Found 4 hits for monomerid = 50185583,50185591,50185597,50185602 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)
(Homo sapiens (Human)) | BDBM50185583
((E)-2-(N-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)Show SMILES COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CN(CCP(O)(O)=O)C(C)=O Show InChI InChI=1S/C19H26NO8P/c1-11(9-20(13(3)21)7-8-29(24,25)26)5-6-14-17(22)16-15(10-28-19(16)23)12(2)18(14)27-4/h5,22H,6-10H2,1-4H3,(H2,24,25,26)/b11-5+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 785 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences Inc
Curated by ChEMBL
| Assay Description
Inhibition of human IMPDH2 |
Bioorg Med Chem Lett 16: 3479-83 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.097
BindingDB Entry DOI: 10.7270/Q2HH6JP9 |
More data for this
Ligand-Target Pair | |
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)
(Homo sapiens (Human)) | BDBM50185602
((E)-2-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-d...)Show SMILES COc1c(C)c2COC(=O)c2c(O)c1CC=C(C)CNCCP(O)(O)=O Show InChI InChI=1S/C17H24NO7P/c1-10(8-18-6-7-26(21,22)23)4-5-12-15(19)14-13(9-25-17(14)20)11(2)16(12)24-3/h4,18-19H,5-9H2,1-3H3,(H2,21,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 499 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences Inc
Curated by ChEMBL
| Assay Description
Inhibition of human IMPDH2 |
Bioorg Med Chem Lett 16: 3479-83 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.097
BindingDB Entry DOI: 10.7270/Q2HH6JP9 |
More data for this
Ligand-Target Pair | |
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)
(Homo sapiens (Human)) | BDBM50185597
((E)-2-(N-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)Show SMILES COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CN(CCP(O)(O)=O)C=O Show InChI InChI=1S/C18H24NO8P/c1-11(8-19(10-20)6-7-28(23,24)25)4-5-13-16(21)15-14(9-27-18(15)22)12(2)17(13)26-3/h4,10,21H,5-9H2,1-3H3,(H2,23,24,25)/b11-4+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 749 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences Inc
Curated by ChEMBL
| Assay Description
Inhibition of human IMPDH2 |
Bioorg Med Chem Lett 16: 3479-83 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.097
BindingDB Entry DOI: 10.7270/Q2HH6JP9 |
More data for this
Ligand-Target Pair | |
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)
(Homo sapiens (Human)) | BDBM50185591
((E)-2-((4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-...)Show SMILES COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CN(C)CCP(O)(O)=O Show InChI InChI=1S/C18H26NO7P/c1-11(9-19(3)7-8-27(22,23)24)5-6-13-16(20)15-14(10-26-18(15)21)12(2)17(13)25-4/h5,20H,6-10H2,1-4H3,(H2,22,23,24)/b11-5+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences Inc
Curated by ChEMBL
| Assay Description
Inhibition of human IMPDH2 |
Bioorg Med Chem Lett 16: 3479-83 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.097
BindingDB Entry DOI: 10.7270/Q2HH6JP9 |
More data for this
Ligand-Target Pair | |
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