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13 similar compounds to monomer 50360276

Compile data set for download or QSAR
Wt: 427.4
BDBM50185262
Wt: 441.4
BDBM50278303
Wt: 393.4
BDBM50278305
Wt: 379.4
BDBM50278816
Wt: 393.4
BDBM50278817
Wt: 427.4
BDBM50298575
Wt: 427.4
BDBM50298576
Wt: 441.4
BDBM50298580
Wt: 441.4
BDBM50298582
Wt: 441.4
BDBM50360273
Wt: 455.5
BDBM50360274
Wt: 441.4
BDBM50360275
Wt: 456.4
BDBM50360277

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50185262,50278303,50278305,50278816,50278817,50298575,50298576,50298580,50298582,50360273,50360274,50360275,50360277   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50360273
PNG
(CHEMBL1933100)
Show SMILES OC(=O)C(CCc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C26H23N3O4/c30-24(29-22(26(32)33)15-14-17-8-2-1-3-9-17)19-11-5-7-13-21(19)28-25(31)23-16-18-10-4-6-12-20(18)27-23/h1-13,16,22,27H,14-15H2,(H,28,31)(H,29,30)(H,32,33)
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3.90n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-(Thr,-Nle)-CCK-9 from human CCK1 receptor expressed in COS-7 cells after 60 mins by gamma counting


J Med Chem 54: 5769-85 (2011)


Article DOI: 10.1021/jm200438b
BindingDB Entry DOI: 10.7270/Q2BP036J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50185262
PNG
((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C25H21N3O4/c29-23(28-22(25(31)32)14-16-8-2-1-3-9-16)18-11-5-7-13-20(18)27-24(30)21-15-17-10-4-6-12-19(17)26-21/h1-13,15,22,26H,14H2,(H,27,30)(H,28,29)(H,31,32)
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59.8n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-(Thr,-Nle)-CCK-9 from human CCK1 receptor expressed in COS-7 cells after 60 mins by gamma counting


J Med Chem 54: 5769-85 (2011)


Article DOI: 10.1021/jm200438b
BindingDB Entry DOI: 10.7270/Q2BP036J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50360275
PNG
(CHEMBL1933103)
Show SMILES OC(=O)[C@H](CCc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C26H23N3O4/c30-24(29-22(26(32)33)15-14-17-8-2-1-3-9-17)19-11-5-7-13-21(19)28-25(31)23-16-18-10-4-6-12-20(18)27-23/h1-13,16,22,27H,14-15H2,(H,28,31)(H,29,30)(H,32,33)/t22-/m0/s1
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973n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-(Thr,-Nle)-CCK-9 from human CCK1 receptor expressed in COS-7 cells after 60 mins by gamma counting


J Med Chem 54: 5769-85 (2011)


Article DOI: 10.1021/jm200438b
BindingDB Entry DOI: 10.7270/Q2BP036J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50360275
PNG
(CHEMBL1933103)
Show SMILES OC(=O)[C@H](CCc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C26H23N3O4/c30-24(29-22(26(32)33)15-14-17-8-2-1-3-9-17)19-11-5-7-13-21(19)28-25(31)23-16-18-10-4-6-12-20(18)27-23/h1-13,16,22,27H,14-15H2,(H,28,31)(H,29,30)(H,32,33)/t22-/m0/s1
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1.00E+3n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-(Thr,-Nle)-CCK-9 from human CCK2 receptor expressed in COS-7 cells after 60 mins by gamma counting


J Med Chem 54: 5769-85 (2011)


Article DOI: 10.1021/jm200438b
BindingDB Entry DOI: 10.7270/Q2BP036J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50185262
PNG
((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C25H21N3O4/c29-23(28-22(25(31)32)14-16-8-2-1-3-9-16)18-11-5-7-13-20(18)27-24(30)21-15-17-10-4-6-12-19(17)26-21/h1-13,15,22,26H,14H2,(H,27,30)(H,28,29)(H,31,32)
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>1.00E+4n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [125I]CCK-8S from human CCK2R


J Med Chem 49: 6371-90 (2006)


Article DOI: 10.1021/jm060590x
BindingDB Entry DOI: 10.7270/Q2MK6CHM
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50360273
PNG
(CHEMBL1933100)
Show SMILES OC(=O)C(CCc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C26H23N3O4/c30-24(29-22(26(32)33)15-14-17-8-2-1-3-9-17)19-11-5-7-13-21(19)28-25(31)23-16-18-10-4-6-12-20(18)27-23/h1-13,16,22,27H,14-15H2,(H,28,31)(H,29,30)(H,32,33)
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1.53E+4n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-(Thr,-Nle)-CCK-9 from human CCK2 receptor expressed in COS-7 cells after 60 mins by gamma counting


J Med Chem 54: 5769-85 (2011)


Article DOI: 10.1021/jm200438b
BindingDB Entry DOI: 10.7270/Q2BP036J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50185262
PNG
((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C25H21N3O4/c29-23(28-22(25(31)32)14-16-8-2-1-3-9-16)18-11-5-7-13-20(18)27-24(30)21-15-17-10-4-6-12-19(17)26-21/h1-13,15,22,26H,14H2,(H,27,30)(H,28,29)(H,31,32)
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2.20E+4n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-(Thr,-Nle)-CCK-9 from human CCK2 receptor expressed in COS-7 cells after 60 mins by gamma counting


J Med Chem 54: 5769-85 (2011)


Article DOI: 10.1021/jm200438b
BindingDB Entry DOI: 10.7270/Q2BP036J
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50185262
PNG
((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C25H21N3O4/c29-23(28-22(25(31)32)14-16-8-2-1-3-9-16)18-11-5-7-13-20(18)27-24(30)21-15-17-10-4-6-12-19(17)26-21/h1-13,15,22,26H,14H2,(H,27,30)(H,28,29)(H,31,32)
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n/an/a 1.64E+4n/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-CCK8 from CCK1 receptor in Hartley guinea pig cerebral cortex


Bioorg Med Chem 17: 2336-50 (2009)


Article DOI: 10.1016/j.bmc.2009.02.012
BindingDB Entry DOI: 10.7270/Q27S7NNR
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50278303
PNG
(3-(R,S)-{2-[(1H-Indole-2-carbonyl)-amino]-benzoyla...)
Show SMILES OC(=O)CC(Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C26H23N3O4/c30-24(31)16-19(14-17-8-2-1-3-9-17)27-25(32)20-11-5-7-13-22(20)29-26(33)23-15-18-10-4-6-12-21(18)28-23/h1-13,15,19,28H,14,16H2,(H,27,32)(H,29,33)(H,30,31)
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n/an/a 1.69E+4n/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-CCK8 from CCK1 receptor in Hartley guinea pig cerebral cortex


Bioorg Med Chem 17: 2336-50 (2009)


Article DOI: 10.1016/j.bmc.2009.02.012
BindingDB Entry DOI: 10.7270/Q27S7NNR
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50278816
PNG
(2-(R,S)-{2-[(1H-Indole-2-carbonyl)-amino]-benzoyla...)
Show SMILES CC(C)C(NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1)C(O)=O
Show InChI InChI=1S/C21H21N3O4/c1-12(2)18(21(27)28)24-19(25)14-8-4-6-10-16(14)23-20(26)17-11-13-7-3-5-9-15(13)22-17/h3-12,18,22H,1-2H3,(H,23,26)(H,24,25)(H,27,28)
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n/an/a 2.74E+4n/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-CCK8 from CCK1 receptor in Hartley guinea pig cerebral cortex


Bioorg Med Chem 17: 2336-50 (2009)


Article DOI: 10.1016/j.bmc.2009.02.012
BindingDB Entry DOI: 10.7270/Q27S7NNR
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50185262
PNG
((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C25H21N3O4/c29-23(28-22(25(31)32)14-16-8-2-1-3-9-16)18-11-5-7-13-20(18)27-24(30)21-15-17-10-4-6-12-19(17)26-21/h1-13,15,22,26H,14H2,(H,27,30)(H,28,29)(H,31,32)
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n/an/a 197n/an/an/an/an/an/a



