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15 similar compounds to monomer 50137475

Compile data set for download or QSAR
Wt: 335.3
BDBM50137499
Wt: 373.4
BDBM50137500
Wt: 335.3
BDBM50137502
Wt: 309.3
BDBM50137505
Wt: 309.3
BDBM50137458
Wt: 293.3
BDBM50137461
Wt: 324.3
BDBM50137477
Wt: 321.3
BDBM50137480
Wt: 310.3
BDBM50137481
Wt: 307.3
BDBM50137487
Wt: 281.3
BDBM50137489
Wt: 335.3
BDBM50137491
Wt: 320.3
BDBM50137492
Wt: 335.3
BDBM50137495
Wt: 371.4
BDBM50137496

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50137499,50137500,50137502,50137505,50137458,50137461,50137477,50137480,50137481,50137487,50137489,50137491,50137492,50137495,50137496   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137481
PNG
(1-Cyclohexyl-2-(1H-imidazol-2-yl)-1H-benzoimidazol...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ncc[nH]1
Show InChI InChI=1S/C17H18N4O2/c22-17(23)11-6-7-14-13(10-11)20-16(15-18-8-9-19-15)21(14)12-4-2-1-3-5-12/h6-10,12H,1-5H2,(H,18,19)(H,22,23)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
RNA polymerase subunit beta (β-RNAP)


(Escherichia coli)
BDBM50137480
PNG
(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C19H19N3O2/c23-19(24)13-9-10-17-16(12-13)21-18(15-8-4-5-11-20-15)22(17)14-6-2-1-3-7-14/h4-5,8-12,14H,1-3,6-7H2,(H,23,24)
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n/an/a>5.00E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against calf thymus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137458
PNG
(1-Cyclohexyl-2-(1H-pyrrol-2-yl)-1H-benzoimidazole-...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc[nH]1
Show InChI InChI=1S/C18H19N3O2/c22-18(23)12-8-9-16-15(11-12)20-17(14-7-4-10-19-14)21(16)13-5-2-1-3-6-13/h4,7-11,13,19H,1-3,5-6H2,(H,22,23)
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n/an/a 5.90E+3n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137480
PNG
(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C19H19N3O2/c23-19(24)13-9-10-17-16(12-13)21-18(15-8-4-5-11-20-15)22(17)14-6-2-1-3-7-14/h4-5,8-12,14H,1-3,6-7H2,(H,23,24)
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n/an/a 4.30E+3n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137489
PNG
(1-Isopropyl-2-pyridin-2-yl-1H-benzoimidazole-5-car...)
Show SMILES CC(C)n1c(nc2cc(ccc12)C(O)=O)-c1ccccn1
Show InChI InChI=1S/C16H15N3O2/c1-10(2)19-14-7-6-11(16(20)21)9-13(14)18-15(19)12-5-3-4-8-17-12/h3-10H,1-2H3,(H,20,21)
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n/an/a 4.08E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137491
PNG
(1-(4-Methyl-cyclohexyl)-2-pyridin-2-yl-1H-benzoimi...)
Show SMILES CC1CCC(CC1)n1c(nc2cc(ccc12)C(O)=O)-c1ccccn1
Show InChI InChI=1S/C20H21N3O2/c1-13-5-8-15(9-6-13)23-18-10-7-14(20(24)25)12-17(18)22-19(23)16-4-2-3-11-21-16/h2-4,7,10-13,15H,5-6,8-9H2,1H3,(H,24,25)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137492
PNG
(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES NC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C19H20N4O/c20-18(24)13-9-10-17-16(12-13)22-19(15-8-4-5-11-21-15)23(17)14-6-2-1-3-7-14/h4-5,8-12,14H,1-3,6-7H2,(H2,20,24)
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n/an/a 2.70E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137505
PNG
(1-(1-Ethyl-propyl)-2-pyridin-2-yl-1H-benzoimidazol...)
Show SMILES CCC(CC)n1c(nc2cc(ccc12)C(O)=O)-c1ccccn1
Show InChI InChI=1S/C18H19N3O2/c1-3-13(4-2)21-16-9-8-12(18(22)23)11-15(16)20-17(21)14-7-5-6-10-19-14/h5-11,13H,3-4H2,1-2H3,(H,22,23)
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n/an/a 1.39E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137477
PNG
(1-Cyclohexyl-2-(5-methyl-3H-imidazol-4-yl)-1H-benz...)
Show SMILES Cc1[nH]cnc1-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C18H20N4O2/c1-11-16(20-10-19-11)17-21-14-9-12(18(23)24)7-8-15(14)22(17)13-5-3-2-4-6-13/h7-10,13H,2-6H2,1H3,(H,19,20)(H,23,24)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137461
PNG
(1-Cyclobutyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES OC(=O)c1ccc2n(C3CCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C17H15N3O2/c21-17(22)11-7-8-15-14(10-11)19-16(13-6-1-2-9-18-13)20(15)12-4-3-5-12/h1-2,6-10,12H,3-5H2,(H,21,22)
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n/an/a 7.60E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137499
PNG
(1-(2-Methyl-cyclohexyl)-2-pyridin-2-yl-1H-benzoimi...)
Show SMILES CC1CCCCC1n1c(nc2cc(ccc12)C(O)=O)-c1ccccn1
Show InChI InChI=1S/C20H21N3O2/c1-13-6-2-3-8-17(13)23-18-10-9-14(20(24)25)12-16(18)22-19(23)15-7-4-5-11-21-15/h4-5,7,9-13,17H,2-3,6,8H2,1H3,(H,24,25)
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n/an/a 1.30E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137495
PNG
(1-Cyclohexyl-2-(6-methyl-pyridin-2-yl)-1H-benzoimi...)
Show SMILES Cc1cccc(n1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C20H21N3O2/c1-13-6-5-9-16(21-13)19-22-17-12-14(20(24)25)10-11-18(17)23(19)15-7-3-2-4-8-15/h5-6,9-12,15H,2-4,7-8H2,1H3,(H,24,25)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137502
PNG
(1-Cycloheptyl-2-pyridin-2-yl-1H-benzoimidazole-5-c...)
Show SMILES OC(=O)c1ccc2n(C3CCCCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C20H21N3O2/c24-20(25)14-10-11-18-17(13-14)22-19(16-9-5-6-12-21-16)23(18)15-7-3-1-2-4-8-15/h5-6,9-13,15H,1-4,7-8H2,(H,24,25)
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n/an/a 4.90E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137496
PNG
(1-Cyclohexyl-2-quinolin-2-yl-1H-benzoimidazole-5-c...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc2ccccc2n1
Show InChI InChI=1S/C23H21N3O2/c27-23(28)16-11-13-21-20(14-16)25-22(26(21)17-7-2-1-3-8-17)19-12-10-15-6-4-5-9-18(15)24-19/h4-6,9-14,17H,1-3,7-8H2,(H,27,28)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137500
PNG
(1-Cyclohexyl-2-(3-methyl-1H-indol-2-yl)-1H-benzoim...)
Show SMILES Cc1c([nH]c2ccccc12)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C23H23N3O2/c1-14-17-9-5-6-10-18(17)24-21(14)22-25-19-13-15(23(27)28)11-12-20(19)26(22)16-7-3-2-4-8-16/h5-6,9-13,16,24H,2-4,7-8H2,1H3,(H,27,28)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Poliovirus type 1 polyprotein


(Poliovirus type 1 (strain Mahoney))
BDBM50137458
PNG
(1-Cyclohexyl-2-(1H-pyrrol-2-yl)-1H-benzoimidazole-...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc[nH]1
Show InChI InChI=1S/C18H19N3O2/c22-18(23)12-8-9-16-15(11-12)20-17(14-7-4-10-19-14)21(16)13-5-2-1-3-6-13/h4,7-11,13,19H,1-3,5-6H2,(H,22,23)
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n/an/a>5.00E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against polio virus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Poliovirus type 1 polyprotein


(Poliovirus type 1 (strain Mahoney))
BDBM50137481
PNG
(1-Cyclohexyl-2-(1H-imidazol-2-yl)-1H-benzoimidazol...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ncc[nH]1
Show InChI InChI=1S/C17H18N4O2/c22-17(23)11-6-7-14-13(10-11)20-16(15-18-8-9-19-15)21(14)12-4-2-1-3-5-12/h6-10,12H,1-5H2,(H,18,19)(H,22,23)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against polio virus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Poliovirus type 1 polyprotein


