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14 similar compounds to monomer 50229504

Compile data set for download or QSAR
Wt: 303.3
BDBM50229499
Wt: 349.2
BDBM50229500
Wt: 412.9
BDBM50229478
Wt: 411.8
BDBM50229479
Wt: 499.0
BDBM50229482
Wt: 420.8
BDBM50229484
Wt: 672.2
BDBM50229486
Wt: 439.9
BDBM50229487
Wt: 567.0
BDBM50229480
Wt: 479.9
BDBM50229483
Wt: 413.8
BDBM50229485
Wt: 409.4
BDBM50229473
Wt: 443.3
BDBM50229474
Wt: 364.4
BDBM50229475

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50229499,50229500,50229478,50229479,50229482,50229484,50229486,50229487,50229480,50229483,50229485,50229473,50229474,50229475   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(RAT)
BDBM50229473
PNG
(CHEMBL315724)
Show SMILES CCCCc1nc(c(CO)n1Cc1ccc(cc1)-c1ccccc1C(O)=O)[N+]([O-])=O
Show InChI InChI=1S/C22H23N3O5/c1-2-3-8-20-23-21(25(29)30)19(14-26)24(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22(27)28/h4-7,9-12,26H,2-3,8,13-14H2,1H3,(H,27,28)
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n/an/a 260n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50229474
PNG
(CHEMBL87315)
Show SMILES CCCCc1nc(Br)c(CO)n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C22H23BrN2O3/c1-2-3-8-20-24-21(23)19(14-26)25(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22(27)28/h4-7,9-12,26H,2-3,8,13-14H2,1H3,(H,27,28)
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n/an/a 90n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50229475
PNG
(CHEMBL313927)
Show SMILES CCCc1nc(C)c(CO)n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C22H24N2O3/c1-3-6-21-23-15(2)20(14-25)24(21)13-16-9-11-17(12-10-16)18-7-4-5-8-19(18)22(26)27/h4-5,7-12,25H,3,6,13-14H2,1-2H3,(H,26,27)
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n/an/a 1.80E+3n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50229478
PNG
(CHEMBL419120)
Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1cccc(C)c1C(O)=O
Show InChI InChI=1S/C23H25ClN2O3/c1-3-4-8-20-25-22(24)19(14-27)26(20)13-16-9-11-17(12-10-16)18-7-5-6-15(2)21(18)23(28)29/h5-7,9-12,27H,3-4,8,13-14H2,1-2H3,(H,28,29)
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n/an/a 1.90E+3n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50229479
PNG
(CHEMBL88017)
Show SMILES CCCCc1nc(Cl)c(C(N)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C22H22ClN3O3/c1-2-3-8-18-25-20(23)19(21(24)27)26(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)22(28)29/h4-7,9-12H,2-3,8,13H2,1H3,(H2,24,27)(H,28,29)
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n/an/a 150n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50229480
PNG
(CHEMBL87774)
Show SMILES CCCCc1nc(Cl)c(CNC(=O)Nc2cccc3ccccc23)n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C33H31ClN4O3/c1-2-3-15-30-37-31(34)29(20-35-33(41)36-28-14-8-10-23-9-4-5-12-26(23)28)38(30)21-22-16-18-24(19-17-22)25-11-6-7-13-27(25)32(39)40/h4-14,16-19H,2-3,15,20-21H2,1H3,(H,39,40)(H2,35,36,41)
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n/an/a 3.00E+3n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50229500
PNG
(CHEMBL86736)
Show SMILES COc1cc(\C=C/c2ccc(Br)cc2)cc(OC)c1OC
Show InChI InChI=1S/C17H17BrO3/c1-19-15-10-13(11-16(20-2)17(15)21-3)5-4-12-6-8-14(18)9-7-12/h4-11H,1-3H3/b5-4-
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n/an/a 3.10E+3n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to inhibit Tubulin polymerization in Bovine brain


J Med Chem 34: 2579-88 (1991)


Article DOI: 10.1021/jm00112a036
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50229483
PNG
(CHEMBL313130)
Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1[nH]nnc1C(=O)OC
Show InChI InChI=1S/C25H26ClN5O3/c1-3-4-9-21-27-24(26)20(15-32)31(21)14-16-10-12-17(13-11-16)18-7-5-6-8-19(18)22-23(25(33)34-2)29-30-28-22/h5-8,10-13,32H,3-4,9,14-15H2,1-2H3,(H,28,29,30)
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n/an/a 260n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50229484
PNG
(CHEMBL84585)
Show SMILES CCCCc1nc(Cl)c(C=O)n1Cc1ccc(cc1)-c1cccc(c1)-c1nn[nH]n1
Show InChI InChI=1S/C22H21ClN6O/c1-2-3-7-20-24-21(23)19(14-30)29(20)13-15-8-10-16(11-9-15)17-5-4-6-18(12-17)22-25-27-28-26-22/h4-6,8-12,14H,2-3,7,13H2,1H3,(H,25,26,27,28)
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n/an/a>1.00E+3n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50229485
PNG
(CHEMBL313534)
Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1C(=O)NO
Show InChI InChI=1S/C22H24ClN3O3/c1-2-3-8-20-24-21(23)19(14-27)26(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22(28)25-29/h4-7,9-12,27,29H,2-3,8,13-14H2,1H3,(H,25,28)
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n/an/a 4.10E+3n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50229486
PNG
(CHEMBL314818)
Show SMILES CCCCc1nc(Cl)c(CNC(=O)c2cc3c(OCC(O)CNC(C)C)cccc3[nH]2)n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C37H42ClN5O5/c1-4-5-13-34-42-35(38)32(43(34)21-24-14-16-25(17-15-24)27-9-6-7-10-28(27)37(46)47)20-40-36(45)31-18-29-30(41-31)11-8-12-33(29)48-22-26(44)19-39-23(2)3/h6-12,14-18,23,26,39,41,44H,4-5,13,19-22H2,1-3H3,(H,40,45)(H,46,47)
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n/an/a 380n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50229487
PNG
(CHEMBL315247)
Show SMILES CCCCc1nc(Cl)c(C(=O)N(C)C)n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C24H26ClN3O3/c1-4-5-10-20-26-22(25)21(23(29)27(2)3)28(20)15-16-11-13-17(14-12-16)18-8-6-7-9-19(18)24(30)31/h6-9,11-14H,4-5,10,15H2,1-3H3,(H,30,31)
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n/an/a 1.30E+3n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50229499
PNG
(CHEMBL87353)
Show SMILES COc1ccc(CNc2cc(OC)c(OC)c(OC)c2)cc1
Show InChI InChI=1S/C17H21NO4/c1-19-14-7-5-12(6-8-14)11-18-13-9-15(20-2)17(22-4)16(10-13)21-3/h5-10,18H,11H2,1-4H3
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n/an/a>5.00E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to inhibit Tubulin polymerization in Bovine brain


J Med Chem 34: 2579-88 (1991)


Article DOI: 10.1021/jm00112a036
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50229482
PNG
(CHEMBL82445)
Show SMILES CCCCc1nc(Cl)c(C(O)c2ccccc2)n1Cc1ccc(cc1)-c1ccccc1-c1nn[nH]n1
Show InChI InChI=1S/C28H27ClN6O/c1-2-3-13-24-30-27(29)25(26(36)21-9-5-4-6-10-21)35(24)18-19-14-16-20(17-15-19)22-11-7-8-12-23(22)28-31-33-34-32-28/h4-12,14-17,26,36H,2-3,13,18H2,1H3,(H,31,32,33,34)
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n/an/a 410n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair