF)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C55H78N12O16/c1-29(2)44(52(79)58-27-42(70)60-38(28-68)50(77)61-35(20-21-43(71)72)48(75)59-31(5)46(73)63-37(55(82)83)25-33-16-10-7-11-17-33)64-49(76)36(26-41(57)69)62-51(78)39-18-12-22-66(39)53(80)40-19-13-23-67(40)54(81)45(30(3)4)65-47(74)34(56)24-32-14-8-6-9-15-32/h6-11,14-17,29-31,34-40,44-45,68H,12-13,18-28,56H2,1-5H3,(H2,57,69)(H,58,79)(H,59,75)(H,60,70)(H,61,77)(H,62,78)(H,63,73)(H,64,76)(H,65,74)(H,71,72)(H,82,83)/t31-,34-,35-,36-,37-,38-,39-,40-,44-,45-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



ETH Zürich

Curated by ChEMBL


Assay Description
CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.


J Med Chem 41: 117-23 (1998)


Article DOI: 10.1021/jm970533r
BindingDB Entry DOI: 10.7270/Q2736Q0S
More data for this
Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))
BDBM50062183
PNG
(CHEMBL407740 | FVPTNVGSEAF)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C54H78N12O17/c1-27(2)42(51(79)57-25-40(70)59-37(26-67)49(77)60-34(19-20-41(71)72)47(75)58-29(5)45(73)62-36(54(82)83)23-32-16-11-8-12-17-32)63-48(76)35(24-39(56)69)61-52(80)44(30(6)68)65-50(78)38-18-13-21-66(38)53(81)43(28(3)4)64-46(74)33(55)22-31-14-9-7-10-15-31/h7-12,14-17,27-30,33-38,42-44,67-68H,13,18-26,55H2,1-6H3,(H2,56,69)(H,57,79)(H,58,75)(H,59,70)(H,60,77)(H,61,80)(H,62,73)(H,63,76)(H,64,74)(H,65,78)(H,71,72)(H,82,83)/t29-,30+,33-,34-,35-,36-,37-,38-,42-,43-,44-/m0/s1
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n/an/a 3.00E+3n/an/an/an/an/an/a



ETH Zürich

Curated by ChEMBL


Assay Description
CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.


J Med Chem 41: 117-23 (1998)


Article DOI: 10.1021/jm970533r
BindingDB Entry DOI: 10.7270/Q2736Q0S
More data for this
Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))
BDBM50062189
PNG
(CHEMBL407697 | YVHyp-TNVGSEAF)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C54H78N12O19/c1-25(2)42(51(81)57-22-40(72)59-37(24-67)49(79)60-34(16-17-41(73)74)47(77)58-27(5)45(75)62-36(54(84)85)19-29-10-8-7-9-11-29)63-48(78)35(21-39(56)71)61-52(82)44(28(6)68)65-50(80)38-20-32(70)23-66(38)53(83)43(26(3)4)64-46(76)33(55)18-30-12-14-31(69)15-13-30/h7-15,25-28,32-38,42-44,67-70H,16-24,55H2,1-6H3,(H2,56,71)(H,57,81)(H,58,77)(H,59,72)(H,60,79)(H,61,82)(H,62,75)(H,63,78)(H,64,76)(H,65,80)(H,73,74)(H,84,85)/t27-,28+,32+,33-,34-,35-,36-,37-,38-,42-,43-,44-/m0/s1
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n/an/a 9.00E+3n/an/an/an/an/an/a



ETH Zürich

Curated by ChEMBL


Assay Description
CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.


J Med Chem 41: 117-23 (1998)


Article DOI: 10.1021/jm970533r
BindingDB Entry DOI: 10.7270/Q2736Q0S
More data for this
Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))
BDBM50062194
PNG
(AVPTNVGSEAF | CHEMBL404977)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C48H74N12O17/c1-22(2)36(57-42(70)29(19-33(50)63)55-46(74)38(26(7)62)59-44(72)32-14-11-17-60(32)47(75)37(23(3)4)58-39(67)24(5)49)45(73)51-20-34(64)53-31(21-61)43(71)54-28(15-16-35(65)66)41(69)52-25(6)40(68)56-30(48(76)77)18-27-12-9-8-10-13-27/h8-10,12-13,22-26,28-32,36-38,61-62H,11,14-21,49H2,1-7H3,(H2,50,63)(H,51,73)(H,52,69)(H,53,64)(H,54,71)(H,55,74)(H,56,68)(H,57,70)(H,58,67)(H,59,72)(H,65,66)(H,76,77)/t24-,25-,26+,28-,29-,30-,31-,32-,36-,37-,38-/m0/s1
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n/an/a 2.40E+4n/an/an/an/an/an/a



ETH Zürich

Curated by ChEMBL


Assay Description
CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.