(Poliovirus type 1 (strain Mahoney))
BDBM50137487
PNG
(1-Cyclopentyl-2-pyridin-2-yl-1H-benzoimidazole-5-c...)
Show SMILES OC(=O)c1ccc2n(C3CCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C18H17N3O2/c22-18(23)12-8-9-16-15(11-12)20-17(14-7-3-4-10-19-14)21(16)13-5-1-2-6-13/h3-4,7-11,13H,1-2,5-6H2,(H,22,23)
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n/an/a>5.00E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against polio virus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Poliovirus type 1 polyprotein


(Poliovirus type 1 (strain Mahoney))
BDBM50137499
PNG
(1-(2-Methyl-cyclohexyl)-2-pyridin-2-yl-1H-benzoimi...)
Show SMILES CC1CCCCC1n1c(nc2cc(ccc12)C(O)=O)-c1ccccn1
Show InChI InChI=1S/C20H21N3O2/c1-13-6-2-3-8-17(13)23-18-10-9-14(20(24)25)12-16(18)22-19(23)15-7-4-5-11-21-15/h4-5,7,9-13,17H,2-3,6,8H2,1H3,(H,24,25)
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n/an/a>5.00E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against polio virus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Poliovirus type 1 polyprotein


(Poliovirus type 1 (strain Mahoney))
BDBM50137480
PNG
(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C19H19N3O2/c23-19(24)13-9-10-17-16(12-13)21-18(15-8-4-5-11-20-15)22(17)14-6-2-1-3-7-14/h4-5,8-12,14H,1-3,6-7H2,(H,23,24)
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n/an/a>5.00E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against polio virus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C virus (HCV))
BDBM50137480
PNG
(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C19H19N3O2/c23-19(24)13-9-10-17-16(12-13)21-18(15-8-4-5-11-20-15)22(17)14-6-2-1-3-7-14/h4-5,8-12,14H,1-3,6-7H2,(H,23,24)
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n/an/a 4.30E+3n/an/an/an/an/an/a



University of Wollongong

Curated by ChEMBL


Assay Description
Inhibitory concentration against hepatitis C virus polymerase


J Med Chem 48: 1-20 (2005)


Article DOI: 10.1021/jm0400101
BindingDB Entry DOI: 10.7270/Q2XP75Q1
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137480
PNG
(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C19H19N3O2/c23-19(24)13-9-10-17-16(12-13)21-18(15-8-4-5-11-20-15)22(17)14-6-2-1-3-7-14/h4-5,8-12,14H,1-3,6-7H2,(H,23,24)
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n/an/a 2.70E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPA


Bioorg Med Chem Lett 16: 4987-93 (2006)

Checked by Author
Article DOI: 10.1016/j.bmcl.2006.07.074
BindingDB Entry DOI: 10.7270/Q27S7PJT
More data for this
Ligand-Target Pair
RNA polymerase subunit beta (β-RNAP)


(Escherichia coli)
BDBM50137458
PNG
(1-Cyclohexyl-2-(1H-pyrrol-2-yl)-1H-benzoimidazole-...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc[nH]1
Show InChI InChI=1S/C18H19N3O2/c22-18(23)12-8-9-16-15(11-12)20-17(14-7-4-10-19-14)21(16)13-5-2-1-3-6-13/h4,7-11,13,19H,1-3,5-6H2,(H,22,23)
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n/an/a>5.00E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against calf thymus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
RNA polymerase subunit beta (β-RNAP)


(Escherichia coli)
BDBM50137481
PNG
(1-Cyclohexyl-2-(1H-imidazol-2-yl)-1H-benzoimidazol...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ncc[nH]1
Show InChI InChI=1S/C17H18N4O2/c22-17(23)11-6-7-14-13(10-11)20-16(15-18-8-9-19-15)21(14)12-4-2-1-3-5-12/h6-10,12H,1-5H2,(H,18,19)(H,22,23)
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n/an/a>5.00E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against calf thymus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137487
PNG
(1-Cyclopentyl-2-pyridin-2-yl-1H-benzoimidazole-5-c...)
Show SMILES OC(=O)c1ccc2n(C3CCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C18H17N3O2/c22-18(23)12-8-9-16-15(11-12)20-17(14-7-3-4-10-19-14)21(16)13-5-1-2-6-13/h3-4,7-11,13H,1-2,5-6H2,(H,22,23)
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n/an/a 1.20E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair