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2 similar compounds to monomer 50004779

Compile data set for download or QSAR
Wt: 426.5
BDBM50226617
Wt: 548.7
BDBM50226618

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226617,50226618   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 3


(Homo sapiens (Human))
BDBM50226618
PNG
(CHEMBL106201)
Show SMILES O=C(CCCOc1ccc2N=C3NC(=O)CN3Cc2c1)C(CC1CCCCN1)(C1CCCCC1)C1CCCCC1
Show InChI InChI=1S/C33H48N4O3/c38-30(15-9-19-40-28-16-17-29-24(20-28)22-37-23-31(39)36-32(37)35-29)33(25-10-3-1-4-11-25,26-12-5-2-6-13-26)21-27-14-7-8-18-34-27/h16-17,20,25-27,34H,1-15,18-19,21-23H2,(H,35,36,39)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.90n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vivo inhibition of cyclic AMP phosphodiesterase from human platelets


J Med Chem 30: 303-18 (1987)


Article DOI: 10.1021/jm00385a012
More data for this
Ligand-Target Pair
Phosphodiesterase 3


(Homo sapiens (Human))
BDBM50226617
PNG
(CHEMBL110567)
Show SMILES CC(C)[C@@H]1N2Cc3cc(OCCCC(=O)N(C)C4CCCCC4)ccc3N=C2NC1=O
Show InChI InChI=1S/C24H34N4O3/c1-16(2)22-23(30)26-24-25-20-12-11-19(14-17(20)15-28(22)24)31-13-7-10-21(29)27(3)18-8-5-4-6-9-18/h11-12,14,16,18,22H,4-10,13,15H2,1-3H3,(H,25,26,30)/t22-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vivo inhibition of cyclic AMP phosphodiesterase from human platelets


J Med Chem 30: 303-18 (1987)


Article DOI: 10.1021/jm00385a012
More data for this
Ligand-Target Pair