J Med Chem 41: 117-23 (1998)


Article DOI: 10.1021/jm970533r
BindingDB Entry DOI: 10.7270/Q2736Q0S
More data for this
Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))
BDBM50062171
PNG
(CHEMBL408025 | FVPTNPGSEAF)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C54H76N12O17/c1-28(2)43(63-46(74)33(55)23-31-13-7-5-8-14-31)53(81)66-22-12-18-39(66)50(78)64-44(30(4)68)51(79)61-35(25-40(56)69)52(80)65-21-11-17-38(65)49(77)57-26-41(70)59-37(27-67)48(76)60-34(19-20-42(71)72)47(75)58-29(3)45(73)62-36(54(82)83)24-32-15-9-6-10-16-32/h5-10,13-16,28-30,33-39,43-44,67-68H,11-12,17-27,55H2,1-4H3,(H2,56,69)(H,57,77)(H,58,75)(H,59,70)(H,60,76)(H,61,79)(H,62,73)(H,63,74)(H,64,78)(H,71,72)(H,82,83)/t29-,30+,33-,34-,35-,36-,37-,38-,39-,43-,44-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



ETH Zürich

Curated by ChEMBL


Assay Description
CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.


J Med Chem 41: 117-23 (1998)


Article DOI: 10.1021/jm970533r
BindingDB Entry DOI: 10.7270/Q2736Q0S
More data for this
Ligand-Target Pair
Ribonucleoside-diphosphate reductase M1 chain


(Mus musculus)
BDBM50368762
PNG
(CHEMBL2369634)
Show SMILES C[C@@H](O)[C@H](NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C37H47N7O14/c1-19(45)31(39-20(2)46)36(56)43-24(15-21-9-5-3-6-10-21)33(53)41-25(17-28(38)47)34(54)40-23(13-14-29(48)49)32(52)42-26(18-30(50)51)35(55)44-27(37(57)58)16-22-11-7-4-8-12-22/h3-12,19,23-27,31,45H,13-18H2,1-2H3,(H2,38,47)(H,39,46)(H,40,54)(H,41,53)(H,42,52)(H,43,56)(H,44,55)(H,48,49)(H,50,51)(H,57,58)/t19-,23+,24+,25+,26+,27+,31+/m1/s1
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n/an/a 6.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Cross inhibitory potency of compound on Saccharomyces cerevisiae R2 C-terminal peptide on mammalian ribonucleotide reductase


J Med Chem 36: 3859-62 (1994)


Article DOI: 10.1021/jm00076a015
BindingDB Entry DOI: 10.7270/Q2V40VTV
More data for this
Ligand-Target Pair
Ribonucleoside-diphosphate reductase M1 chain


(Mus musculus)
BDBM50368745
PNG
(CHEMBL2369633)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C46H56N8O15/c1-25(55)39(54-44(66)31(48-26(2)56)20-27-12-6-3-7-13-27)45(67)52-32(21-28-14-8-4-9-15-28)41(63)50-33(23-36(47)57)42(64)49-30(18-19-37(58)59)40(62)51-34(24-38(60)61)43(65)53-35(46(68)69)22-29-16-10-5-11-17-29/h3-17,25,30-35,39,55H,18-24H2,1-2H3,(H2,47,57)(H,48,56)(H,49,64)(H,50,63)(H,51,62)(H,52,67)(H,53,65)(H,54,66)(H,58,59)(H,60,61)(H,68,69)/t25-,30+,31+,32+,33+,34+,35+,39+/m1/s1
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n/an/a 2.50E+4n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Cross inhibitory potency of compound on Saccharomyces cerevisiae R2 C-terminal peptide on Saccharomyces cerevisiae ribonucleotide reductase


J Med Chem 36: 3859-62 (1994)


Article DOI: 10.1021/jm00076a015
BindingDB Entry DOI: 10.7270/Q2V40VTV
More data for this
Ligand-Target Pair
Ribonucleoside-diphosphate reductase M1 chain


(Mus musculus)
BDBM50368764
PNG
(CHEMBL2369635)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](C)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C54H69N11O18/c1-28(57-31(4)67)46(74)56-27-42(69)58-29(2)47(75)60-37(23-33-16-10-6-11-17-33)52(80)65-45(30(3)66)53(81)63-36(22-32-14-8-5-9-15-32)49(77)61-38(25-41(55)68)50(78)59-35(20-21-43(70)71)48(76)62-39(26-44(72)73)51(79)64-40(54(82)83)24-34-18-12-7-13-19-34/h5-19,28-30,35-40,45,66H,20-27H2,1-4H3,(H2,55,68)(H,56,74)(H,57,67)(H,58,69)(H,59,78)(H,60,75)(H,61,77)(H,62,76)(H,63,81)(H,64,79)(H,65,80)(H,70,71)(H,72,73)(H,82,83)/t28-,29-,30+,35-,36-,37-,38-,39-,40-,45-/m0/s1
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n/an/a 2.50E+4n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Cross inhibitory potency of compound on Saccharomyces cerevisiae R2 C-terminal peptide on Saccharomyces cerevisiae ribonucleotide reductase


J Med Chem 36: 3859-62 (1994)


Article DOI: 10.1021/jm00076a015
BindingDB Entry DOI: 10.7270/Q2V40VTV
More data for this
Ligand-Target Pair
Ribonucleoside-diphosphate reductase M1 chain


