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3 similar compounds to monomer 50194534

Compile data set for download or QSAR
Wt: 381.5
BDBM50194537
Wt: 471.6
BDBM50194543
Wt: 485.6
BDBM50194545

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194537,50194543,50194545   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv1.5


(Homo sapiens (Human))
BDBM50194537
PNG
(CHEMBL217473 | N1,N1-diisopropyl-N5-methyl-3-pheny...)
Show SMILES CNC(=O)CC(C(C(=O)N(C(C)C)C(C)C)c1cccnc1)c1ccccc1
Show InChI InChI=1S/C23H31N3O2/c1-16(2)26(17(3)4)23(28)22(19-12-9-13-25-15-19)20(14-21(27)24-5)18-10-7-6-8-11-18/h6-13,15-17,20,22H,14H2,1-5H3,(H,24,27)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.67E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5


Bioorg Med Chem Lett 16: 5897-901 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.054
BindingDB Entry DOI: 10.7270/Q2Z60NP6
More data for this
Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5


(Homo sapiens (Human))
BDBM50194545
PNG
(CHEMBL439539 | N1,N1-diisopropyl-3-phenyl-N5-(3-ph...)
Show SMILES CC(C)N(C(C)C)C(=O)C(C(CC(=O)NCCCc1ccccc1)c1ccccc1)c1cccnc1
Show InChI InChI=1S/C31H39N3O2/c1-23(2)34(24(3)4)31(36)30(27-18-12-19-32-22-27)28(26-16-9-6-10-17-26)21-29(35)33-20-11-15-25-13-7-5-8-14-25/h5-10,12-14,16-19,22-24,28,30H,11,15,20-21H2,1-4H3,(H,33,35)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 589n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5


Bioorg Med Chem Lett 16: 5897-901 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.054
BindingDB Entry DOI: 10.7270/Q2Z60NP6
More data for this
Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5


(Homo sapiens (Human))
BDBM50194543
PNG
(CHEMBL384706 | N1,N1-diisopropyl-N5-phenethyl-3-ph...)
Show SMILES CC(C)N(C(C)C)C(=O)C(C(CC(=O)NCCc1ccccc1)c1ccccc1)c1cccnc1
Show InChI InChI=1S/C30H37N3O2/c1-22(2)33(23(3)4)30(35)29(26-16-11-18-31-21-26)27(25-14-9-6-10-15-25)20-28(34)32-19-17-24-12-7-5-8-13-24/h5-16,18,21-23,27,29H,17,19-20H2,1-4H3,(H,32,34)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 410n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5


Bioorg Med Chem Lett 16: 5897-901 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.054
BindingDB Entry DOI: 10.7270/Q2Z60NP6
More data for this
Ligand-Target Pair