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13 similar compounds to monomer 50162869

Compile data set for download or QSAR
Wt: 443.5
BDBM50162861
Wt: 439.5
BDBM50162864
Wt: 425.5
BDBM50162866
Wt: 399.5
BDBM50162867
Wt: 411.5
BDBM50162868
Wt: 385.5
BDBM50162870
Wt: 443.5
BDBM50162871
Wt: 413.5
BDBM50166031
Wt: 413.5
BDBM50166019
Wt: 443.5
BDBM50166023
Wt: 443.5
BDBM50166024
Wt: 443.5
BDBM50166025
Wt: 443.5
BDBM50166027

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50162861,50162864,50162866,50162867,50162868,50162870,50162871,50166031,50166019,50166023,50166024,50166025,50166027   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50166031
PNG
(CHEMBL427173 | Naphthalene-2-carboxylic acid [(S)-...)
Show SMILES O=C(NCCCCN1CCN2[C@@H](CCc3ccccc23)C1)c1ccc2ccccc2c1
Show InChI InChI=1S/C27H31N3O/c31-27(24-12-11-21-7-1-2-9-23(21)19-24)28-15-5-6-16-29-17-18-30-25(20-29)14-13-22-8-3-4-10-26(22)30/h1-4,7-12,19,25H,5-6,13-18,20H2,(H,28,31)/t25-/m0/s1
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16n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PD 128907 binding to Dopamine receptor D3 in rat ventral striatum


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50166019
PNG
(CHEMBL191815 | Naphthalene-2-carboxylic acid [(R)-...)
Show SMILES O=C(NCCCCN1CCN2[C@H](CCc3ccccc23)C1)c1ccc2ccccc2c1
Show InChI InChI=1S/C27H31N3O/c31-27(24-12-11-21-7-1-2-9-23(21)19-24)28-15-5-6-16-29-17-18-30-25(20-29)14-13-22-8-3-4-10-26(22)30/h1-4,7-12,19,25H,5-6,13-18,20H2,(H,28,31)/t25-/m1/s1
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19n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PD 128907 binding to Dopamine receptor D3 in rat ventral striatum


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50162864
PNG
(Biphenyl-4-carboxylic acid [4-(1,2,4,4a,5,6-hexahy...)
Show SMILES O=C(NCCCCN1CCN2C(CCc3ccccc23)C1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C29H33N3O/c33-29(26-14-12-24(13-15-26)23-8-2-1-3-9-23)30-18-6-7-19-31-20-21-32-27(22-31)17-16-25-10-4-5-11-28(25)32/h1-5,8-15,27H,6-7,16-22H2,(H,30,33)
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22n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity D3 [3H]-PD 128907 receptor was determined using caudate-putamen of adult male Spragueo?=Dawley rats


Bioorg Med Chem Lett 15: 1701-5 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.037
BindingDB Entry DOI: 10.7270/Q2862FXD
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50166027
PNG
(CHEMBL363406 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1ccc2CC[C@@H]3CN(CCCCNC(=O)c4ccc5ccccc5c4)CCN3c2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-13-11-22-10-12-25-20-30(16-17-31(25)27(22)19-26)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-23(21)18-24/h2-3,6-9,11,13,18-19,25H,4-5,10,12,14-17,20H2,1H3,(H,29,32)/t25-/m1/s1
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44n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PD 128907 binding to Dopamine receptor D3 in rat ventral striatum


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50162861
PNG
(CHEMBL179781 | Naphthalene-2-carboxylic acid [4-(9...)
Show SMILES COc1ccc2CCC3CN(CCCCNC(=O)c4ccc5ccccc5c4)CCN3c2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-13-11-22-10-12-25-20-30(16-17-31(25)27(22)19-26)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-23(21)18-24/h2-3,6-9,11,13,18-19,25H,4-5,10,12,14-17,20H2,1H3,(H,29,32)
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45n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity D3 [3H]-PD 128907 receptor was determined using caudate-putamen of adult male Spragueo?=Dawley rats


