BindingDB logo
myBDB logout

4 similar compounds to monomer 50369784

Compile data set for download or QSAR
Wt: 295.4
BDBM50066541
Wt: 309.4
BDBM50085921
Wt: 309.4
BDBM50369790
Wt: 309.4
BDBM50369791

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50066541,50085921,50369790,50369791   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50066541
PNG
(4-[2-(4-Benzyl-piperidin-1-yl)-ethyl]-phenol; hydr...)
Show SMILES Oc1ccc(CCN2CCC(Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C20H25NO/c22-20-8-6-17(7-9-20)10-13-21-14-11-19(12-15-21)16-18-4-2-1-3-5-18/h1-9,19,22H,10-16H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Oregon

Curated by ChEMBL


Assay Description
Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2C NMDA receptor


J Med Chem 41: 3499-506 (1998)


Article DOI: 10.1021/jm980235+
BindingDB Entry DOI: 10.7270/Q29Z95MM
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50066541
PNG
(4-[2-(4-Benzyl-piperidin-1-yl)-ethyl]-phenol; hydr...)
Show SMILES Oc1ccc(CCN2CCC(Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C20H25NO/c22-20-8-6-17(7-9-20)10-13-21-14-11-19(12-15-21)16-18-4-2-1-3-5-18/h1-9,19,22H,10-16H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



University of Oregon

Curated by ChEMBL


Assay Description
Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2B NMDA receptor


J Med Chem 41: 3499-506 (1998)


Article DOI: 10.1021/jm980235+
BindingDB Entry DOI: 10.7270/Q29Z95MM
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50066541
PNG
(4-[2-(4-Benzyl-piperidin-1-yl)-ethyl]-phenol; hydr...)
Show SMILES Oc1ccc(CCN2CCC(Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C20H25NO/c22-20-8-6-17(7-9-20)10-13-21-14-11-19(12-15-21)16-18-4-2-1-3-5-18/h1-9,19,22H,10-16H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.70E+4n/an/an/an/an/an/a



University of Oregon

Curated by ChEMBL


Assay Description
Functional antagonism by electrical assays in Xenopus oocytes expressing 1A/2A NMDA receptor subtype


J Med Chem 41: 3499-506 (1998)


Article DOI: 10.1021/jm980235+
BindingDB Entry DOI: 10.7270/Q29Z95MM
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085921
PNG
(4-[1-(3-Phenyl-propyl)-piperidin-4-ylmethyl]-pheno...)
Show SMILES Oc1ccc(CC2CCN(CCCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C21H27NO/c23-21-10-8-19(9-11-21)17-20-12-15-22(16-13-20)14-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-11,20,23H,4,7,12-17H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085921
PNG
(4-[1-(3-Phenyl-propyl)-piperidin-4-ylmethyl]-pheno...)
Show SMILES Oc1ccc(CC2CCN(CCCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C21H27NO/c23-21-10-8-19(9-11-21)17-20-12-15-22(16-13-20)14-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-11,20,23H,4,7,12-17H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 59n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50369790
PNG
(CHEMBL1203914)
Show SMILES Oc1ccc(CCCCN2CCC(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C21H27NO/c23-21-11-9-18(10-12-21)6-4-5-15-22-16-13-20(14-17-22)19-7-2-1-3-8-19/h1-3,7-12,20,23H,4-6,13-17H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369790
PNG
(CHEMBL1203914)
Show SMILES Oc1ccc(CCCCN2CCC(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C21H27NO/c23-21-11-9-18(10-12-21)6-4-5-15-22-16-13-20(14-17-22)19-7-2-1-3-8-19/h1-3,7-12,20,23H,4-6,13-17H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.30E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50369791
PNG
(CHEMBL1202296)
Show SMILES Oc1ccc(cc1)C1CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C21H27NO/c23-21-11-9-19(10-12-21)20-13-16-22(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20,23H,4-5,8,13-17H2
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-raclopride binding at Dopamine receptor D2 in rat brain membranes.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369791
PNG
(CHEMBL1202296)
Show SMILES Oc1ccc(cc1)C1CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C21H27NO/c23-21-11-9-19(10-12-21)20-13-16-22(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20,23H,4-5,8,13-17H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 22n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369791
PNG
(CHEMBL1202296)
Show SMILES Oc1ccc(cc1)C1CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C21H27NO/c23-21-11-9-19(10-12-21)20-13-16-22(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20,23H,4-5,8,13-17H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369790
PNG
(CHEMBL1203914)
Show SMILES Oc1ccc(CCCCN2CCC(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C21H27NO/c23-21-11-9-18(10-12-21)6-4-5-15-22-16-13-20(14-17-22)19-7-2-1-3-8-19/h1-3,7-12,20,23H,4-6,13-17H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 230n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50369791
PNG
(CHEMBL1202296)
Show SMILES Oc1ccc(cc1)C1CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C21H27NO/c23-21-11-9-19(10-12-21)20-13-16-22(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20,23H,4-5,8,13-17H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50085921
PNG
(4-[1-(3-Phenyl-propyl)-piperidin-4-ylmethyl]-pheno...)
Show SMILES Oc1ccc(CC2CCN(CCCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C21H27NO/c23-21-10-8-19(9-11-21)17-20-12-15-22(16-13-20)14-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-11,20,23H,4,7,12-17H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair