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2 similar compounds to monomer 50275891

Compile data set for download or QSAR
Wt: 186.2
BDBM50275895
Wt: 186.2
BDBM50275889
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50275895,50275889   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lactoperoxidase


(Homo sapiens (Human))
BDBM50275889
PNG
(CHEMBL508102 | carbimazole)
Show SMILES CCOC(=O)n1ccn(C)c1=S
Show InChI InChI=1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3
PDB
MMDB

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CHEBI
CHEMBL
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MCE
KEGG
PC cid
PC sid
UniChem

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Similars

Article
PubMed
n/an/a 1.04E+4n/an/an/an/an/an/a



Institute of Science

Curated by ChEMBL


Assay Description
Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC


J Med Chem 51: 7313-7 (2009)


Article DOI: 10.1021/jm800894m
BindingDB Entry DOI: 10.7270/Q2Z31ZGK
More data for this
Ligand-Target Pair
Bile salt export pump


(Homo sapiens (Human))
BDBM50275889
PNG
(CHEMBL508102 | carbimazole)
Show SMILES CCOC(=O)n1ccn(C)c1=S
Show InChI InChI=1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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CHEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Ability to inhibit HMG-CoA reductase (HMGR) by CoA reductase inhibition screen (COR) in rats


Drug Metab Dispos 40: 2332-41 (2012)


Article DOI: 10.1124/dmd.112.047068
BindingDB Entry DOI: 10.7270/Q2ZP488M
More data for this
Ligand-Target Pair
Lactoperoxidase


(Homo sapiens (Human))
BDBM50275895
PNG
(CHEMBL469530 | methyl 3-ethyl-2-thioxo-2,3-dihydro...)
Show SMILES CCn1ccn(C(=O)OC)c1=S
Show InChI InChI=1S/C7H10N2O2S/c1-3-8-4-5-9(6(8)12)7(10)11-2/h4-5H,3H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.96E+4n/an/an/an/an/an/a



Institute of Science

Curated by ChEMBL


Assay Description
Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC


J Med Chem 51: 7313-7 (2009)


Article DOI: 10.1021/jm800894m
BindingDB Entry DOI: 10.7270/Q2Z31ZGK
More data for this
Ligand-Target Pair