Aristotelian University of Thessaloniki

Curated by ChEMBL


Assay Description
Displacement of [125I]-CCK8 from CCK1 receptor in rat pancreatic acinar cells


Bioorg Med Chem 17: 5198-206 (2009)


Article DOI: 10.1016/j.bmc.2009.05.067
BindingDB Entry DOI: 10.7270/Q2QC03JB
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50298575
PNG
((S)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-phe...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C25H21N3O4/c29-23(28-22(25(31)32)14-16-8-2-1-3-9-16)18-11-5-7-13-20(18)27-24(30)21-15-17-10-4-6-12-19(17)26-21/h1-13,15,22,26H,14H2,(H,27,30)(H,28,29)(H,31,32)/t22-/m0/s1
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n/an/a 1.02E+4n/an/an/an/an/an/a



Aristotelian University of Thessaloniki

Curated by ChEMBL


Assay Description
Displacement of [125I]-CCK8 from CCK1 receptor in rat pancreatic acinar cells


Bioorg Med Chem 17: 5198-206 (2009)


Article DOI: 10.1016/j.bmc.2009.05.067
BindingDB Entry DOI: 10.7270/Q2QC03JB
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50298576
PNG
((R)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-phe...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C25H21N3O4/c29-23(28-22(25(31)32)14-16-8-2-1-3-9-16)18-11-5-7-13-20(18)27-24(30)21-15-17-10-4-6-12-19(17)26-21/h1-13,15,22,26H,14H2,(H,27,30)(H,28,29)(H,31,32)/t22-/m1/s1
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n/an/a 106n/an/an/an/an/an/a



Aristotelian University of Thessaloniki

Curated by ChEMBL


Assay Description
Displacement of [125I]-CCK8 from CCK1 receptor in rat pancreatic acinar cells


Bioorg Med Chem 17: 5198-206 (2009)


Article DOI: 10.1016/j.bmc.2009.05.067
BindingDB Entry DOI: 10.7270/Q2QC03JB
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50298580
PNG
((+/-)-2-(2-(5-methyl-1H-indole-2-carboxamido)benza...)
Show SMILES Cc1ccc2[nH]c(cc2c1)C(=O)Nc1ccccc1C(=O)NC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C26H23N3O4/c1-16-11-12-20-18(13-16)15-22(27-20)25(31)28-21-10-6-5-9-19(21)24(30)29-23(26(32)33)14-17-7-3-2-4-8-17/h2-13,15,23,27H,14H2,1H3,(H,28,31)(H,29,30)(H,32,33)
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n/an/a 2.79E+3n/an/an/an/an/an/a



Aristotelian University of Thessaloniki

Curated by ChEMBL


Assay Description
Displacement of [125I]-CCK8 from CCK1 receptor in rat pancreatic acinar cells


Bioorg Med Chem 17: 5198-206 (2009)


Article DOI: 10.1016/j.bmc.2009.05.067
BindingDB Entry DOI: 10.7270/Q2QC03JB
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50298582
PNG
((+/-)-2-(2-(7-methyl-1H-indole-2-carboxamido)benza...)
Show SMILES Cc1cccc2cc([nH]c12)C(=O)Nc1ccccc1C(=O)NC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C26H23N3O4/c1-16-8-7-11-18-15-21(27-23(16)18)25(31)28-20-13-6-5-12-19(20)24(30)29-22(26(32)33)14-17-9-3-2-4-10-17/h2-13,15,22,27H,14H2,1H3,(H,28,31)(H,29,30)(H,32,33)
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n/an/a 671n/an/an/an/an/an/a



Aristotelian University of Thessaloniki

Curated by ChEMBL


Assay Description
Displacement of [125I]-CCK8 from CCK1 receptor in rat pancreatic acinar cells