Bioorg Med Chem Lett 15: 1701-5 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.037
BindingDB Entry DOI: 10.7270/Q2862FXD
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50166024
PNG
(CHEMBL192138 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1ccc2N3CCN(CCCCNC(=O)c4ccc5ccccc5c4)C[C@H]3CCc2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-12-13-27-23(19-26)10-11-25-20-30(16-17-31(25)27)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-22(21)18-24/h2-3,6-9,12-13,18-19,25H,4-5,10-11,14-17,20H2,1H3,(H,29,32)/t25-/m1/s1
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67n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PD 128907 binding to Dopamine receptor D3 in rat ventral striatum


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50166023
PNG
(CHEMBL192439 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1ccc2CC[C@H]3CN(CCCCNC(=O)c4ccc5ccccc5c4)CCN3c2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-13-11-22-10-12-25-20-30(16-17-31(25)27(22)19-26)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-23(21)18-24/h2-3,6-9,11,13,18-19,25H,4-5,10,12,14-17,20H2,1H3,(H,29,32)/t25-/m0/s1
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96n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PD 128907 binding to Dopamine receptor D3 in rat ventral striatum


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50166025
PNG
(CHEMBL193040 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1ccc2N3CCN(CCCCNC(=O)c4ccc5ccccc5c4)C[C@@H]3CCc2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-12-13-27-23(19-26)10-11-25-20-30(16-17-31(25)27)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-22(21)18-24/h2-3,6-9,12-13,18-19,25H,4-5,10-11,14-17,20H2,1H3,(H,29,32)/t25-/m0/s1
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126n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PD 128907 binding to Dopamine receptor D3 in rat ventral striatum


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50166031
PNG
(CHEMBL427173 | Naphthalene-2-carboxylic acid [(S)-...)
Show SMILES O=C(NCCCCN1CCN2[C@@H](CCc3ccccc23)C1)c1ccc2ccccc2c1
Show InChI InChI=1S/C27H31N3O/c31-27(24-12-11-21-7-1-2-9-23(21)19-24)28-15-5-6-16-29-17-18-30-25(20-29)14-13-22-8-3-4-10-26(22)30/h1-4,7-12,19,25H,5-6,13-18,20H2,(H,28,31)/t25-/m0/s1
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180n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Spiperone binding to Dopamine receptor D2-like in rat caudate-putamen membrane


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50162871
PNG
(CHEMBL361756 | Naphthalene-2-carboxylic acid [4-(8...)
Show SMILES COc1ccc2N3CCN(CCCCNC(=O)c4ccc5ccccc5c4)CC3CCc2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-12-13-27-23(19-26)10-11-25-20-30(16-17-31(25)27)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-22(21)18-24/h2-3,6-9,12-13,18-19,25H,4-5,10-11,14-17,20H2,1H3,(H,29,32)
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244n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity D3 [3H]-PD 128907 receptor was determined using caudate-putamen of adult male Spragueo?=Dawley rats


Bioorg Med Chem Lett 15: 1701-5 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.037
BindingDB Entry DOI: 10.7270/Q2862FXD
More data for this
Ligand-Target Pair
Dopamine D1B


(RAT)
BDBM50166031
PNG
(CHEMBL427173 | Naphthalene-2-carboxylic acid [(S)-...)
Show SMILES O=C(NCCCCN1CCN2[C@@H](CCc3ccccc23)C1)c1ccc2ccccc2c1
Show InChI InChI=1S/C27H31N3O/c31-27(24-12-11-21-7-1-2-9-23(21)19-24)28-15-5-6-16-29-17-18-30-25(20-29)14-13-22-8-3-4-10-26(22)30/h1-4,7-12,19,25H,5-6,13-18,20H2,(H,28,31)/t25-/m0/s1
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258n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1-like in rat brain


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50166019
PNG
(CHEMBL191815 | Naphthalene-2-carboxylic acid [(R)-...)
Show SMILES O=C(NCCCCN1CCN2[C@H](CCc3ccccc23)C1)c1ccc2ccccc2c1
Show InChI InChI=1S/C27H31N3O/c31-27(24-12-11-21-7-1-2-9-23(21)19-24)28-15-5-6-16-29-17-18-30-25(20-29)14-13-22-8-3-4-10-26(22)30/h1-4,7-12,19,25H,5-6,13-18,20H2,(H,28,31)/t25-/m1/s1
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585n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Spiperone binding to Dopamine receptor D2-like in rat caudate-putamen membrane


