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3 similar compounds to monomer 50011566

Compile data set for download or QSAR
Wt: 234.2
BDBM50281614
Wt: 250.2
BDBM50408388
Wt: 250.2
BDBM50408389

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281614,50408388,50408389   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosylhomocysteinase


(Homo sapiens (Human))
BDBM50281614
PNG
(3-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-cyclopent...)
Show SMILES Nc1ncnc2n(ccc12)C1CCC(O)C1O
Show InChI InChI=1S/C11H14N4O2/c12-10-6-3-4-15(11(6)14-5-13-10)7-1-2-8(16)9(7)17/h3-5,7-9,16-17H,1-2H2,(H2,12,13,14)
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Article
n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against S-adenosyl-homocysteine hydrolase


Bioorg Med Chem Lett 3: 663-666 (1993)


Article DOI: 10.1016/S0960-894X(01)81249-X
BindingDB Entry DOI: 10.7270/Q2X92BS9
More data for this
Ligand-Target Pair
Adenosylhomocysteinase


(Mus musculus)
BDBM50408389
PNG
(CHEMBL2051757)
Show SMILES Nc1ncnc2n(ccc12)[C@H]1C[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C11H14N4O3/c12-10-5-1-2-15(11(5)14-4-13-10)6-3-7(16)9(18)8(6)17/h1-2,4,6-9,16-18H,3H2,(H2,12,13,14)/t6-,7+,8+,9-/m0/s1
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n/an/a>5.00E+5n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration of the compound against purified S-Adenosylhomocysteine hydrolase isolated from murine L929 cells


J Med Chem 40: 622-4 (1997)


Article DOI: 10.1021/jm9605039
BindingDB Entry DOI: 10.7270/Q2FF3RGN
More data for this
Ligand-Target Pair
Adenosylhomocysteinase


(Mus musculus)
BDBM50408388
PNG
(CHEMBL2051967)
Show SMILES Nc1ncnc2n(ccc12)[C@@H]1C[C@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C11H14N4O3/c12-10-5-1-2-15(11(5)14-4-13-10)6-3-7(16)9(18)8(6)17/h1-2,4,6-9,16-18H,3H2,(H2,12,13,14)/t6-,7+,8+,9-/m1/s1
PDB
MMDB

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Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration of the compound against purified S-Adenosylhomocysteine hydrolase isolated from murine L929 cells


J Med Chem 40: 622-4 (1997)


Article DOI: 10.1021/jm9605039
BindingDB Entry DOI: 10.7270/Q2FF3RGN
More data for this
Ligand-Target Pair