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1 similar compounds to monomer 50085858

Compile data set for download or QSAR
Wt: 394.8
BDBM50085859

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085859   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
EDNRA


(RAT)
BDBM50085859
PNG
((2-Chloro-phenyl)-[2-cyano-5-(pyridin-4-ylmethoxy)...)
Show SMILES OC(=O)C(Oc1cc(OCc2ccncc2)ccc1C#N)c1ccccc1Cl
Show InChI InChI=1S/C21H15ClN2O4/c22-18-4-2-1-3-17(18)20(21(25)26)28-19-11-16(6-5-15(19)12-23)27-13-14-7-9-24-10-8-14/h1-11,20H,13H2,(H,25,26)
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.


J Med Chem 43: 900-10 (2000)


Article DOI: 10.1021/jm990378b
BindingDB Entry DOI: 10.7270/Q2154G73
More data for this
Ligand-Target Pair