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50166023
PNG
(CHEMBL192439 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1ccc2CC[C@H]3CN(CCCCNC(=O)c4ccc5ccccc5c4)CCN3c2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-13-11-22-10-12-25-20-30(16-17-31(25)27(22)19-26)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-23(21)18-24/h2-3,6-9,11,13,18-19,25H,4-5,10,12,14-17,20H2,1H3,(H,29,32)/t25-/m0/s1
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990n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Spiperone binding to Dopamine receptor D2-like in rat caudate-putamen membrane


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50162867
PNG
(CHEMBL180107 | Naphthalene-2-carboxylic acid [3-(1...)
Show SMILES O=C(NCCCN1CCN2C(CCc3ccccc23)C1)c1ccc2ccccc2c1
Show InChI InChI=1S/C26H29N3O/c30-26(23-11-10-20-6-1-2-8-22(20)18-23)27-14-5-15-28-16-17-29-24(19-28)13-12-21-7-3-4-9-25(21)29/h1-4,6-11,18,24H,5,12-17,19H2,(H,27,30)
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1.54E+3n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity D3 [3H]-PD 128907 receptor was determined using caudate-putamen of adult male Spragueo?=Dawley rats


Bioorg Med Chem Lett 15: 1701-5 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.037
BindingDB Entry DOI: 10.7270/Q2862FXD
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50162870
PNG
(CHEMBL179805 | Naphthalene-2-carboxylic acid [2-(1...)
Show SMILES O=C(NCCN1CCN2C(CCc3ccccc23)C1)c1ccc2ccccc2c1
Show InChI InChI=1S/C25H27N3O/c29-25(22-10-9-19-5-1-2-7-21(19)17-22)26-13-14-27-15-16-28-23(18-27)12-11-20-6-3-4-8-24(20)28/h1-10,17,23H,11-16,18H2,(H,26,29)
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1.65E+3n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity D3 [3H]-PD 128907 receptor was determined using caudate-putamen of adult male Spragueo?=Dawley rats


Bioorg Med Chem Lett 15: 1701-5 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.037
BindingDB Entry DOI: 10.7270/Q2862FXD
More data for this
Ligand-Target Pair
Dopamine D1B


(RAT)
BDBM50166019
PNG
(CHEMBL191815 | Naphthalene-2-carboxylic acid [(R)-...)
Show SMILES O=C(NCCCCN1CCN2[C@H](CCc3ccccc23)C1)c1ccc2ccccc2c1
Show InChI InChI=1S/C27H31N3O/c31-27(24-12-11-21-7-1-2-9-23(21)19-24)28-15-5-6-16-29-17-18-30-25(20-29)14-13-22-8-3-4-10-26(22)30/h1-4,7-12,19,25H,5-6,13-18,20H2,(H,28,31)/t25-/m1/s1
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1.71E+3n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1-like in rat brain


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50166027
PNG
(CHEMBL363406 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1ccc2CC[C@@H]3CN(CCCCNC(=O)c4ccc5ccccc5c4)CCN3c2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-13-11-22-10-12-25-20-30(16-17-31(25)27(22)19-26)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-23(21)18-24/h2-3,6-9,11,13,18-19,25H,4-5,10,12,14-17,20H2,1H3,(H,29,32)/t25-/m1/s1
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1.72E+3n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Spiperone binding to Dopamine receptor D2-like in rat caudate-putamen membrane


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50162866
PNG
(Biphenyl-4-carboxylic acid [3-(1,2,4,4a,5,6-hexahy...)
Show SMILES O=C(NCCCN1CCN2C(CCc3ccccc23)C1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C28H31N3O/c32-28(25-13-11-23(12-14-25)22-7-2-1-3-8-22)29-17-6-18-30-19-20-31-26(21-30)16-15-24-9-4-5-10-27(24)31/h1-5,7-14,26H,6,15-21H2,(H,29,32)
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2.52E+3n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity D3 [3H]-PD 128907 receptor was determined using caudate-putamen of adult male Spragueo?=Dawley rats


Bioorg Med Chem Lett 15: 1701-5 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.037
BindingDB Entry DOI: 10.7270/Q2862FXD
More data for this
Ligand-Target Pair
Dopamine D1B


