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50 similar compounds to monomer 50376852

Compile data set for download or QSAR
Wt: 365.4
BDBM50067668
Wt: 399.9
BDBM50067669
Wt: 383.4
BDBM50067670
Wt: 401.4
BDBM50067671
Wt: 399.9
BDBM50067672
Wt: 395.4
BDBM50067673
Wt: 444.3
BDBM50067675
Wt: 401.4
BDBM50067676
Wt: 379.4
BDBM50067677
Wt: 401.4
BDBM50067680
Wt: 399.9
BDBM50067681
Wt: 383.4
BDBM50067682
Wt: 379.4
BDBM50067683
Wt: 379.4
BDBM50067684
Wt: 401.4
BDBM50067685
Displayed 1 to 15 (of 50 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 56 hits for monomerid = 50067668,50067669,50067670,50067671,50067672,50067673,50067675,50067676,50067677,50067680,50067681,50067682,50067683,50067684,50067685   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))
BDBM50067684
PNG
(2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4C)c3c12
Show InChI InChI=1S/C27H25NO/c1-17-9-5-6-10-19(17)15-24-26-21(20-11-7-8-12-23(20)29-24)13-14-22-25(26)18(2)16-27(3,4)28-22/h5-16,28H,1-4H3/b24-15-
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0.660n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human progesterone receptor


Bioorg Med Chem Lett 13: 2071-4 (2003)


Article DOI: 10.1016/s0960-894x(03)00255-5
BindingDB Entry DOI: 10.7270/Q2SX6DSM
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067684
PNG
(2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4C)c3c12
Show InChI InChI=1S/C27H25NO/c1-17-9-5-6-10-19(17)15-24-26-21(20-11-7-8-12-23(20)29-24)13-14-22-25(26)18(2)16-27(3,4)28-22/h5-16,28H,1-4H3/b24-15-
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0.660n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity towards human progesterone receptor A isoform using progesterone as radioligand


J Med Chem 46: 4104-12 (2003)


Article DOI: 10.1021/jm020477g
BindingDB Entry DOI: 10.7270/Q2QZ29C6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067684
PNG
(2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4C)c3c12
Show InChI InChI=1S/C27H25NO/c1-17-9-5-6-10-19(17)15-24-26-21(20-11-7-8-12-23(20)29-24)13-14-22-25(26)18(2)16-27(3,4)28-22/h5-16,28H,1-4H3/b24-15-
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0.660n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067670
PNG
(5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(F)c4)c3c12
Show InChI InChI=1S/C26H22FNO/c1-16-15-26(2,3)28-21-12-11-20-19-9-4-5-10-22(19)29-23(25(20)24(16)21)14-17-7-6-8-18(27)13-17/h4-15,28H,1-3H3/b23-14-
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0.830n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity against baculovirus expressed Progesterone receptor


J Med Chem 42: 1466-72 (1999)


Article DOI: 10.1021/jm980723h
BindingDB Entry DOI: 10.7270/Q2NK3FQ9
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067670
PNG
(5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(F)c4)c3c12
Show InChI InChI=1S/C26H22FNO/c1-16-15-26(2,3)28-21-12-11-20-19-9-4-5-10-22(19)29-23(25(20)24(16)21)14-17-7-6-8-18(27)13-17/h4-15,28H,1-3H3/b23-14-
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0.830n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067669
PNG
(5-[1-(2-Chloro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4Cl)c3c12
Show InChI InChI=1S/C26H22ClNO/c1-16-15-26(2,3)28-21-13-12-19-18-9-5-7-11-22(18)29-23(25(19)24(16)21)14-17-8-4-6-10-20(17)27/h4-15,28H,1-3H3/b23-14-
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1.30n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067671
PNG
(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cc(F)ccc4F)c3c12
Show InChI InChI=1S/C26H21F2NO/c1-15-14-26(2,3)29-21-11-9-19-18-6-4-5-7-22(18)30-23(25(19)24(15)21)13-16-12-17(27)8-10-20(16)28/h4-14,29H,1-3H3/b23-13-
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1.5n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067682
PNG
(5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccc(F)cc4)c3c12
Show InChI InChI=1S/C26H22FNO/c1-16-15-26(2,3)28-21-13-12-20-19-6-4-5-7-22(19)29-23(25(20)24(16)21)14-17-8-10-18(27)11-9-17/h4-15,28H,1-3H3/b23-14-
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3.5n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067668
PNG
(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4)c3c12
Show InChI InChI=1S/C26H23NO/c1-17-16-26(2,3)27-21-14-13-20-19-11-7-8-12-22(19)28-23(25(20)24(17)21)15-18-9-5-4-6-10-18/h4-16,27H,1-3H3/b23-15-
PDB

