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2 similar compounds to monomer 50007395

Compile data set for download or QSAR
Wt: 326.8
BDBM50281500

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281500   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50281500
PNG
(4-{4-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1...)
Show SMILES Clc1ccc(cc1)C1=CCN(CCCCc2ccncc2)CC1
Show InChI InChI=1S/C20H23ClN2/c21-20-6-4-18(5-7-20)19-10-15-23(16-11-19)14-2-1-3-17-8-12-22-13-9-17/h4-10,12-13H,1-3,11,14-16H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
1.04n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor in guinea pig brain preparation was estimated using [3H]-3-PPP as radioligand


Bioorg Med Chem Lett 3: 277-280 (1993)


Article DOI: 10.1016/S0960-894X(01)80892-1
BindingDB Entry DOI: 10.7270/Q2HH6K0R
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50281500
PNG
(4-{4-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1...)
Show SMILES Clc1ccc(cc1)C1=CCN(CCCCc2ccncc2)CC1
Show InChI InChI=1S/C20H23ClN2/c21-20-6-4-18(5-7-20)19-10-15-23(16-11-19)14-2-1-3-17-8-12-22-13-9-17/h4-10,12-13H,1-3,11,14-16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
456n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 in rat striatum using [3H]-spiperone


Bioorg Med Chem Lett 3: 277-280 (1993)


Article DOI: 10.1016/S0960-894X(01)80892-1
BindingDB Entry DOI: 10.7270/Q2HH6K0R
More data for this
Ligand-Target Pair