Bioorg Med Chem 17: 5198-206 (2009)


Article DOI: 10.1016/j.bmc.2009.05.067
BindingDB Entry DOI: 10.7270/Q2QC03JB
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50360273
PNG
(CHEMBL1933100)
Show SMILES OC(=O)C(CCc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C26H23N3O4/c30-24(29-22(26(32)33)15-14-17-8-2-1-3-9-17)19-11-5-7-13-21(19)28-25(31)23-16-18-10-4-6-12-20(18)27-23/h1-13,16,22,27H,14-15H2,(H,28,31)(H,29,30)(H,32,33)
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n/an/a 15.7n/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]-BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acini after 120 hrs by gamma-counting


J Med Chem 54: 5769-85 (2011)


Article DOI: 10.1021/jm200438b
BindingDB Entry DOI: 10.7270/Q2BP036J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50360274
PNG
(CHEMBL1933101)
Show SMILES OC(=O)C(CCCc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C27H25N3O4/c31-25(30-23(27(33)34)16-8-11-18-9-2-1-3-10-18)20-13-5-7-15-22(20)29-26(32)24-17-19-12-4-6-14-21(19)28-24/h1-7,9-10,12-15,17,23,28H,8,11,16H2,(H,29,32)(H,30,31)(H,33,34)
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n/an/a 107n/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]-BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acini after 120 hrs by gamma-counting


J Med Chem 54: 5769-85 (2011)


Article DOI: 10.1021/jm200438b
BindingDB Entry DOI: 10.7270/Q2BP036J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50360275
PNG
(CHEMBL1933103)
Show SMILES OC(=O)[C@H](CCc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C26H23N3O4/c30-24(29-22(26(32)33)15-14-17-8-2-1-3-9-17)19-11-5-7-13-21(19)28-25(31)23-16-18-10-4-6-12-20(18)27-23/h1-13,16,22,27H,14-15H2,(H,28,31)(H,29,30)(H,32,33)/t22-/m0/s1
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n/an/a 313n/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]-BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acini after 120 hrs by gamma-counting


J Med Chem 54: 5769-85 (2011)


Article DOI: 10.1021/jm200438b
BindingDB Entry DOI: 10.7270/Q2BP036J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50360277
PNG
(CHEMBL1933108)
Show SMILES ONC(=O)C(CCc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C26H24N4O4/c31-24(29-22(26(33)30-34)15-14-17-8-2-1-3-9-17)19-11-5-7-13-21(19)28-25(32)23-16-18-10-4-6-12-20(18)27-23/h1-13,16,22,27,34H,14-15H2,(H,28,32)(H,29,31)(H,30,33)
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n/an/a 419n/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]-BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acini after 120 hrs by gamma-counting


J Med Chem 54: 5769-85 (2011)


Article DOI: 10.1021/jm200438b
BindingDB Entry DOI: 10.7270/Q2BP036J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50185262
PNG
((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C25H21N3O4/c29-23(28-22(25(31)32)14-16-8-2-1-3-9-16)18-11-5-7-13-20(18)27-24(30)21-15-17-10-4-6-12-19(17)26-21/h1-13,15,22,26H,14H2,(H,27,30)(H,28,29)(H,31,32)
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n/an/a 197n/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]-BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acini after 120 hrs by gamma-counting


J Med Chem 54: 5769-85 (2011)


Article DOI: 10.1021/jm200438b
BindingDB Entry DOI: 10.7270/Q2BP036J
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50278817
PNG
(2-(R,S)-{2-[(1H-Indole-2-carbonyl)-amino]-benzoyla...)
Show SMILES CC(C)CC(NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1)C(O)=O
Show InChI InChI=1S/C22H23N3O4/c1-13(2)11-19(22(28)29)25-20(26)15-8-4-6-10-17(15)24-21(27)18-12-14-7-3-5-9-16(14)23-18/h3-10,12-13,19,23H,11H2,1-2H3,(H,24,27)(H,25,26)(H,28,29)
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n/an/a 83n/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cells


Bioorg Med Chem 17: 2336-50 (2009)


Article DOI: 10.1016/j.bmc.2009.02.012
BindingDB Entry DOI: 10.7270/Q27S7NNR
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50278305
PNG
(2(R)-{2-[(1H-Indole-2-carbonyl)-amino]-benzoylamin...)
Show SMILES CC(C)C[C@@H](NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1)C(O)=O
Show InChI InChI=1S/C22H23N3O4/c1-13(2)11-19(22(28)29)25-20(26)15-8-4-6-10-17(15)24-21(27)18-12-14-7-3-5-9-16(14)23-18/h3-10,12-13,19,23H,11H2,1-2H3,(H,24,27)(H,25,26)(H,28,29)/t19-/m1/s1
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n/an/a 46n/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cells


Bioorg Med Chem 17: 2336-50 (2009)


Article DOI: 10.1016/j.bmc.2009.02.012
BindingDB Entry DOI: 10.7270/Q27S7NNR
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50185262
PNG
((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C25H21N3O4/c29-23(28-22(25(31)32)14-16-8-2-1-3-9-16)18-11-5-7-13-20(18)27-24(30)21-15-17-10-4-6-12-19(17)26-21/h1-13,15,22,26H,14H2,(H,27,30)(H,28,29)(H,31,32)
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n/an/a 197n/an/an/an/an/an/a



University of Naples Federico II

Curated by ChEMBL


Assay Description
Displacement of [111In]-DTPAGlu-Gly-[Tyr27(SO3)]-CCK8 from human CCK1 receptor in A431 cells


J Med Chem 49: 2456-62 (2006)


Article DOI: 10.1021/jm051050n
BindingDB Entry DOI: 10.7270/Q2Q81CPS
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50185262
PNG
((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C25H21N3O4/c29-23(28-22(25(31)32)14-16-8-2-1-3-9-16)18-11-5-7-13-20(18)27-24(30)21-15-17-10-4-6-12-19(17)26-21/h1-13,15,22,26H,14H2,(H,27,30)(H,28,29)(H,31,32)
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n/an/a 197n/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cells


Bioorg Med Chem 17: 2336-50 (2009)


Article DOI: 10.1016/j.bmc.2009.02.012
BindingDB Entry DOI: 10.7270/Q27S7NNR
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50278816
PNG
(2-(R,S)-{2-[(1H-Indole-2-carbonyl)-amino]-benzoyla...)
Show SMILES CC(C)C(NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1)C(O)=O
Show InChI InChI=1S/C21H21N3O4/c1-12(2)18(21(27)28)24-19(25)14-8-4-6-10-16(14)23-20(26)17-11-13-7-3-5-9-15(13)22-17/h3-12,18,22H,1-2H3,(H,23,26)(H,24,25)(H,27,28)
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n/an/a 288n/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cells


Bioorg Med Chem 17: 2336-50 (2009)


Article DOI: 10.1016/j.bmc.2009.02.012
BindingDB Entry DOI: 10.7270/Q27S7NNR
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)
BDBM50278305
PNG
(2(R)-{2-[(1H-Indole-2-carbonyl)-amino]-benzoylamin...)
Show SMILES CC(C)C[C@@H](NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1)C(O)=O
Show InChI InChI=1S/C22H23N3O4/c1-13(2)11-19(22(28)29)25-20(26)15-8-4-6-10-17(15)24-21(27)18-12-14-7-3-5-9-16(14)23-18/h3-10,12-13,19,23H,11H2,1-2H3,(H,24,27)(H,25,26)(H,28,29)/t19-/m1/s1
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n/an/a 1.47E+4n/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [125I]BH-CCK8 from CCK1 receptor in Hartley guinea pig cerebral cortex


Bioorg Med Chem 17: 2336-50 (2009)


Article DOI: 10.1016/j.bmc.2009.02.012
BindingDB Entry DOI: 10.7270/Q27S7NNR
More data for this
Ligand-Target Pair