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6 similar compounds to monomer 50116272

Compile data set for download or QSAR
Wt: 372.4
BDBM50116273
Wt: 358.4
BDBM50116274
Wt: 400.4
BDBM50116276
Wt: 359.4
BDBM50116279
Wt: 400.4
BDBM50116280
Wt: 343.4
BDBM50116283

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50116273,50116274,50116276,50116279,50116280,50116283   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase 9


(Mus musculus)
BDBM50116273
PNG
(CHEMBL306862 | N-(2-Aminomethyl-3H-benzoimidazol-5...)
Show SMILES NCc1nc2ccc(NC(=O)c3ccccc3OCc3ccccc3)cc2[nH]1
Show InChI InChI=1S/C22H20N4O2/c23-13-21-25-18-11-10-16(12-19(18)26-21)24-22(27)17-8-4-5-9-20(17)28-14-15-6-2-1-3-7-15/h1-12H,13-14,23H2,(H,24,27)(H,25,26)
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PubMed
n/an/a 4.80E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration was determined against murine gelatinase B


Bioorg Med Chem Lett 12: 2201-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00365-7
BindingDB Entry DOI: 10.7270/Q2RR1XK6
More data for this
Ligand-Target Pair
Matrix metalloproteinase 9


(Mus musculus)
BDBM50116274
PNG
((2-Aminomethyl-3H-benzoimidazol-5-yl)-(4-benzyloxy...)
Show SMILES NCc1nc2ccc(NCc3ccc(OCc4ccccc4)cc3)cc2[nH]1
Show InChI InChI=1S/C22H22N4O/c23-13-22-25-20-11-8-18(12-21(20)26-22)24-14-16-6-9-19(10-7-16)27-15-17-4-2-1-3-5-17/h1-12,24H,13-15,23H2,(H,25,26)
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n/an/a 5.10E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration was determined against murine gelatinase B


Bioorg Med Chem Lett 12: 2201-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00365-7
BindingDB Entry DOI: 10.7270/Q2RR1XK6
More data for this
Ligand-Target Pair
Matrix metalloproteinase 9


(Mus musculus)
BDBM50116283
PNG
((2-Benzyloxy-benzyl)-(2-methyl-1H-benzoimidazol-5-...)
Show SMILES Cc1nc2ccc(NCc3ccccc3OCc3ccccc3)cc2[nH]1
Show InChI InChI=1S/C22H21N3O/c1-16-24-20-12-11-19(13-21(20)25-16)23-14-18-9-5-6-10-22(18)26-15-17-7-3-2-4-8-17/h2-13,23H,14-15H2,1H3,(H,24,25)
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n/an/a>3.00E+5n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration was determined against murine gelatinase B


Bioorg Med Chem Lett 12: 2201-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00365-7
BindingDB Entry DOI: 10.7270/Q2RR1XK6
More data for this
Ligand-Target Pair
Matrix metalloproteinase 9


(Mus musculus)
BDBM50116279
PNG
(CHEMBL71110 | [5-(2-Benzyloxy-benzylamino)-1H-benz...)
Show SMILES OCc1nc2ccc(NCc3ccccc3OCc3ccccc3)cc2[nH]1
Show InChI InChI=1S/C22H21N3O2/c26-14-22-24-19-11-10-18(12-20(19)25-22)23-13-17-8-4-5-9-21(17)27-15-16-6-2-1-3-7-16/h1-12,23,26H,13-15H2,(H,24,25)
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration was determined against murine gelatinase B


Bioorg Med Chem Lett 12: 2201-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00365-7
BindingDB Entry DOI: 10.7270/Q2RR1XK6
More data for this
Ligand-Target Pair
Matrix metalloproteinase 9


(Mus musculus)
BDBM50116280
PNG
(CHEMBL73117 | N-(2-Aminomethyl-3H-benzoimidazol-5-...)
Show SMILES CC(=O)N(Cc1ccccc1OCc1ccccc1)c1ccc2nc(CN)[nH]c2c1
Show InChI InChI=1S/C24H24N4O2/c1-17(29)28(20-11-12-21-22(13-20)27-24(14-25)26-21)15-19-9-5-6-10-23(19)30-16-18-7-3-2-4-8-18/h2-13H,14-16,25H2,1H3,(H,26,27)
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n/an/a 8.30E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration was determined against murine gelatinase B


Bioorg Med Chem Lett 12: 2201-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00365-7
BindingDB Entry DOI: 10.7270/Q2RR1XK6
More data for this
Ligand-Target Pair
Matrix metalloproteinase 9


(Mus musculus)
BDBM50116276
PNG
(CHEMBL71547 | N-[5-(2-Benzyloxy-benzylamino)-1H-be...)
Show SMILES CC(=O)NCc1nc2ccc(NCc3ccccc3OCc3ccccc3)cc2[nH]1
Show InChI InChI=1S/C24H24N4O2/c1-17(29)25-15-24-27-21-12-11-20(13-22(21)28-24)26-14-19-9-5-6-10-23(19)30-16-18-7-3-2-4-8-18/h2-13,26H,14-16H2,1H3,(H,25,29)(H,27,28)
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PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration was determined against murine gelatinase B


Bioorg Med Chem Lett 12: 2201-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00365-7
BindingDB Entry DOI: 10.7270/Q2RR1XK6
More data for this
Ligand-Target Pair