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4.90n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067681
PNG
(5-[1-(3-Chloro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(Cl)c4)c3c12
Show InChI InChI=1S/C26H22ClNO/c1-16-15-26(2,3)28-21-12-11-20-19-9-4-5-10-22(19)29-23(25(20)24(16)21)14-17-7-6-8-18(27)13-17/h4-15,28H,1-3H3/b23-14-
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18.7n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067675
PNG
(5-[1-(3-Bromo-phenyl)-meth-(Z)-ylidene]-2,2,4-trim...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(Br)c4)c3c12
Show InChI InChI=1S/C26H22BrNO/c1-16-15-26(2,3)28-21-12-11-20-19-9-4-5-10-22(19)29-23(25(20)24(16)21)14-17-7-6-8-18(27)13-17/h4-15,28H,1-3H3/b23-14-
PDB

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22n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067676
PNG
(5-[1-(2,3-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(F)c4F)c3c12
Show InChI InChI=1S/C26H21F2NO/c1-15-14-26(2,3)29-20-12-11-18-17-8-4-5-10-21(17)30-22(24(18)23(15)20)13-16-7-6-9-19(27)25(16)28/h4-14,29H,1-3H3/b22-13-
PDB

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24.3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067685
PNG
(5-[1-(2,6-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4c(F)cccc4F)c3c12
Show InChI InChI=1S/C26H21F2NO/c1-15-14-26(2,3)29-21-12-11-17-16-7-4-5-10-22(16)30-23(25(17)24(15)21)13-18-19(27)8-6-9-20(18)28/h4-14,29H,1-3H3/b23-13-
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31n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067683
PNG
(2,2,4-Trimethyl-5-[1-m-tolyl-meth-(Z)-ylidene]-2,5...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(C)c4)c3c12
Show InChI InChI=1S/C27H25NO/c1-17-8-7-9-19(14-17)15-24-26-21(20-10-5-6-11-23(20)29-24)12-13-22-25(26)18(2)16-27(3,4)28-22/h5-16,28H,1-4H3/b24-15-
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40n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067673
PNG
(5-[1-(3-Methoxy-phenyl)-meth-(Z)-ylidene]-2,2,4-tr...)
Show SMILES COc1cccc(\C=C2/Oc3ccccc3-c3ccc4NC(C)(C)C=C(C)c4c23)c1
Show InChI InChI=1S/C27H25NO2/c1-17-16-27(2,3)28-22-13-12-21-20-10-5-6-11-23(20)30-24(26(21)25(17)22)15-18-8-7-9-19(14-18)29-4/h5-16,28H,1-4H3/b24-15-
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53.3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067672
PNG
(5-[1-(4-Chloro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccc(Cl)cc4)c3c12
Show InChI InChI=1S/C26H22ClNO/c1-16-15-26(2,3)28-21-13-12-20-19-6-4-5-7-22(19)29-23(25(20)24(16)21)14-17-8-10-18(27)11-9-17/h4-15,28H,1-3H3/b23-14-
PDB