(RAT)
BDBM50166023
PNG
(CHEMBL192439 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1ccc2CC[C@H]3CN(CCCCNC(=O)c4ccc5ccccc5c4)CCN3c2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-13-11-22-10-12-25-20-30(16-17-31(25)27(22)19-26)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-23(21)18-24/h2-3,6-9,11,13,18-19,25H,4-5,10,12,14-17,20H2,1H3,(H,29,32)/t25-/m0/s1
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PubMed
4.33E+3n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1-like in rat brain


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine D1B


(RAT)
BDBM50166027
PNG
(CHEMBL363406 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1ccc2CC[C@@H]3CN(CCCCNC(=O)c4ccc5ccccc5c4)CCN3c2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-13-11-22-10-12-25-20-30(16-17-31(25)27(22)19-26)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-23(21)18-24/h2-3,6-9,11,13,18-19,25H,4-5,10,12,14-17,20H2,1H3,(H,29,32)/t25-/m1/s1
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PubMed
1.08E+4n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1-like in rat brain


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50162868
PNG
(Biphenyl-4-carboxylic acid [2-(1,2,4,4a,5,6-hexahy...)
Show SMILES O=C(NCCN1CCN2C(CCc3ccccc23)C1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C27H29N3O/c31-27(24-12-10-22(11-13-24)21-6-2-1-3-7-21)28-16-17-29-18-19-30-25(20-29)15-14-23-8-4-5-9-26(23)30/h1-13,25H,14-20H2,(H,28,31)
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PubMed
2.30E+4n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity D3 [3H]-PD 128907 receptor was determined using caudate-putamen of adult male Spragueo?=Dawley rats


Bioorg Med Chem Lett 15: 1701-5 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.037
BindingDB Entry DOI: 10.7270/Q2862FXD
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50166025
PNG
(CHEMBL193040 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1ccc2N3CCN(CCCCNC(=O)c4ccc5ccccc5c4)C[C@@H]3CCc2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-12-13-27-23(19-26)10-11-25-20-30(16-17-31(25)27)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-22(21)18-24/h2-3,6-9,12-13,18-19,25H,4-5,10-11,14-17,20H2,1H3,(H,29,32)/t25-/m0/s1
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PubMed
>5.00E+4n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Spiperone binding to Dopamine receptor D2-like in rat caudate-putamen membrane


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine D1B


(RAT)
BDBM50166025
PNG
(CHEMBL193040 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1ccc2N3CCN(CCCCNC(=O)c4ccc5ccccc5c4)C[C@@H]3CCc2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-12-13-27-23(19-26)10-11-25-20-30(16-17-31(25)27)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-22(21)18-24/h2-3,6-9,12-13,18-19,25H,4-5,10-11,14-17,20H2,1H3,(H,29,32)/t25-/m0/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1-like in rat brain


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine D1B


(RAT)
BDBM50166024
PNG
(CHEMBL192138 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1ccc2N3CCN(CCCCNC(=O)c4ccc5ccccc5c4)C[C@H]3CCc2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-12-13-27-23(19-26)10-11-25-20-30(16-17-31(25)27)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-22(21)18-24/h2-3,6-9,12-13,18-19,25H,4-5,10-11,14-17,20H2,1H3,(H,29,32)/t25-/m1/s1
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PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1-like in rat brain


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50166024
PNG
(CHEMBL192138 | Naphthalene-2-carboxylic acid [4-((...)
Show SMILES COc1ccc2N3CCN(CCCCNC(=O)c4ccc5ccccc5c4)C[C@H]3CCc2c1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-12-13-27-23(19-26)10-11-25-20-30(16-17-31(25)27)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-22(21)18-24/h2-3,6-9,12-13,18-19,25H,4-5,10-11,14-17,20H2,1H3,(H,29,32)/t25-/m1/s1
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PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Spiperone binding to Dopamine receptor D2-like in rat caudate-putamen membrane


J Med Chem 48: 3171-81 (2005)


Article DOI: 10.1021/jm049031l
BindingDB Entry DOI: 10.7270/Q2NZ874W
More data for this
Ligand-Target Pair