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1 similar compounds to monomer 50197297

Compile data set for download or QSAR
Wt: 392.4
BDBM50197280

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50197280   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-serine O-palmitoleoyltransferase porcupine


(Mus musculus)
BDBM50197280
PNG
(CHEMBL3968159)
Show SMILES Cc1cc(ccn1)-c1ccc(CNC(=O)c2ccc3c(c2)oc2ccccc32)cc1
Show InChI InChI=1S/C26H20N2O2/c1-17-14-20(12-13-27-17)19-8-6-18(7-9-19)16-28-26(29)21-10-11-23-22-4-2-3-5-24(22)30-25(23)15-21/h2-15H,16H2,1H3,(H,28,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.10n/an/an/an/an/an/a



Soochow University

Curated by ChEMBL


Assay Description
Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells after 48 hrs by Super-top flash reporter gene assay


Bioorg Med Chem 24: 5861-5872 (2016)


Article DOI: 10.1016/j.bmc.2016.09.041
BindingDB Entry DOI: 10.7270/Q2HQ41VN
More data for this
Ligand-Target Pair