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2 similar compounds to monomer 50176251

Compile data set for download or QSAR
Wt: 359.2
BDBM50176245
Wt: 359.2
BDBM50176254

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176245,50176254   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50176254
PNG
(2-((5,7-dichloro-1H-benzo[d]imidazol-2-yl)methyl)-...)
Show SMILES NC(=N)c1ccc2nc(Cc3nc4cc(Cl)cc(Cl)c4[nH]3)[nH]c2c1
Show InChI InChI=1S/C16H12Cl2N6/c17-8-4-9(18)15-12(5-8)23-14(24-15)6-13-21-10-2-1-7(16(19)20)3-11(10)22-13/h1-5H,6H2,(H3,19,20)(H,21,22)(H,23,24)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
3n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Binding affinity to FXa in presence of Zn2+


Bioorg Med Chem Lett 16: 710-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.023
BindingDB Entry DOI: 10.7270/Q2VM4BSJ
More data for this
Ligand-Target Pair
Coagulation factor X


(Homo sapiens (Human))
BDBM50176245
PNG
(2-((5,6-dichloro-1H-benzo[d]imidazol-2-yl)methyl)-...)
Show SMILES NC(=N)c1ccc2nc(Cc3nc4cc(Cl)c(Cl)cc4[nH]3)[nH]c2c1
Show InChI InChI=1S/C16H12Cl2N6/c17-8-4-12-13(5-9(8)18)24-15(23-12)6-14-21-10-2-1-7(16(19)20)3-11(10)22-14/h1-5H,6H2,(H3,19,20)(H,21,22)(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
140n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Binding affinity to FXa in presence of Zn2+


Bioorg Med Chem Lett 16: 710-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.023
BindingDB Entry DOI: 10.7270/Q2VM4BSJ
More data for this
Ligand-Target Pair