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60n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067677
PNG
(2,2,4-Trimethyl-5-[1-p-tolyl-meth-(Z)-ylidene]-2,5...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccc(C)cc4)c3c12
Show InChI InChI=1S/C27H25NO/c1-17-9-11-19(12-10-17)15-24-26-21(20-7-5-6-8-23(20)29-24)13-14-22-25(26)18(2)16-27(3,4)28-22/h5-16,28H,1-4H3/b24-15-
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70n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50067671
PNG
(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cc(F)ccc4F)c3c12
Show InChI InChI=1S/C26H21F2NO/c1-15-14-26(2,3)29-21-11-9-19-18-6-4-5-7-22(18)30-23(25(19)24(15)21)13-16-12-17(27)8-10-20(16)28/h4-14,29H,1-3H3/b23-13-
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173n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human glucocorticoid receptor expressed in SF-12 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50067670
PNG
(5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(F)c4)c3c12
Show InChI InChI=1S/C26H22FNO/c1-16-15-26(2,3)28-21-12-11-20-19-9-4-5-10-22(19)29-23(25(20)24(16)21)14-17-7-6-8-18(27)13-17/h4-15,28H,1-3H3/b23-14-
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180n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human glucocorticoid receptor expressed in SF-12 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50067668
PNG
(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4)c3c12
Show InChI InChI=1S/C26H23NO/c1-17-16-26(2,3)27-21-14-13-20-19-11-7-8-12-22(19)28-23(25(20)24(17)21)15-18-9-5-4-6-10-18/h4-16,27H,1-3H3/b23-15-
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299n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human glucocorticoid receptor expressed in SF-12 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50067684
PNG
(2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4C)c3c12
Show InChI InChI=1S/C27H25NO/c1-17-9-5-6-10-19(17)15-24-26-21(20-11-7-8-12-23(20)29-24)13-14-22-25(26)18(2)16-27(3,4)28-22/h5-16,28H,1-4H3/b24-15-
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564n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human glucocorticoid receptor expressed in SF-12 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Androgen receptor


(Homo sapiens (Human))
BDBM50067670
PNG
(5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(F)c4)c3c12
Show InChI InChI=1S/C26H22FNO/c1-16-15-26(2,3)28-21-12-11-20-19-9-4-5-10-22(19)29-23(25(20)24(16)21)14-17-7-6-8-18(27)13-17/h4-15,28H,1-3H3/b23-14-
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798n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human androgen receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Androgen receptor


(Homo sapiens (Human))
BDBM50067684
PNG
(2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4C)c3c12
Show InChI InChI=1S/C27H25NO/c1-17-9-5-6-10-19(17)15-24-26-21(20-11-7-8-12-23(20)29-24)13-14-22-25(26)18(2)16-27(3,4)28-22/h5-16,28H,1-4H3/b24-15-
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844n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human androgen receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Androgen receptor


(Homo sapiens (Human))
BDBM50067671
PNG
(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cc(F)ccc4F)c3c12
Show InChI InChI=1S/C26H21F2NO/c1-15-14-26(2,3)29-21-11-9-19-18-6-4-5-7-22(18)30-23(25(19)24(15)21)13-16-12-17(27)8-10-20(16)28/h4-14,29H,1-3H3/b23-13-
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887n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human androgen receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Androgen receptor


(Homo sapiens (Human))
BDBM50067668
PNG
(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4)c3c12
Show InChI InChI=1S/C26H23NO/c1-17-16-26(2,3)27-21-14-13-20-19-11-7-8-12-22(19)28-23(25(20)24(17)21)15-18-9-5-4-6-10-18/h4-16,27H,1-3H3/b23-15-
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2.66E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against human androgen receptor


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067675
PNG
(5-[1-(3-Bromo-phenyl)-meth-(Z)-ylidene]-2,2,4-trim...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(Br)c4)c3c12
Show InChI InChI=1S/C26H22BrNO/c1-16-15-26(2,3)28-21-12-11-20-19-9-4-5-10-22(19)29-23(25(20)24(16)21)14-17-7-6-8-18(27)13-17/h4-15,28H,1-3H3/b23-14-
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n/an/an/an/a 37n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cell


