Found 37 hits for monomerid = 50178427,50178432,50259410,50259411,50259412,50259315 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Transmembrane domain-containing protein TMIGD3
(Homo sapiens (Human)) | BDBM50259315
(CHEMBL4069012)Show SMILES O=C(Nc1nc(cn2cc(nc12)-c1ccccc1)-c1ccccc1)c1cccnc1 Show InChI InChI=1S/C24H17N5O/c30-24(19-12-7-13-25-14-19)28-22-23-27-21(18-10-5-2-6-11-18)16-29(23)15-20(26-22)17-8-3-1-4-9-17/h1-16H,(H,26,28,30) | UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description
Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes after 120 mins by scintillation counting method |
Eur J Med Chem 125: 611-628 (2017)
BindingDB Entry DOI: 10.7270/Q2VM4FPF |
More data for this
Ligand-Target Pair | |
Cyclin-Dependent Kinase 9 (CDK9)
(Homo sapiens (Human)) | BDBM50259412
(CHEMBL4080844)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(\C=C\c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C19H19F3N4O/c1-2-15(12-27)24-17-8-9-18-23-11-16(26(18)25-17)7-6-13-4-3-5-14(10-13)19(20,21)22/h3-11,15,27H,2,12H2,1H3,(H,24,25)/b7-6+/t15-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK2/cyclin A after 30 mins by [gamma-33P]ATP based scintillation counting analysis |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual-specificity tyrosine-phosphorylation regulated kinase 2
(Homo sapiens (Human)) | BDBM50259411
(CHEMBL4086402)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C17H17F3N4O/c1-2-13(10-25)22-15-6-7-16-21-9-14(24(16)23-15)11-4-3-5-12(8-11)17(18,19)20/h3-9,13,25H,2,10H2,1H3,(H,22,23)/t13-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK2 expressed in Escherichia coli using using woodtide as substrate after 30 mins by [gamma-33P]ATP base... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK3
(Mus musculus) | BDBM50259410
(CHEMBL4100956)Show InChI InChI=1S/C15H17N5O/c1-2-12(10-21)18-14-5-6-15-17-9-13(20(15)19-14)11-4-3-7-16-8-11/h3-9,12,21H,2,10H2,1H3,(H,18,19)/t12-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant mouse CLK3 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK3
(Mus musculus) | BDBM50259412
(CHEMBL4080844)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(\C=C\c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C19H19F3N4O/c1-2-15(12-27)24-17-8-9-18-23-11-16(26(18)25-17)7-6-13-4-3-5-14(10-13)19(20,21)22/h3-11,15,27H,2,12H2,1H3,(H,24,25)/b7-6+/t15-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant mouse CLK3 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Mus musculus) | BDBM50259410
(CHEMBL4100956)Show InChI InChI=1S/C15H17N5O/c1-2-12(10-21)18-14-5-6-15-17-9-13(20(15)19-14)11-4-3-7-16-8-11/h3-9,12,21H,2,10H2,1H3,(H,18,19)/t12-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibitory concentration against dipeptidyl peptidase IV |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Mus musculus) | BDBM50259411
(CHEMBL4086402)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C17H17F3N4O/c1-2-13(10-25)22-15-6-7-16-21-9-14(24(16)23-15)11-4-3-5-12(8-11)17(18,19)20/h3-9,13,25H,2,10H2,1H3,(H,22,23)/t13-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibitory concentration against dipeptidyl peptidase IV |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Mus musculus) | BDBM50259412
(CHEMBL4080844)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(\C=C\c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C19H19F3N4O/c1-2-15(12-27)24-17-8-9-18-23-11-16(26(18)25-17)7-6-13-4-3-5-14(10-13)19(20,21)22/h3-11,15,27H,2,12H2,1H3,(H,24,25)/b7-6+/t15-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibitory concentration against dipeptidyl peptidase IV |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual-specificity tyrosine-phosphorylation regulated kinase 1A
(Homo sapiens (Human)) | BDBM50259410
(CHEMBL4100956)Show InChI InChI=1S/C15H17N5O/c1-2-12(10-21)18-14-5-6-15-17-9-13(20(15)19-14)11-4-3-7-16-8-11/h3-9,12,21H,2,10H2,1H3,(H,18,19)/t12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 870 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual-specificity tyrosine-phosphorylation regulated kinase 1A
(Homo sapiens (Human)) | BDBM50259411
(CHEMBL4086402)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C17H17F3N4O/c1-2-13(10-25)22-15-6-7-16-21-9-14(24(16)23-15)11-4-3-5-12(8-11)17(18,19)20/h3-9,13,25H,2,10H2,1H3,(H,22,23)/t13-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual-specificity tyrosine-phosphorylation regulated kinase 1A
(Homo sapiens (Human)) | BDBM50259412
(CHEMBL4080844)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(\C=C\c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C19H19F3N4O/c1-2-15(12-27)24-17-8-9-18-23-11-16(26(18)25-17)7-6-13-4-3-5-14(10-13)19(20,21)22/h3-11,15,27H,2,12H2,1H3,(H,24,25)/b7-6+/t15-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK4
(Mus musculus) | BDBM50259410
(CHEMBL4100956)Show InChI InChI=1S/C15H17N5O/c1-2-12(10-21)18-14-5-6-15-17-9-13(20(15)19-14)11-4-3-7-16-8-11/h3-9,12,21H,2,10H2,1H3,(H,18,19)/t12-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant mouse CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK4
(Mus musculus) | BDBM50259412
(CHEMBL4080844)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(\C=C\c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C19H19F3N4O/c1-2-15(12-27)24-17-8-9-18-23-11-16(26(18)25-17)7-6-13-4-3-5-14(10-13)19(20,21)22/h3-11,15,27H,2,12H2,1H3,(H,24,25)/b7-6+/t15-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant mouse CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50259410
(CHEMBL4100956)Show InChI InChI=1S/C15H17N5O/c1-2-12(10-21)18-14-5-6-15-17-9-13(20(15)19-14)11-4-3-7-16-8-11/h3-9,12,21H,2,10H2,1H3,(H,18,19)/t12-/m0/s1 | UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK1B expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50259411
(CHEMBL4086402)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C17H17F3N4O/c1-2-13(10-25)22-15-6-7-16-21-9-14(24(16)23-15)11-4-3-5-12(8-11)17(18,19)20/h3-9,13,25H,2,10H2,1H3,(H,22,23)/t13-/m0/s1 | UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK1B expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50259410
(CHEMBL4100956)Show InChI InChI=1S/C15H17N5O/c1-2-12(10-21)18-14-5-6-15-17-9-13(20(15)19-14)11-4-3-7-16-8-11/h3-9,12,21H,2,10H2,1H3,(H,18,19)/t12-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant mouse CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50259412
(CHEMBL4080844)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(\C=C\c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C19H19F3N4O/c1-2-15(12-27)24-17-8-9-18-23-11-16(26(18)25-17)7-6-13-4-3-5-14(10-13)19(20,21)22/h3-11,15,27H,2,12H2,1H3,(H,24,25)/b7-6+/t15-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]DAMGO binding to Opioid receptor mu |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual-specificity tyrosine-phosphorylation regulated kinase 3
(Homo sapiens (Human)) | BDBM50259411
(CHEMBL4086402)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C17H17F3N4O/c1-2-13(10-25)22-15-6-7-16-21-9-14(24(16)23-15)11-4-3-5-12(8-11)17(18,19)20/h3-9,13,25H,2,10H2,1H3,(H,22,23)/t13-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK3 expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based scin... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50259412
(CHEMBL4080844)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(\C=C\c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C19H19F3N4O/c1-2-15(12-27)24-17-8-9-18-23-11-16(26(18)25-17)7-6-13-4-3-5-14(10-13)19(20,21)22/h3-11,15,27H,2,12H2,1H3,(H,24,25)/b7-6+/t15-/m0/s1 | UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK1B expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK3
(Mus musculus) | BDBM50259411
(CHEMBL4086402)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C17H17F3N4O/c1-2-13(10-25)22-15-6-7-16-21-9-14(24(16)23-15)11-4-3-5-12(8-11)17(18,19)20/h3-9,13,25H,2,10H2,1H3,(H,22,23)/t13-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant mouse CLK3 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual-specificity tyrosine-phosphorylation regulated kinase 2
(Homo sapiens (Human)) | BDBM50259410
(CHEMBL4100956)Show InChI InChI=1S/C15H17N5O/c1-2-12(10-21)18-14-5-6-15-17-9-13(20(15)19-14)11-4-3-7-16-8-11/h3-9,12,21H,2,10H2,1H3,(H,18,19)/t12-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK2 expressed in Escherichia coli using using woodtide as substrate after 30 mins by [gamma-33P]ATP base... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual-specificity tyrosine-phosphorylation regulated kinase 2
(Homo sapiens (Human)) | BDBM50259412
(CHEMBL4080844)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(\C=C\c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C19H19F3N4O/c1-2-15(12-27)24-17-8-9-18-23-11-16(26(18)25-17)7-6-13-4-3-5-14(10-13)19(20,21)22/h3-11,15,27H,2,12H2,1H3,(H,24,25)/b7-6+/t15-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK2 expressed in Escherichia coli using using woodtide as substrate after 30 mins by [gamma-33P]ATP base... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50259411
(CHEMBL4086402)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C17H17F3N4O/c1-2-13(10-25)22-15-6-7-16-21-9-14(24(16)23-15)11-4-3-5-12(8-11)17(18,19)20/h3-9,13,25H,2,10H2,1H3,(H,22,23)/t13-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant mouse CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual-specificity tyrosine-phosphorylation regulated kinase 3
(Homo sapiens (Human)) | BDBM50259410
(CHEMBL4100956)Show InChI InChI=1S/C15H17N5O/c1-2-12(10-21)18-14-5-6-15-17-9-13(20(15)19-14)11-4-3-7-16-8-11/h3-9,12,21H,2,10H2,1H3,(H,18,19)/t12-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK3 expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based scin... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual-specificity tyrosine-phosphorylation regulated kinase 3
(Homo sapiens (Human)) | BDBM50259412
(CHEMBL4080844)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(\C=C\c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C19H19F3N4O/c1-2-15(12-27)24-17-8-9-18-23-11-16(26(18)25-17)7-6-13-4-3-5-14(10-13)19(20,21)22/h3-11,15,27H,2,12H2,1H3,(H,24,25)/b7-6+/t15-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK3 expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based scin... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK4
(Mus musculus) | BDBM50259411
(CHEMBL4086402)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C17H17F3N4O/c1-2-13(10-25)22-15-6-7-16-21-9-14(24(16)23-15)11-4-3-5-12(8-11)17(18,19)20/h3-9,13,25H,2,10H2,1H3,(H,22,23)/t13-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant mouse CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Transmembrane domain-containing protein TMIGD3
(Homo sapiens (Human)) | BDBM50259315
(CHEMBL4069012)Show SMILES O=C(Nc1nc(cn2cc(nc12)-c1ccccc1)-c1ccccc1)c1cccnc1 Show InChI InChI=1S/C24H17N5O/c30-24(19-12-7-13-25-14-19)28-22-23-27-21(18-10-5-2-6-11-18)16-29(23)15-20(26-22)17-8-3-1-4-9-17/h1-16H,(H,26,28,30) | UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 172 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description
Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes after 120 mins by scintillation counting method |
Eur J Med Chem 125: 611-628 (2017)
BindingDB Entry DOI: 10.7270/Q2VM4FPF |
More data for this
Ligand-Target Pair | |
Cyclin-Dependent Kinase 9 (CDK9)
(Homo sapiens (Human)) | BDBM50259411
(CHEMBL4086402)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C17H17F3N4O/c1-2-13(10-25)22-15-6-7-16-21-9-14(24(16)23-15)11-4-3-5-12(8-11)17(18,19)20/h3-9,13,25H,2,10H2,1H3,(H,22,23)/t13-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK2/cyclin A after 30 mins by [gamma-33P]ATP based scintillation counting analysis |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Cyclin-Dependent Kinase 9 (CDK9)
(Homo sapiens (Human)) | BDBM50259410
(CHEMBL4100956)Show InChI InChI=1S/C15H17N5O/c1-2-12(10-21)18-14-5-6-15-17-9-13(20(15)19-14)11-4-3-7-16-8-11/h3-9,12,21H,2,10H2,1H3,(H,18,19)/t12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by [gamma-33P]ATP based scintillation counting analysis |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Cyclin-Dependent Kinase 5 (CDK5)
(Homo sapiens (Human)) | BDBM50259411
(CHEMBL4086402)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C17H17F3N4O/c1-2-13(10-25)22-15-6-7-16-21-9-14(24(16)23-15)11-4-3-5-12(8-11)17(18,19)20/h3-9,13,25H,2,10H2,1H3,(H,22,23)/t13-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK9/cyclin T expressed in insect cells using CDK7/9-tide as substrate after 30 mins by [gamma-33P]ATP based scintill... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Cyclin-Dependent Kinase 2 (CDK2)
(Homo sapiens (Human)) | BDBM50259410
(CHEMBL4100956)Show InChI InChI=1S/C15H17N5O/c1-2-12(10-21)18-14-5-6-15-17-9-13(20(15)19-14)11-4-3-7-16-8-11/h3-9,12,21H,2,10H2,1H3,(H,18,19)/t12-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by [gamma-33P]ATP based scintillation counting analysis |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Cyclin-Dependent Kinase 2 (CDK2)
(Homo sapiens (Human)) | BDBM50259412
(CHEMBL4080844)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(\C=C\c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C19H19F3N4O/c1-2-15(12-27)24-17-8-9-18-23-11-16(26(18)25-17)7-6-13-4-3-5-14(10-13)19(20,21)22/h3-11,15,27H,2,12H2,1H3,(H,24,25)/b7-6+/t15-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK9/cyclin T expressed in insect cells using CDK7/9-tide as substrate after 30 mins by [gamma-33P]ATP based scintill... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Cyclin-Dependent Kinase 5 (CDK5)
(Homo sapiens (Human)) | BDBM50259412
(CHEMBL4080844)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(\C=C\c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C19H19F3N4O/c1-2-15(12-27)24-17-8-9-18-23-11-16(26(18)25-17)7-6-13-4-3-5-14(10-13)19(20,21)22/h3-11,15,27H,2,12H2,1H3,(H,24,25)/b7-6+/t15-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by [gamma-33P]ATP based scintillation counting analysis |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Cyclin-Dependent Kinase 5 (CDK5)
(Homo sapiens (Human)) | BDBM50259410
(CHEMBL4100956)Show InChI InChI=1S/C15H17N5O/c1-2-12(10-21)18-14-5-6-15-17-9-13(20(15)19-14)11-4-3-7-16-8-11/h3-9,12,21H,2,10H2,1H3,(H,18,19)/t12-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK9/cyclin T expressed in insect cells using CDK7/9-tide as substrate after 30 mins by [gamma-33P]ATP based scintill... |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Cyclin-Dependent Kinase 2 (CDK2)
(Homo sapiens (Human)) | BDBM50259411
(CHEMBL4086402)Show SMILES CC[C@@H](CO)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 Show InChI InChI=1S/C17H17F3N4O/c1-2-13(10-25)22-15-6-7-16-21-9-14(24(16)23-15)11-4-3-5-12(8-11)17(18,19)20/h3-9,13,25H,2,10H2,1H3,(H,22,23)/t13-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 8.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Paris
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by [gamma-33P]ATP based scintillation counting analysis |
Eur J Med Chem 125: 696-709 (2017)
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50178427
((1R,2S)-1,2-diphenylethane-1,2-diamine | CHEMBL206...)Show InChI InChI=1S/C14H16N2/c15-13(11-7-3-1-4-8-11)14(16)12-9-5-2-6-10-12/h1-10,13-14H,15-16H2/t13-,14+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 |
Bioorg Med Chem Lett 16: 1405-9 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.038
BindingDB Entry DOI: 10.7270/Q25M659R |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50178432
((1R,2R)-1,2-diphenylethane-1,2-diamine | (R,R)-(+)...)Show InChI InChI=1S/C14H16N2/c15-13(11-7-3-1-4-8-11)14(16)12-9-5-2-6-10-12/h1-10,13-14H,15-16H2/t13-,14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 |
Bioorg Med Chem Lett 16: 1405-9 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.038
BindingDB Entry DOI: 10.7270/Q25M659R |
More data for this
Ligand-Target Pair | |
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