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4 similar compounds to monomer 50177368

Compile data set for download or QSAR
Wt: 498.6
BDBM50177363
Wt: 498.6
BDBM50177364
Wt: 498.6
BDBM50177365
Wt: 498.6
BDBM50177366

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50177363,50177364,50177365,50177366   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50177366
PNG
(CHEMBL201110 | N-(trans-4-(2-(8-methoxy-1,2,4,4a,5...)
Show SMILES COc1ccc2N3CCN(CC[C@H]4CC[C@@H](CC4)NC(=O)c4ccc5ncccc5c4)CC3CCc2c1
Show InChI InChI=1S/C31H38N4O2/c1-37-28-11-13-30-24(20-28)6-10-27-21-34(17-18-35(27)30)16-14-22-4-8-26(9-5-22)33-31(36)25-7-12-29-23(19-25)3-2-15-32-29/h2-3,7,11-13,15,19-20,22,26-27H,4-6,8-10,14,16-18,21H2,1H3,(H,33,36)/t22-,26-,27?
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
9.70n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Displacement of [3H]PD 128907 from rat ventral striatal membrane dopamine D3-like receptor


Bioorg Med Chem Lett 16: 443-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.053
BindingDB Entry DOI: 10.7270/Q2PR7VJK
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50177363
PNG
(CHEMBL199770 | N-(trans-4-(2-(8-methoxy-1,2,4,4a,5...)
Show SMILES COc1ccc2N3CCN(CC[C@H]4CC[C@@H](CC4)NC(=O)c4ccnc5ccccc45)CC3CCc2c1
Show InChI InChI=1S/C31H38N4O2/c1-37-26-12-13-30-23(20-26)8-11-25-21-34(18-19-35(25)30)17-15-22-6-9-24(10-7-22)33-31(36)28-14-16-32-29-5-3-2-4-27(28)29/h2-5,12-14,16,20,22,24-25H,6-11,15,17-19,21H2,1H3,(H,33,36)/t22-,24-,25?
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
16n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Displacement of [3H]PD 128907 from rat ventral striatal membrane dopamine D3-like receptor


Bioorg Med Chem Lett 16: 443-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.053
BindingDB Entry DOI: 10.7270/Q2PR7VJK
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50177365
PNG
(CHEMBL264520 | N-(trans-4-(2-(8-methoxy-1,2,4,4a,5...)
Show SMILES COc1ccc2N3CCN(CC[C@H]4CC[C@@H](CC4)NC(=O)c4cccc5cccnc45)CC3CCc2c1
Show InChI InChI=1S/C31H38N4O2/c1-37-27-13-14-29-24(20-27)9-12-26-21-34(18-19-35(26)29)17-15-22-7-10-25(11-8-22)33-31(36)28-6-2-4-23-5-3-16-32-30(23)28/h2-6,13-14,16,20,22,25-26H,7-12,15,17-19,21H2,1H3,(H,33,36)/t22-,25-,26?
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
87n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Displacement of [3H]PD 128907 from rat ventral striatal membrane dopamine D3-like receptor


Bioorg Med Chem Lett 16: 443-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.053
BindingDB Entry DOI: 10.7270/Q2PR7VJK
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50177364
PNG
(CHEMBL200183 | N-(trans-4-(2-(8-methoxy-1,2,4,4a,5...)
Show SMILES COc1ccc2N3CCN(CC[C@H]4CC[C@@H](CC4)NC(=O)c4ccc5ccccc5n4)CC3CCc2c1
Show InChI InChI=1S/C31H38N4O2/c1-37-27-13-15-30-24(20-27)8-12-26-21-34(18-19-35(26)30)17-16-22-6-10-25(11-7-22)32-31(36)29-14-9-23-4-2-3-5-28(23)33-29/h2-5,9,13-15,20,22,25-26H,6-8,10-12,16-19,21H2,1H3,(H,32,36)/t22-,25-,26?
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
183n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Displacement of [3H]PD 128907 from rat ventral striatal membrane dopamine D3-like receptor


Bioorg Med Chem Lett 16: 443-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.053
BindingDB Entry DOI: 10.7270/Q2PR7VJK
More data for this
Ligand-Target Pair