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067684
PNG
(2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4C)c3c12
Show InChI InChI=1S/C27H25NO/c1-17-9-5-6-10-19(17)15-24-26-21(20-11-7-8-12-23(20)29-24)13-14-22-25(26)18(2)16-27(3,4)28-22/h5-16,28H,1-4H3/b24-15-
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n/an/an/an/a 28n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Agonistic activity against human progesterone receptor in T47D breast cancer cells


J Med Chem 46: 4104-12 (2003)


Article DOI: 10.1021/jm020477g
BindingDB Entry DOI: 10.7270/Q2QZ29C6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067684
PNG
(2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4C)c3c12
Show InChI InChI=1S/C27H25NO/c1-17-9-5-6-10-19(17)15-24-26-21(20-11-7-8-12-23(20)29-24)13-14-22-25(26)18(2)16-27(3,4)28-22/h5-16,28H,1-4H3/b24-15-
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n/an/an/an/a 5.70n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Agonistic activity against human progesterone receptor in CV-1 cells


J Med Chem 46: 4104-12 (2003)


Article DOI: 10.1021/jm020477g
BindingDB Entry DOI: 10.7270/Q2QZ29C6
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067670
PNG
(5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(F)c4)c3c12
Show InChI InChI=1S/C26H22FNO/c1-16-15-26(2,3)28-21-12-11-20-19-9-4-5-10-22(19)29-23(25(20)24(16)21)14-17-7-6-8-18(27)13-17/h4-15,28H,1-3H3/b23-14-
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n/an/an/an/a 51n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Agonistic activity by cotransfection assay against human Progesterone receptor in T47D cells


J Med Chem 42: 1466-72 (1999)


Article DOI: 10.1021/jm980723h
BindingDB Entry DOI: 10.7270/Q2NK3FQ9
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067670
PNG
(5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(F)c4)c3c12
Show InChI InChI=1S/C26H22FNO/c1-16-15-26(2,3)28-21-12-11-20-19-9-4-5-10-22(19)29-23(25(20)24(16)21)14-17-7-6-8-18(27)13-17/h4-15,28H,1-3H3/b23-14-
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n/an/an/an/a 7.60n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Compound was tested for agonistic activity by cotransfection assay against human Progesterone receptor in CV-1 cells


J Med Chem 42: 1466-72 (1999)


Article DOI: 10.1021/jm980723h
BindingDB Entry DOI: 10.7270/Q2NK3FQ9
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067685
PNG
(5-[1-(2,6-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4c(F)cccc4F)c3c12
Show InChI InChI=1S/C26H21F2NO/c1-15-14-26(2,3)29-21-12-11-17-16-7-4-5-10-22(16)30-23(25(17)24(15)21)13-18-19(27)8-6-9-20(18)28/h4-14,29H,1-3H3/b23-13-
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n/an/an/an/a 32n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cell


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067677
PNG
(2,2,4-Trimethyl-5-[1-p-tolyl-meth-(Z)-ylidene]-2,5...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccc(C)cc4)c3c12
Show InChI InChI=1S/C27H25NO/c1-17-9-11-19(12-10-17)15-24-26-21(20-7-5-6-8-23(20)29-24)13-14-22-25(26)18(2)16-27(3,4)28-22/h5-16,28H,1-4H3/b24-15-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cell


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067668
PNG
(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4)c3c12
Show InChI InChI=1S/C26H23NO/c1-17-16-26(2,3)27-21-14-13-20-19-11-7-8-12-22(19)28-23(25(20)24(17)21)15-18-9-5-4-6-10-18/h4-16,27H,1-3H3/b23-15-
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n/an/an/an/a 24.4n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cell


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067683
PNG
(2,2,4-Trimethyl-5-[1-m-tolyl-meth-(Z)-ylidene]-2,5...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(C)c4)c3c12
Show InChI InChI=1S/C27H25NO/c1-17-8-7-9-19(14-17)15-24-26-21(20-10-5-6-11-23(20)29-24)12-13-22-25(26)18(2)16-27(3,4)28-22/h5-16,28H,1-4H3/b24-15-
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n/an/an/an/a 75n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cell


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067680
PNG
(5-[1-(2,4-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccc(F)cc4F)c3c12
Show InChI InChI=1S/C26H21F2NO/c1-15-14-26(2,3)29-21-11-10-19-18-6-4-5-7-22(18)30-23(25(19)24(15)21)12-16-8-9-17(27)13-20(16)28/h4-14,29H,1-3H3/b23-12-
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n/an/an/an/a 22n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cell


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067684
PNG
(2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4C)c3c12
Show InChI InChI=1S/C27H25NO/c1-17-9-5-6-10-19(17)15-24-26-21(20-11-7-8-12-23(20)29-24)13-14-22-25(26)18(2)16-27(3,4)28-22/h5-16,28H,1-4H3/b24-15-
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n/an/an/an/a 5.70n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cell


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Mineralocorticoid receptor


(Homo sapiens (Human))
BDBM50067668
PNG
(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4)c3c12
Show InChI InChI=1S/C26H23NO/c1-17-16-26(2,3)27-21-14-13-20-19-11-7-8-12-22(19)28-23(25(20)24(17)21)15-18-9-5-4-6-10-18/h4-16,27H,1-3H3/b23-15-
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n/an/a 3.00E+3n/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory activity (IC50) against human mineralocorticoid receptor expressed in CV-1 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50067668
PNG
(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4)c3c12
Show InChI InChI=1S/C26H23NO/c1-17-16-26(2,3)27-21-14-13-20-19-11-7-8-12-22(19)28-23(25(20)24(17)21)15-18-9-5-4-6-10-18/h4-16,27H,1-3H3/b23-15-
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n/an/a 737n/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory activity (IC50) against human glucocorticoid receptor expressed in CV-1 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50067670
PNG
(5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(F)c4)c3c12
Show InChI InChI=1S/C26H22FNO/c1-16-15-26(2,3)28-21-12-11-20-19-9-4-5-10-22(19)29-23(25(20)24(16)21)14-17-7-6-8-18(27)13-17/h4-15,28H,1-3H3/b23-14-
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n/an/a 458n/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory activity (IC50) against human glucocorticoid receptor expressed in CV-1 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Mineralocorticoid receptor


(Homo sapiens (Human))
BDBM50067671
PNG
(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cc(F)ccc4F)c3c12
Show InChI InChI=1S/C26H21F2NO/c1-15-14-26(2,3)29-21-11-9-19-18-6-4-5-7-22(18)30-23(25(19)24(15)21)13-16-12-17(27)8-10-20(16)28/h4-14,29H,1-3H3/b23-13-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory activity (IC50) against human mineralocorticoid receptor expressed in CV-1 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50067684
PNG
(2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4C)c3c12
Show InChI InChI=1S/C27H25NO/c1-17-9-5-6-10-19(17)15-24-26-21(20-11-7-8-12-23(20)29-24)13-14-22-25(26)18(2)16-27(3,4)28-22/h5-16,28H,1-4H3/b24-15-
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n/an/a 1.05E+3n/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory activity (IC50) against human glucocorticoid receptor expressed in CV-1 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Androgen receptor


(Homo sapiens (Human))
BDBM50067671
PNG
(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cc(F)ccc4F)c3c12
Show InChI InChI=1S/C26H21F2NO/c1-15-14-26(2,3)29-21-11-9-19-18-6-4-5-7-22(18)30-23(25(19)24(15)21)13-16-12-17(27)8-10-20(16)28/h4-14,29H,1-3H3/b23-13-
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n/an/a 1.60E+3n/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory activity (IC50) against human androgen receptor expressed in CV-1 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Mineralocorticoid receptor


(Homo sapiens (Human))
BDBM50067670
PNG
(5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(F)c4)c3c12
Show InChI InChI=1S/C26H22FNO/c1-16-15-26(2,3)28-21-12-11-20-19-9-4-5-10-22(19)29-23(25(20)24(16)21)14-17-7-6-8-18(27)13-17/h4-15,28H,1-3H3/b23-14-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory activity (IC50) against human mineralocorticoid receptor expressed in CV-1 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067669
PNG
(5-[1-(2-Chloro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4Cl)c3c12
Show InChI InChI=1S/C26H22ClNO/c1-16-15-26(2,3)28-21-13-12-19-18-9-5-7-11-22(18)29-23(25(19)24(16)21)14-17-8-4-6-10-20(17)27/h4-15,28H,1-3H3/b23-14-
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n/an/an/an/a 57.8n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cell


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Androgen receptor


(Homo sapiens (Human))
BDBM50067670
PNG
(5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cccc(F)c4)c3c12
Show InChI InChI=1S/C26H22FNO/c1-16-15-26(2,3)28-21-12-11-20-19-9-4-5-10-22(19)29-23(25(20)24(16)21)14-17-7-6-8-18(27)13-17/h4-15,28H,1-3H3/b23-14-
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n/an/a 795n/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory activity (IC50) against human androgen receptor expressed in CV-1 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50067671
PNG
(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cc(F)ccc4F)c3c12
Show InChI InChI=1S/C26H21F2NO/c1-15-14-26(2,3)29-21-11-9-19-18-6-4-5-7-22(18)30-23(25(19)24(15)21)13-16-12-17(27)8-10-20(16)28/h4-14,29H,1-3H3/b23-13-
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n/an/a 371n/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory activity (IC50) against human glucocorticoid receptor expressed in CV-1 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067672
PNG
(5-[1-(4-Chloro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccc(Cl)cc4)c3c12
Show InChI InChI=1S/C26H22ClNO/c1-16-15-26(2,3)28-21-13-12-20-19-6-4-5-7-22(19)29-23(25(20)24(16)21)14-17-8-10-18(27)11-9-17/h4-15,28H,1-3H3/b23-14-
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n/an/an/an/a 139n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cell


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Androgen receptor


(Homo sapiens (Human))
BDBM50067668
PNG
(2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccccc4)c3c12
Show InChI InChI=1S/C26H23NO/c1-17-16-26(2,3)27-21-14-13-20-19-11-7-8-12-22(19)28-23(25(20)24(17)21)15-18-9-5-4-6-10-18/h4-16,27H,1-3H3/b23-15-
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n/an/a 650n/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory activity (IC50) against human androgen receptor expressed in CV-1 cells


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067671
PNG
(5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4cc(F)ccc4F)c3c12
Show InChI InChI=1S/C26H21F2NO/c1-15-14-26(2,3)29-21-11-9-19-18-6-4-5-7-22(18)30-23(25(19)24(15)21)13-16-12-17(27)8-10-20(16)28/h4-14,29H,1-3H3/b23-13-
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n/an/an/an/a 15n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cell


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50067682
PNG
(5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccc(F)cc4)c3c12
Show InChI InChI=1S/C26H22FNO/c1-16-15-26(2,3)28-21-13-12-20-19-6-4-5-7-22(19)29-23(25(20)24(16)21)14-17-8-10-18(27)11-9-17/h4-15,28H,1-3H3/b23-14-
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n/an/an/an/a 60n/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cell


J Med Chem 41: 4354-9 (1998)


Article DOI: 10.1021/jm980366a
BindingDB Entry DOI: 10.7270/Q2V40TB5
More data for this
Ligand-Target Pair
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