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3 similar compounds to monomer 50229502

Compile data set for download or QSAR
Wt: 501.9
BDBM50229477
Wt: 270.3
BDBM50229501
Wt: 396.8
BDBM50229476

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50229477,50229501,50229476   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(RAT)
BDBM50229476
PNG
(CHEMBL85984)
Show SMILES CC\C=C\c1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C22H21ClN2O3/c1-2-3-8-20-24-21(23)19(14-26)25(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22(27)28/h3-12,26H,2,13-14H2,1H3,(H,27,28)/b8-3+
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 80n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50229501
PNG
(CHEMBL87162)
Show SMILES COc1cc(\C=C/c2ccccc2)cc(OC)c1OC
Show InChI InChI=1S/C17H18O3/c1-18-15-11-14(12-16(19-2)17(15)20-3)10-9-13-7-5-4-6-8-13/h4-12H,1-3H3/b10-9-
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.60E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to inhibit Tubulin polymerization in Bovine brain


J Med Chem 34: 2579-88 (1991)


Article DOI: 10.1021/jm00112a036
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50229477
PNG
(CHEMBL86041)
Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1NS(=O)(=O)C(F)(F)F
Show InChI InChI=1S/C22H23ClF3N3O3S/c1-2-3-8-20-27-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)28-33(31,32)22(24,25)26/h4-7,9-12,28,30H,2-3,8,13-14H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 83n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane


J Med Chem 34: 2525-47 (1991)


Article DOI: 10.1021/jm00112a031
More data for this
Ligand-Target Pair