(Mus musculus)
BDBM50368745
PNG
(CHEMBL2369633)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C46H56N8O15/c1-25(55)39(54-44(66)31(48-26(2)56)20-27-12-6-3-7-13-27)45(67)52-32(21-28-14-8-4-9-15-28)41(63)50-33(23-36(47)57)42(64)49-30(18-19-37(58)59)40(62)51-34(24-38(60)61)43(65)53-35(46(68)69)22-29-16-10-5-11-17-29/h3-17,25,30-35,39,55H,18-24H2,1-2H3,(H2,47,57)(H,48,56)(H,49,64)(H,50,63)(H,51,62)(H,52,67)(H,53,65)(H,54,66)(H,58,59)(H,60,61)(H,68,69)/t25-,30+,31+,32+,33+,34+,35+,39+/m1/s1
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n/an/a 1.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Cross inhibitory potency of compound on Saccharomyces cerevisiae R2 C-terminal peptide on mammalian ribonucleotide reductase


J Med Chem 36: 3859-62 (1994)


Article DOI: 10.1021/jm00076a015
BindingDB Entry DOI: 10.7270/Q2V40VTV
More data for this
Ligand-Target Pair
Ribonucleoside-diphosphate reductase M1 chain


(Mus musculus)
BDBM50368762
PNG
(CHEMBL2369634)
Show SMILES C[C@@H](O)[C@H](NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C37H47N7O14/c1-19(45)31(39-20(2)46)36(56)43-24(15-21-9-5-3-6-10-21)33(53)41-25(17-28(38)47)34(54)40-23(13-14-29(48)49)32(52)42-26(18-30(50)51)35(55)44-27(37(57)58)16-22-11-7-4-8-12-22/h3-12,19,23-27,31,45H,13-18H2,1-2H3,(H2,38,47)(H,39,46)(H,40,54)(H,41,53)(H,42,52)(H,43,56)(H,44,55)(H,48,49)(H,50,51)(H,57,58)/t19-,23+,24+,25+,26+,27+,31+/m1/s1
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n/an/a 6.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Cross inhibitory potency of compound on Saccharomyces cerevisiae R2 C-terminal peptide on mammalian ribonucleotide reductase


J Med Chem 36: 3859-62 (1994)


Article DOI: 10.1021/jm00076a015
BindingDB Entry DOI: 10.7270/Q2V40VTV
More data for this
Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))
BDBM50062170
PNG
(CHEMBL428655 | FVPTDVG-Acp-FAF)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)[C@@H](C)O)C(=O)NCC(=O)NCC1CC1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C60H81N11O15/c1-32(2)48(68-55(80)43(29-47(74)75)66-58(83)50(35(6)72)70-56(81)45-23-16-24-71(45)59(84)49(33(3)4)69-53(78)41(61)25-36-17-10-7-11-18-36)57(82)63-31-46(73)62-30-39-28-40(39)52(77)65-42(26-37-19-12-8-13-20-37)54(79)64-34(5)51(76)67-44(60(85)86)27-38-21-14-9-15-22-38/h7-15,17-22,32-35,39-45,48-50,72H,16,23-31,61H2,1-6H3,(H,62,73)(H,63,82)(H,64,79)(H,65,77)(H,66,83)(H,67,76)(H,68,80)(H,69,78)(H,70,81)(H,74,75)(H,85,86)/t34-,35+,39?,40?,41-,42-,43-,44-,45-,48-,49-,50-/m0/s1
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n/an/a>3.00E+3n/an/an/an/an/an/a



ETH Zürich

Curated by ChEMBL


Assay Description
CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.


J Med Chem 41: 117-23 (1998)


Article DOI: 10.1021/jm970533r
BindingDB Entry DOI: 10.7270/Q2736Q0S
More data for this
Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))
BDBM50062185
PNG
(CHEMBL216710 | FVPTDVGSQAF)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C54H78N12O17/c1-27(2)42(51(79)57-25-40(70)59-37(26-67)49(77)60-34(19-20-39(56)69)47(75)58-29(5)45(73)62-36(54(82)83)23-32-16-11-8-12-17-32)63-48(76)35(24-41(71)72)61-52(80)44(30(6)68)65-50(78)38-18-13-21-66(38)53(81)43(28(3)4)64-46(74)33(55)22-31-14-9-7-10-15-31/h7-12,14-17,27-30,33-38,42-44,67-68H,13,18-26,55H2,1-6H3,(H2,56,69)(H,57,79)(H,58,75)(H,59,70)(H,60,77)(H,61,80)(H,62,73)(H,63,76)(H,64,74)(H,65,78)(H,71,72)(H,82,83)/t29-,30+,33-,34-,35-,36-,37-,38-,42-,43-,44-/m0/s1
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n/an/a 1.20E+3n/an/an/an/an/an/a



ETH Zürich

Curated by ChEMBL


Assay Description
CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.


J Med Chem 41: 117-23 (1998)


Article DOI: 10.1021/jm970533r
BindingDB Entry DOI: 10.7270/Q2736Q0S
More data for this
Ligand-Target Pair