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2 similar compounds to monomer 50167869

Compile data set for download or QSAR
Wt: 428.9
BDBM50167873
Wt: 412.9
BDBM50167874

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50167873,50167874   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50167874
PNG
(3-Chloro-4-[4-(3-pyrimidin-2-yl-piperidin-1-yl)-bu...)
Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCCC(C1)c1ncccn1
Show InChI InChI=1S/C22H25ClN4O2/c23-20-16-29-19-9-2-1-8-18(19)22(28)27(20)14-4-3-12-26-13-5-7-17(15-26)21-24-10-6-11-25-21/h1-2,6,8-11,16-17H,3-5,7,12-15H2
KEGG

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 324n/an/an/an/an/an/a



Daiichi Suntory Biomedical Research Co., Ltd

Curated by ChEMBL


Assay Description
Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligand


Bioorg Med Chem Lett 15: 2990-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.059
BindingDB Entry DOI: 10.7270/Q21Z456V
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50167873
PNG
(3-Chloro-4-[4-(4-hydroxy-4-pyrimidin-2-yl-piperidi...)
Show SMILES OC1(CCN(CCCCN2C(Cl)=COc3ccccc3C2=O)CC1)c1ncccn1
Show InChI InChI=1S/C22H25ClN4O3/c23-19-16-30-18-7-2-1-6-17(18)20(28)27(19)13-4-3-12-26-14-8-22(29,9-15-26)21-24-10-5-11-25-21/h1-2,5-7,10-11,16,29H,3-4,8-9,12-15H2
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.65E+3n/an/an/an/an/an/a



Daiichi Suntory Biomedical Research Co., Ltd

Curated by ChEMBL


Assay Description
Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligand


Bioorg Med Chem Lett 15: 2990-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.059
BindingDB Entry DOI: 10.7270/Q21Z456V
More data for this
Ligand-Target Pair